US2595159A
Expired / Lapsed
US
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Preparation of vitamin b12 concentrates from streptomyces griseus cultures
Assignee: Pharmacia and Upjohn Co
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Filing: 1949-02-25
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Granted: 1952-04-29
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Expires: 1969-02-25
Abstract
No abstract record available.
Inventors
- 👤 Curtis E Meyer
- 👤 Vries William H De
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 03:51
CPC Classifications
A; A61; A61K; A61K31/00; Y; Y10; Y10S; Y10S435/00; Y10S435/803; Y10S435/8215; Y10S435/822; Y10S435/886; Y10S435/897
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
81 words
A PROCESS FOR THE PREPARATION OF A CONCENTRATE HAVING VITAMIN B12 ACTIVITY FROM A STREPTOMYCES GRISEUS CULTURE CONTAINING STREPTOMYCIN, WHICH COMPRISES: ELUTING A MYCELIAL CAKE OBTAINED AS A BYPRODUCT IN THE SEPARATION OF STREPTOMYCIN FROM THE FERMENTATION BROTH, WHICH MYCELIAL CAKE IS SUBSTANTIALLY FREE FROM STREPTOMYCIN AND CONTAINS SUBSTANCES HAVING VITAMIN B12 ACTIVITY, WITH AN AQUEOUS SOLUTION OF AN ORGANIC SOLVENT OF THE GROUP CONSISTING OF WATER-MISCIBLE ALCOHOLS AS KETONES AT A PH WITHIN THE RANGE FROM APPROXIMATELY 6.0 TO 11.0.
Claim 2
Dependent Claim
81 words
A PROCESS FOR THE PREPARATION OF A CONCENTRATE HAVING VITAMIN B12 ACTIVITY FROM A STREPTOMYCES GRISEUS CULTURE CONTAINING STREPTOMYCIN, WHICH COMPRISES: ELUTING A MYCELIAL CAKE OBTAINED AS A BYPRODUCT IN THE SEPARATION OF STREPTOMYCIN FROM THE FERMENTATION BROTH, WHICH MYCELIAL CAKE IS SUBSTANTIALLY FREE FROM STREPTOMYCIN AND CONTAINS SUBSTANCES HAVING VITAMIN B12 ACTIVITY, WITH AN AQUEOUS SOLUTION OF AN ORGANIC SOLVENT OF THE GROUP CONSISTING OF WATER-MISCIBLE ALCOHOLS AS KETONES AT A PH WITHIN THE RANGE FROM APPROXIMATELY 6.0 TO 11.0.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1955-04-29 | 1955-10-29 | 1956-04-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1959-04-29 | 1959-10-29 | 1960-04-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1963-04-29 | 1963-10-29 | 1964-04-29 | $7700.00 | Window Closed / Lapsed |