US2586661A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process for the resolution of an amino-diol racemate
Assignee: Rhone Poulenc SA
•
Filing: 1950-12-06
•
Granted: 1952-02-19
•
Expires: 1970-12-06
Abstract
No abstract record available.
Inventors
- 👤 Jacob Robert Michel
- 👤 Liakhoff Leonide
- 👤 Robert Jacques Georges
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 20:32
CPC Classifications
C; C07; C07C; C07C233/00
Claims Analysis
Total Claims: 1
Claim 1
Independent Claim
98 words
PROCESS FOR THE PRODUCTION OF A THERAPEUTICALLY ACTIVE OPTICALLY ACTIVE ISOMER OF 1-PARANITROPHENYL - 2 - DICHLORACETYLAMINO PROPANE-1:3DIOL WHICH IS DEXTRO-ROTATTORY IN ETHANOL SOLUTION WHICH COMPRISES REACTING RACEMIC-1-PARANITROPHENYL - 2 - DICHLORACETYLAMINO PROPANE-1:3-DIOL WITH AN EQUIMOLECULAR QUANTITY OF SUCCINIC ANHYDRIDE IN A NEUTRAL NON-HYDROXYLIC SOLVENT, HEATING THE SOLUTION, ADDING AN ORGANIC BASE, CONTINUING TO HEAT THE SOLUTION, BASIFYING AND NEUTRALISING THE SOLUTION, TREATING THE SOLUTION WITH STRYCHNINE, CRYSTALLISING THE RESULTING MIXTURE FROM AN ORGANIC SOLVENT, FRACTIONALLY SEPARATING THE MORE SOLUBLE OPTICAL ISOMER CONTAINED IN THE MIXTURE AND SUBJECTING SAID MORE SOLUBLE ISOMER TO BASIFICATION, NEUTRALISATION AND MILD HYDROLYSIS.
References Cited (Backward Citations)
US2483885A
Cited
US2514376A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1955-02-18 | 1955-08-20 | 1956-02-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1959-02-18 | 1959-08-20 | 1960-02-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1963-02-18 | 1963-08-20 | 1964-02-19 | $7700.00 | Window Closed / Lapsed |