Patent US2326383A successfully refreshed from Google Patents.
US2584093A
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Method of purifying diphtheria toxoids
Assignee: Sharp and Dohme Inc
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Filing: 1949-07-07
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Granted: 1952-01-29
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Expires: 1969-07-07
Abstract
No abstract record available.
Inventors
- 👤 Robert B Pennell
- 👤 Masucci Peter
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 06:55
CPC Classifications
A; A61; A61K; A61K39/00; A61K39/02; A61K39/05
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
90 words
THE PROCESS OF PREPARING PURIFIED DIPTHERIA TOXOID WHICH COMPRISES ADDING TO CRUDE DIPHTHERIA TOXOID A PROTAMINE SALT TO A CONCENTRATION OF 0.05-0.30 MGM. PER CC. OF CRUDE TOXOID, ADJUSTING THE PH TO 7.0-8.3 AND THE IONIC STRENGTH TO .03-.25, ALLOWING THE MIXTURE TO STAND FOR 2,7HOURS, REMOVING AND DISCARDING THE PRECIPITATE, ADDING GLYCINE TO THE RECOVERED LIQUID TO 0.05-.5 M CONCENTRATION, ADJUSTING THE PH TO 3.0 TO 4.5, ALLOWING THE MIXTURE TO STAND FOR 4-16 HOURS UNDER REFRIGERATED TEMPERATURE, RECOVERING THE PRECIPITATE, AND DISSOLVING THE PRECIPITATE IN A SUITABLE SOLVENT.
Claim 2
Dependent Claim
90 words
THE PROCESS OF PREPARING PURIFIED DIPTHERIA TOXOID WHICH COMPRISES ADDING TO CRUDE DIPHTHERIA TOXOID A PROTAMINE SALT TO A CONCENTRATION OF 0.05-0.30 MGM. PER CC. OF CRUDE TOXOID, ADJUSTING THE PH TO 7.0-8.3 AND THE IONIC STRENGTH TO .03-.25, ALLOWING THE MIXTURE TO STAND FOR 2,7HOURS, REMOVING AND DISCARDING THE PRECIPITATE, ADDING GLYCINE TO THE RECOVERED LIQUID TO 0.05-.5 M CONCENTRATION, ADJUSTING THE PH TO 3.0 TO 4.5, ALLOWING THE MIXTURE TO STAND FOR 4-16 HOURS UNDER REFRIGERATED TEMPERATURE, RECOVERING THE PRECIPITATE, AND DISSOLVING THE PRECIPITATE IN A SUITABLE SOLVENT.
References Cited (Backward Citations)
DK56575A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1955-01-28 | 1955-07-30 | 1956-01-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1959-01-28 | 1959-07-30 | 1960-01-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1963-01-28 | 1963-07-30 | 1964-01-29 | $7700.00 | Window Closed / Lapsed |