US2506345A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method of separating live viruses from nonviral protein matter
Assignee: Wyeth Holdings LLC
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Filing: 1946-10-01
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Granted: 1950-05-02
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Expires: 1966-10-01
Abstract
No abstract record available.
Inventors
- 👤 Herald R Cox
- 👤 Aiston Stewart
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 15:09
CPC Classifications
C; C12; C12N; C12N7/00; C12N2710/00; C12N2710/00011; C12N2710/24011; C12N2710/24111; C12N2710/24151
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
137 words
AN METHOD OF SEPARATING LIVE VIRTUSES FROM NON-VIRAL PROTEIN MNATTER IN ASSOCIATION THEREWITH WITHOUT DESTRUCTION OR LOSS OF INFECTIVITY OF THE VIRUS WHICH COMPRISES THE STEPS OF SLOWLY ADDING TO A COLD AQUEOUS SUSPENSION CONTAINING LIVE VIRUS AND NON-VIRAL PROTEIN MATTER AND HAVING A PH WITHIN THE RANGE 5.0 TO 8.0 AND AN IONIC STRENGTH OF BETWEEN 0.005 AND 0.5 AT SUCH RATE AS TO AVOID DENATURATION OF SAID VIRUS FROM ABOUT 15% TO 40% BY VOLUME OF A LOWER ALIPHATIC ALCOHOL WHILE MAINTAINING THE TEMPERATURE OF THE SUSPENSION BELOW 5*C. WHEREBY DIRECT PRECIPITATION OF THE VIRUS IS CAUSED TO TAKE PLACE BY THE ACTION OF SAID ALCOHOL UNAIDED BY AND FREE FROM COPRECIPITATED ADSORBING AGENTS AND THEREAFTER SEPARATING THE PRECIPITATED INFECTIVE VIRUS FROM THE AQUEOUS PHASE WHICH RETAINS IN SOLUTION MOST OF THE NON-VIRAL PROTEIN MATTER.
Claim 2
Independent Claim
137 words
AN METHOD OF SEPARATING LIVE VIRTUSES FROM NON-VIRAL PROTEIN MNATTER IN ASSOCIATION THEREWITH WITHOUT DESTRUCTION OR LOSS OF INFECTIVITY OF THE VIRUS WHICH COMPRISES THE STEPS OF SLOWLY ADDING TO A COLD AQUEOUS SUSPENSION CONTAINING LIVE VIRUS AND NON-VIRAL PROTEIN MATTER AND HAVING A PH WITHIN THE RANGE 5.0 TO 8.0 AND AN IONIC STRENGTH OF BETWEEN 0.005 AND 0.5 AT SUCH RATE AS TO AVOID DENATURATION OF SAID VIRUS FROM ABOUT 15% TO 40% BY VOLUME OF A LOWER ALIPHATIC ALCOHOL WHILE MAINTAINING THE TEMPERATURE OF THE SUSPENSION BELOW 5*C. WHEREBY DIRECT PRECIPITATION OF THE VIRUS IS CAUSED TO TAKE PLACE BY THE ACTION OF SAID ALCOHOL UNAIDED BY AND FREE FROM COPRECIPITATED ADSORBING AGENTS AND THEREAFTER SEPARATING THE PRECIPITATED INFECTIVE VIRUS FROM THE AQUEOUS PHASE WHICH RETAINS IN SOLUTION MOST OF THE NON-VIRAL PROTEIN MATTER.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1953-05-01 | 1953-10-31 | 1954-05-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1957-05-01 | 1957-10-31 | 1958-05-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1961-05-01 | 1961-10-31 | 1962-05-02 | $7700.00 | Window Closed / Lapsed |