US20020120338A1
Expired / Lapsed
US
⏱️ 0.0 years remaining
Implants formed with demineralized bone
Assignee: Synthes USA LLC
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Filing: 2001-08-13
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Granted: —
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Expires: 2021-08-13
Abstract
Abstract Selectively partially and demineralized bone-derived implants, their methods of preparation and use are provided. In one embodiment, a cranial void filler preferably having a T-shape formed of an upper mineralized cortical bone section and at least a partially demineralized lower section adapted to fill a cranial void is disclosed. In another embodiment, a plate preferably having a dog-bone-shape having mineralized and at least partially demineralized sections is disclosed. In a further embodiment, a unitary cord having a first mineralized section with a plurality of slits to provide flexibility and a second at least partially demineralized section is described. Also disclosed is an implant for laminoplasty having at least a partially demineralized section and a mineralized section. A method of forming an implant of demineralized fibers also is disclosed.
Inventors
- 👤 Michael Boyer
- 👤 David Paul
- 👤 Christopher Angelucci
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 01:59
CPC Classifications
A; A61; A61B; A61B17/00; A61B17/04; A61B17/0401; A61B17/064; A61B17/0642; A61B17/56; A61B17/58; A61B17/68; A61B17/688; A61B17/70; A61B17/7059; A61B17/7071; A61B17/80; A61F; A61F2/00; A61F2/02; A61F2/28; A61F2/2846; A61F2/2875; A61F2/30; A61F2/44; A61F2/4455; A61F2/4465; A61L; A61L27/00; A61L27/36; A61L27/3604; A61L27/3608; A61L27/3641; A61L27/3645; A61L27/365; A61L27/3683; A61B17/7062; A61B17/8085; A61B2017/0647; A61F2/08; A61F2/2803; A61F2/3094; A61F2/442; A61F2002/2807; A61F2002/2825; A61F2002/2835; A61F2002/2839; A61F2002/30001; A61F2002/30003; A61F2002/30004; A61F2002/30011; A61F2002/30014; A61F2002/30016; A61F2002/30057; A61F2002/30059; A61F2002/3006; A61F2002/30075; A61F2002/30092; A61F2002/30108; A61F2002/3011; A61F2002/30112; A61F2002/30113; A61F2002/30125; A61F2002/30126; A61F2002/3013; A61F2002/30131; A61F2002/30138; A61F2002/30143; A61F2002/30153; A61F2002/30154; A61F2002/30159; A61F2002/30166; A61F2002/30169; A61F2002/30172; A61F2002/30199; A61F2002/30224; A61F2002/30233; A61F2002/30235; A61F2002/30261; A61F2002/30291; A61F2002/30293; A61F2002/30316; A61F2002/30317; A61F2002/30324; A61F2002/30329; A61F2002/30383; A61F2002/30387; A61F2002/30433; A61F2002/30462; A61F2002/30535; A61F2002/30576; A61F2002/30578; A61F2002/30593; A61F2002/30594; A61F2/30767; A61F2/30771; A61F2002/30772; A61F2002/30784; A61F2002/30785; A61F2002/30787; A61F2002/3082; A61F2002/30827; A61F2002/30828; A61F2002/30841; A61F2002/30843; A61F2002/30878; A61F2002/30879; A61F2002/30891; A61F2002/30892; A61F2002/30904; A61F2/30907; A61F2002/30909; A61F2002/30914; A61F2002/30971; A61F2002/30973; A61F2002/4415; A61F2002/444; A61F2/46; A61F2/4644; A61F2002/4649; A61F2210/00; A61F2210/0014; A61F2210/0061; A61F2220/00; A61F2220/0025; A61F2220/0041; A61F2220/0075; A61F2230/00; A61F2230/0002; A61F2230/0004; A61F2230/0006; A61F2230/0008; A61F2230/001; A61F2230/0013; A61F2230/0017; A61F2230/0019; A61F2230/0021; A61F2230/0028; A61F2230/0047; A61F2230/0052; A61F2230/0063; A61F2230/0069; A61F2230/0082; A61F2230/0091; A61F2250/00; A61F2250/0014; A61F2250/0018; A61F2250/0019; A61F2250/0023; A61F2250/0029; A61F2250/0036; A61F2310/00; A61F2310/00005; A61F2310/00011; A61F2310/00017; A61F2310/00023; A61L2430/00; A61L2430/02; Y; Y10; Y10S; Y10S623/00; Y10S623/915; Y10S623/919
Claims Analysis
Total Claims: 39
Claim 1
Independent Claim
38 words
1 . A cranial void filler comprising: an upper mineralized cortical bone section, and a lower, at least partially demineralized cortical bone section, wherein the lower section is adapted and configured to contact walls of a cranial void.
Claim 2
Dependent Claim
38 words
1 . A cranial void filler comprising: an upper mineralized cortical bone section, and a lower, at least partially demineralized cortical bone section, wherein the lower section is adapted and configured to contact walls of a cranial void.
Claim 3
Dependent Claim
19 words
2 . The cranial void filler of claim 1 , wherein the upper and lower sections form a T-shape.
Claim 4
Dependent Claim
32 words
3 . The cranial void filler of claim 1 , further comprising at least one slit extending through at least a portion of at least one of the upper and lower sections.
Claim 5
Dependent Claim
33 words
4 . The cranial void filler of claim 1 , wherein at least one slit extends through a portion of the upper section and at least one slit extends through the lower section.
Claim 6
Dependent Claim
29 words
5 . The cranial void filler of claim 4 , wherein the at least one slit in the lower section is colinear with the slit in the upper section.
Claim 7
Dependent Claim
20 words
6 . The cranial void filler of claim 1 , wherein the upper section has a rounded upper surface portion.
Claim 8
Dependent Claim
20 words
7 . The cranial void filler of claim 1 , wherein the upper section has a curved lower surface portion.
Claim 9
Dependent Claim
64 words
8 . A plate comprising: a unitary body with a pair of portions having a first width and a central portion disposed therebetween having a second width, the first width being greater than the second width, and the body being formed of cortical bone; and at least one partially demineralized region, wherein the at least one partially demineralized region confers flexibility to the plate.
Claim 10
Dependent Claim
64 words
8 . A plate comprising: a unitary body with a pair of portions having a first width and a central portion disposed therebetween having a second width, the first width being greater than the second width, and the body being formed of cortical bone; and at least one partially demineralized region, wherein the at least one partially demineralized region confers flexibility to the plate.
Claim 11
Dependent Claim
15 words
9 . The plate of claim 8 , further comprising a plurality of fastener holes.
Claim 12
Dependent Claim
28 words
10 . The plate of claim 9 , wherein the body has a central longitudinal axis and a first at least partially demineralized region that is coaxial therewith.
Claim 13
Dependent Claim
25 words
11 . The plate of claim 10 , wherein the first at least partially demineralized region extends substantially across the entire length of the body.
Claim 14
Dependent Claim
19 words
12 . The plate of claim 10 , wherein the fastener holes are disposed proximate ends of the body.
Claim 15
Dependent Claim
30 words
13 . The plate of claim 12 , wherein the fastener holes are disposed on a central longitudinal axis, and a first at least partially demineralized region is coaxial therewith.
Claim 16
Dependent Claim
30 words
14 . The plate of claim 13 , wherein a at least a second at least partially demineralized region is disposed transverse to the first at least partially demineralized region.
Claim 17
Dependent Claim
29 words
15 . The plate of claim 14 , wherein the at least second at least partially demineralized region is generally perpendicular to the first at least partially demineralized region.
Claim 18
Dependent Claim
24 words
16 . The plate of claim 15 , wherein the at least second at least partially demineralized region intersects at least one fastener hole.
Claim 19
Dependent Claim
20 words
17 . The plate of claim 8 , wherein the body is relatively thin compared to its length or width.
Claim 20
Dependent Claim
22 words
18 . The plate of claim 8 , wherein the at least one partially demineralized region extends substantially across the second width.
Claim 21
Dependent Claim
30 words
19 . The plate of claim 18 , wherein the body has a central longitudinal axis and the at least partially demineralized region extends transverse to the central longitudinal axis.
Claim 22
Dependent Claim
15 words
20 . The plate of claim 19 , further comprising a plurality of fastener holes.
Claim 23
Dependent Claim
15 words
21 . The plate of claim 8 , wherein the body is generally dogbone shaped.
Claim 24
Dependent Claim
35 words
22 . The plate of claim 8 , wherein the body has a central longitudinal axis, and the length of the body along the central axis is between about 10 mm and about 20 mm.
Claim 25
Dependent Claim
21 words
23 . The plate of claim 22 , wherein the first width is between about 4 mm and about 7 mm.
Claim 26
Dependent Claim
22 words
24 . The plate of claim 23 , wherein the body has a thickness between about 1 mm and about 3 mm.
Claim 27
Dependent Claim
32 words
25 . The plate of claim 23 , wherein the body has a length of about 15 mm, a first width of about 5 mm, and a thickness of about 2 mm.
Claim 28
Dependent Claim
44 words
26 . An implant comprising a unitary section of cortical bone having a first portion that is mineralized and a second portion that is at least partially demineralized, wherein the mineralized portion includes a plurality of slits to facilitate bending of the unitary section.
Claim 29
Dependent Claim
44 words
26 . An implant comprising a unitary section of cortical bone having a first portion that is mineralized and a second portion that is at least partially demineralized, wherein the mineralized portion includes a plurality of slits to facilitate bending of the unitary section.
Claim 30
Dependent Claim
34 words
27 . A method of forming an implant comprising: obtaining cortical fibers; at least partially demineralizing the fibers; allowing the fibers to clump together; and allowing the fibers to dry in a clumped state.
Claim 31
Dependent Claim
34 words
27 . A method of forming an implant comprising: obtaining cortical fibers; at least partially demineralizing the fibers; allowing the fibers to clump together; and allowing the fibers to dry in a clumped state.
Claim 32
Dependent Claim
18 words
28 . The method of claim 27 , wherein the fibers are allowed to dry in a mold.
Claim 33
Dependent Claim
19 words
29 . The method of claim 28 , further comprising pressing the fibers while the fibers are clumped together.
Claim 34
Dependent Claim
15 words
30 . The method of claim 27 , wherein the fibers are obtained by milling.
Claim 35
Dependent Claim
53 words
31 . An implant for maintaining a space in a bisected vertebrae comprising: a cortical bone cord having a first and second free ends adapted for engaging exposed portions of the lamina, and a region positioned between the first and second ends, wherein the region is at least partially demineralized to provide flexibility.
Claim 36
Dependent Claim
53 words
31 . An implant for maintaining a space in a bisected vertebrae comprising: a cortical bone cord having a first and second free ends adapted for engaging exposed portions of the lamina, and a region positioned between the first and second ends, wherein the region is at least partially demineralized to provide flexibility.
Claim 37
Dependent Claim
14 words
32 . The implant of claim 31 , wherein the free ends are mineralized.
Claim 38
Dependent Claim
27 words
33 . The implant of claim 31 , wherein the cord further comprises a pair of at least partially demineralized regions with a mineralized central region therebetween.
Claim 39
Dependent Claim
22 words
34 . The implant of claim 31 , wherein the at least partially demineralized region is centrally located between mineralized free ends.
References Cited (Backward Citations)
US6206923B1
Cited
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