Naphthoic acid derivative

Abstract

Abstract NEW MATERIAL:A naphthoic acid derivative expressed by the formula. (either one of X and Y is tertiary butyl the other is hydrogen). USE:An antifungal agent against fungi of the genus Aspergillus, Cladosporium or Chaetomium and synthetic intermediate for industrial chemicals. PREPARATION:3-Hydroxy-2-naphthoic acid and a tertiary butylating agent are subjected to Friedel-Crafts reaction to give the aimed compound expressed by the formula. Examples of the tertiary butylating agent to be used include tertiary butanol, isobutylene, etc. Examples of a catalyst to be used for the Friedel-Crafts reaction include protonic acids such as sulfuric acid, phosphoric acid, hydrochloric acid, hydrogen fluoride, etc., Lewis acid such as aluminum chloride, antimony pentachloride, ferric chloride, tin tetrachloride, titanium tetrachloride, etc.

Inventors

• 👤 Masato Maue
• 👤 真上　真諭
• 👤 Naoki Hanayama
• 👤 花山　直樹

Bibliographic Details