Alcohol-containing spreading base

Abstract

Abstract PURPOSE:The titled spreading base capable of dissolving a drug gradually and successively and continuing stable effect for a long period, comprising a specific composition capable of blending a sligthly soluble drug in an easily absorbable form. CONSTITUTION:A spreading base comprising sodium polyacrylate, carboxyvinyl polymer, water, aluminum glycinate or aluminum hydroxide gel, and ethyl alcohol as essential componets. A water-soluble alcohol-cotaining spreading base is obtained by blending 3-10 main components consisting of 3-10wt% soldium polyacrylate, 0.5-5wt% carboxyvinyl polymer, and 20-60wt% water with a material comprising carboxymethyl cellulose, and gelatin, 1-3wt% based on sodium polyacrylate of aluminum glycinate or aluminum hydroxide gel and 5-30wt% based on the total amounts of the materials of an alchol and other addition agents.

Inventors

• 👤 Fumiko Ishiguro
• 👤 文子 石黒
• 👤 Sakako Kurata
• 👤 按田　佐賀子

Bibliographic Details