Preparation of coenzyme q9

Abstract

Abstract PURPOSE: To pepare coenzyme Q 9 useful as pharmaceuticals, by culturing bacteria belonging to Pseudomonas genus in a medium containing isopentenol and/or geraniol. CONSTITUTION: Bacteria belonging to Pseudomonas genus and capable of producing coenzyme Q 9 , e.g. Pseudomonas schuylkilliensis IAM1092, IAM1126, etc. are cultured in a medium at pH 4W8 and 25W35°C for 10W50 hours with aeration and agitation. The medium is added with isopentenol and/or geraniol in one or several times so as to give the final concentration of 1×10 -5 W5×10 -3 mole/1, pref. 5× 10 -5 W5×10 -4 mole/1. The coenzyme Q 9 is separated from the cultured product by conventional solvent extraction, etc. COPYRIGHT: (C)1980,JPO&Japio

Inventors

• 👤 Hiroshi Aida
• 👤 Kinya Uchida
• 👤 Izumi Kawada

Bibliographic Details