High concentration cross-linked atelocollagen plantation composition which can be poured into body

Abstract

Abstract PURPOSE:To provide a cross-liked atelocollagen composition capable of pouring into a body which possesses low viscosity and the superior fluidity, and permits easy injection even in the use at a high concentration, and further possesses the low antigenic characteristic and is free from calcination and toxity, and possesses the superior skin prominence effect continuity. CONSTITUTION:An atelocollagen transplantable composition consists of an atelocollagen aqueous suspension which is adjusted to a physiological state by a buffer solution, and the content of atelocollagen is 55-75mg/ml, and 20-100wt.% of atelocollagen is the cross-linked atelocollagen cross-linked with a polyepoxy compound.

Inventors

• 👤 Teruo Miyata
• 👤 宮　田　暉　夫
• 👤 Tadatomo Kawai
• 👤 川　井　忠　智

Bibliographic Details