NOVEL POLYOL ESTERS, THEIR PREPARATION AND THEIR USE

Abstract

Abstract Translated from French LA PRESENTE INVENTION A POUR OBJET UN ESTER D'UN POLYOL, LEDIT POLYOL CONTENANT AU MOINS 3GROUPES HYDROXY AYANT UN POIDS MOLECULAIRE POUVANT ALLER JUSQU'A 20000, AU MOINS UN GROUPE HYDROXY DANS LEDIT POLYOL ETANT SOUS FORME D'ESTER AVEC UN RESTE D'ACIDE POLYLACTIQUE OU CO-POLYLACTIQUE AYANT CHACUN UN POIDS MOLECULAIRE D'AU MOINS 5000. CES ESTERS DE POLYOLS PEUVENT ETRE UTILISES POUR LA PREPARATION DE FORMES GALENIQUES A LIBERATION PROLONGEE. THE SUBJECT OF THE PRESENT INVENTION IS AN ESTER OF A POLYOL, LEDIT POLYOL CONTAINING AT LEAST 3 HYDROXY GROUPS HAVING A MOLECULAR WEIGHT CAPABLE OF GOING UP TO 20,000, AT LEAST ONE HYDROXY GROUP IN THESE POLYOL BEING IN THE FORM OF ESTER WITH A REMAINING ESTER. POLYLACTIC OR CO-POLYLACTIC ACID EACH HAVING A MOLECULAR WEIGHT OF AT LEAST 5000. THESE POLYOL ESTERS CAN BE USED FOR THE PREPARATION OF LONG-RELEASED GALENIC FORMS.

Inventors

• 👤 Zdenek Brich
• 👤 Thomas Kissel

Bibliographic Details