EP0875218A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Porous medicated stent
Assignee: Abbott Cardiovascular Systems Inc
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Filing: 1998-04-15
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Granted: —
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Expires: 2018-04-15
Abstract
Abstract A medicated prosthesis, such as a stent, is deployed in a human vessel. A metallic stent has a plurality of pores in the metal which are loaded with medication. When the stent is implanted into the vasculature of a patient, the medication in the stent dissipates into the tissue of the vasculature proximate the stent. The stent may be formed from a porous metal in the form of a wire, tube, or metal sheet. The present invention also includes a method of treating vasculature disease by delivering medication to the site of the vascular disease including the step of deploying a metal stent having a plurality of pores in the stent and further having medication in the pores and delivering the stent to the site of vasculature disease.
Inventors
- 👤 John Y. Yan
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-25 13:28
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/82; A61F2/92; A61L; A61L31/00; A61L31/02; A61L31/022; A61L31/08; A61L31/10; A61L31/14; A61L31/146; A61L31/16; A61F2/0077; A61F2/86; A61F2/90; A61F2/91; A61F2210/00; A61F2210/0076; A61F2250/00; A61F2250/0058; A61F2250/0067; A61F2250/0068; A61L2300/00; A61L2300/40; A61L2300/416; A61L2300/42; A61L2300/60; A61L2300/602
Claims Analysis
Total Claims: 29
Claim 1
Independent Claim
34 words
A medicated prosthesis, comprising: a metallic prosthesis configured to maintain
patency of a human vessel, the prosthesis having a
plurality of pores; and a therapeutic medication loaded into the
pores of the metallic prosthesis.
Claim 2
Dependent Claim
34 words
A medicated stent, comprising: a metallic stent configured to maintain
patency of a human vessel, the stent having a
plurality of pores; and a therapeutic medication loaded into the
pores of the metallic stent.
Claim 3
Dependent Claim
42 words
The stent of claim 2, wherein the stent is
formed of one of a group selected from a porous metal
wire, a sintered stainless steel, a sintered elemental
metal, a sintered noble metal, a sintered refractory
metal, and a sintered metal alloy.
Claim 4
Dependent Claim
27 words
The stent of claim 3, wherein the stent is
formed of one of a group selected from a shape-memory
alloy, a platinum alloy, and a gold alloy.
Claim 5
Dependent Claim
20 words
The stent of claim 2, wherein the pores are
approximately sized within the range of 0.01 microns
to 20 microns.
Claim 6
Dependent Claim
17 words
The stent of claim 2, wherein the stent is
formed of generally spherical particles that are
sintered.
Claim 7
Dependent Claim
18 words
The stent of claim 6, wherein the sintered
particles are approximately .02 microns to 20 microns
in diameter.
Claim 8
Dependent Claim
13 words
The stent of claim 2, wherein the stent is
formed of metal fibers.
Claim 9
Dependent Claim
11 words
The stent of claim 8, wherein the metallic
fibers are woven.
Claim 10
Dependent Claim
35 words
The stent of claim 2, wherein the stent has
an inner layer of particles and an outer layer of
particles, the outer layer of particles have a larger
diameter than the inner layer of particles.
Claim 11
Dependent Claim
22 words
The stent of claim 2, wherein the stent has
a non-porous core and has a porous metal coating over
the non-porous core.
Claim 12
Dependent Claim
46 words
The stent of claim 2, wherein the stent is
generally tubular and has a surface that is configured
to be embedded into the walls of the vessel, wherein
the stent is proportioned to maximize the area of the
surface while allowing efficient endothelialization of
the stent.
Claim 13
Dependent Claim
23 words
The stent of claim 2, wherein the stent is
configured to be expandable beyond the elastic limit
of the stent by a balloon.
Claim 14
Dependent Claim
13 words
The stent of claim 2, wherein the stent is
configured to be self-expanding.
Claim 15
Dependent Claim
29 words
The stent of claim 2, wherein the stent is
configured to be deployed in one of a group selected
from a blood vessel, an esophagus, and a biliary duct.
Claim 16
Dependent Claim
16 words
The stent of claim 2, further comprising a
polymeric coating over the surface of the stent.
Claim 17
Dependent Claim
25 words
The stent of claim 16, wherein the coating
is approximately in the range of 0.00254 mm to 0.051
mm (0.0001 inches to 0.002 inches) thick.
Claim 18
Dependent Claim
41 words
The stent of claim 16, wherein the coating
is of the group comprising a bio-polymer, a synthetic
polymer, a hydrogel, a heparin coating, an ionic
heparin coating that is ionic bonded, an end-point
attached heparin coating, and a photolinked heparin
coating.
Claim 19
Dependent Claim
28 words
The stent of claim 18, wherein the coating
is of the group comprising polylactic acid, fibrin,
polyurethane, polyethylene teraphthalate,
polyethylene, ethlene vinyl acetate, silicone or
polyethylene oxide (PEO).
Claim 20
Dependent Claim
25 words
The stent of claim 16, wherein the coating
is porous and the pores are sized to permit controlled
release of the medication through the pores.
Claim 21
Dependent Claim
17 words
The stent of claim 16, wherein the coating
is capable of being dissolved by the body fluids.
Claim 22
Dependent Claim
10 words
The stent of claim 16, wherein the coating
contains medication.
Claim 23
Dependent Claim
25 words
The stent of claim 16, wherein the
medication in the pores of the stent is a first
medication, wherein the coating contains a second
medication.
Claim 24
Dependent Claim
17 words
The stent of claim 16, wherein the coating
is configured to reduce the porosity of the stent.
Claim 25
Dependent Claim
18 words
The stent of claim 16, wherein the coating
is configured to improve the blood compatibility of
the stent.
Claim 26
Dependent Claim
12 words
The stent of claim 2, wherein the medication
is an antithrombogenic material.
Claim 27
Dependent Claim
19 words
The stent of claim 26, wherein the
medication is of the group comprising heparin,
ticlopodine, coumadin, dipyridamole, aspirin,
forskolin.
Claim 28
Dependent Claim
43 words
The stent of claim 26, wherein the
medication is of the group comprising an GPII b III a blocker, an anti-coagulant, an anti-fibrin agent, an
anti-thrombin agent, an anti-platelet agent, an
anti-proliferative agent, a radioactive material, a
vaso-active drug, and an anti-inflammatory agent.
Claim 29
Dependent Claim
10 words
The stent of claim 26, wherein the
medication promotes endothelialization.
References Cited (Backward Citations)
No citation records indexed.
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