EP0668075A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Non-peptide tachykinin receptor antagonists
Assignee: Eli Lilly and Co
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Filing: 1994-12-19
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Granted: —
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Expires: 2014-12-19
Abstract
Abstract This invention encompasses methods for the treatment or prevention of a physiological disorder associated with an excess of tachykinins, which method comprises administering to a mammal in need of said treatment an effective amount of a compound of Formula I wherein R 1 and R 3 are independently hydrogen, -CH 3 , wherein Ar is optionally substituted phenyl ; R 2 is selected from the group consisting of pyrrolidine, hexamthylenemino, and piperidino ; or a pharmaceutically acceptable salt of solvate thereof.
Inventors
- 👤 Bruce Donald Gitter
- 👤 William Henry Walker Lunn
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-29 18:35
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/44; A61K31/445; A61K31/4523; A61K31/4535; A61K31/40; A61K31/4025; A61P; A61P1/00; A61P11/00; A61P25/00; A61P25/04; A61P25/18; A61P25/20; A61P25/24; A61P25/26; A61P25/28; A61P29/00; A61P37/00; A61P37/08; A61P43/00; A61K31/55; C; C07; C07D; C07D409/00; C07D409/02; C07D409/10
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
67 words
The use of a compound having the formula wherein R 1 and R 3 are independently hydrogen, -CH 3 , wherein Ar is optionally substituted phenyl; R 2 is selected from the group consisting of pyrrolidino and piperidino; or a pharmaceutically acceptable salt or solvate thereof, in the preparation of a medicament useful for treatment or prevention of a physiological disorder associated with an excess of tachykinin.
Claim 2
Dependent Claim
67 words
The use of a compound having the formula wherein R 1 and R 3 are independently hydrogen, -CH 3 , wherein Ar is optionally substituted phenyl; R 2 is selected from the group consisting of pyrrolidino and piperidino; or a pharmaceutically acceptable salt or solvate thereof, in the preparation of a medicament useful for treatment or prevention of a physiological disorder associated with an excess of tachykinin.
Claim 3
Dependent Claim
13 words
The use of Claim 1 wherein said compound is the hydrochloride salt thereof.
Claim 4
Dependent Claim
10 words
The use of Claim 1 wherein said medicament is prophylactic.
Claim 5
Dependent Claim
13 words
The use of Claim 1 wherein said compound is or its hydrochloride salt.
References Cited (Backward Citations)
No citation records indexed.
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