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EP0659415A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Inhibition of vasomotor symptoms and treatment of psychological disturbances surrounding post-menopausal syndrome

Assignee: Eli Lilly and Co
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Filing: 1994-12-19
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Granted: —
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Expires: 2014-12-19
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Abstract

Abstract A method of inhibiting vasomotor symptoms and attending psychological disturbances surrounding post-menopausal syndrome comprising administering to a female human in need of treatment an effective amount of a compound having the formula wherein R 1 and R 3 are independently hydrogen, -CH 3 , wherein Ar is optionally substituted phenyl ; R 2 is selected from the group consisting of pyrrolidine, hexamethyleneamino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.

Inventors

  • 👤 George Joseph Cullinan

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-23 21:04
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/44; A61K31/445; A61K31/4523; A61K31/4535; A61K31/40; A61K31/4025; A61K31/55; A61P; A61P25/00; A61P9/00; C; C07; C07D; C07D409/00; C07D409/02; C07D409/10

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 64 words
The use of a compound having the formula wherein R 1 and R 3 are independently hydrogen, -CH 3 , wherein Ar is optionally substituted phenyl; R 2 is selected from the group consisting of pyrrolidino and piperidino; or a pharmaceutically acceptable salt or solvate thereof, in the preparation of a medicament useful for inhibiting vasomotor symptoms and attending psychological disturbances surrounding post-menopausal syndrome.
Claim 2
Dependent Claim 64 words
The use of a compound having the formula wherein R 1 and R 3 are independently hydrogen, -CH 3 , wherein Ar is optionally substituted phenyl; R 2 is selected from the group consisting of pyrrolidino and piperidino; or a pharmaceutically acceptable salt or solvate thereof, in the preparation of a medicament useful for inhibiting vasomotor symptoms and attending psychological disturbances surrounding post-menopausal syndrome.
Claim 3
Dependent Claim 13 words
The use of Claim 1 wherein said compound is the hydrochloride salt thereof.
Claim 4
Dependent Claim 10 words
The use of Claim 1 wherein said medicament is prophylactic.
Claim 5
Dependent Claim 13 words
The use of Claim 1 wherein said compound is or its hydrochloride salt.

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