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EP0659402A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Formulations containing carotenoids and procarotenoids combined with polyphenols in the prevention of the damages due to an abnormal production of free radicals

Assignee: Indena SpA
•
Filing: 1994-05-18
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Granted: —
•
Expires: 2014-05-18
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Abstract

Abstract The present invention relates to novel formulations and combinations of lipophilic and hydrophilic antioxidants and the use thereof in the therapeutic, foodstuff, dietetic, and cosmetic fields. These formulations are based on the use of carotenoids, procarotenoids and derivatives thereof with polyphenols of catechic and flavanolignane structures. Said formulations, containing a lipophilic antioxidant and an hydrophilic one at fixed ratios, can be used in the prevention of physiopatological conditions related at least partially to an over-production of free radicals, particularly aging, atherosclerosis and cancer.

Inventors

  • 👤 Ezio Bombardelli
  • 👤 Paolo Morazzoni

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-09 14:36
CPC Classifications
A; A61; A61Q; A61Q19/00; A61Q19/08; A61K; A61K31/00; A61K31/01; A23; A23B; A23B2/00; A23B2/70; A23B2/725; A23B2/729; A23B2/742; A23B2/75; A23B2/771; A61K31/33; A61K31/335; A61K31/35; A61K36/00; A61K36/16; A61K36/18; A61K36/185; A61K36/28; A61K36/286; A61K36/77; A61K36/82; A61K36/87; A61K47/00; A61K47/06; A61K47/24; A61K8/00; A61K8/18; A61K8/30; A61K8/31; A61K8/33; A61K8/35; A61K8/355; A61K8/49; A61K8/4973; A61K8/498; A61K8/67; A61K8/678; A61K8/96; A61K8/97; A61K8/9771; A61K8/9783; A61K8/9789; A61K9/00; A61K9/20; A61K9/48; A61P; A61P17/00; A61P3/00; A61P35/00; A61P39/00; A61P39/06; A61P9/00; A61P9/10; A61Q17/00; A61K2300/00; A61K2800/00; A61K2800/40; A61K2800/52; A61K2800/522

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 20 words
Pharmaceutical, foodstuff, dietetic or cosmetic compositions containing as the active principle a lipophilic antioxidant in combination with an hydrophilic antioxidant.
Claim 2
Dependent Claim 20 words
Compositions according to claim 1 wherein the lipohilic antioxidant is selected from the group of carotenoids, procarotenoids and derivatives thereof.
Claim 3
Dependent Claim 18 words
Compositions according to claim 2 wherein the lipophilic antioxidant is selected from vitamin E, β-carotene, lycopene, ubidecarenone, ubiquinol.
Claim 4
Dependent Claim 24 words
Compositions according to any one of claims 1-3 wherein the hydrophilic antioxidant is selected from the group of polyphenols of catechic or flavanolignane structure.
Claim 5
Dependent Claim 45 words
Compositions according to claim 4 wherein the hydrophilic antioxidant is selected from silymarin or one of the components thereof (silybin, silydianin, silychristin and isosilybin), proanthocyanidin A2, procyanidole oligomers extracted from Vitis vinifera , Camellia sinensis , Aesculus hippocastanum , Ginkgo biloba , Cardus marianum .
Claim 6
Dependent Claim 22 words
Compositions according to any one of claims 1-5 containing as excipients natural or synthetic phospholipids, including raw lecithins having different phospholipid contents.
Claim 7
Dependent Claim 22 words
Compositions according to any one of the above claims, in form of soft or hard gelatin capsules, tablets, suppositories or transdermal forms.

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