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EP0591980A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Leukocyte-removing filter device and system

Assignee: Asahi Kasei Medical Co Ltd
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Filing: 1993-10-07
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Granted: —
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Expires: 2013-10-07
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Abstract

Abstract Disclosed is a leukocyte-removing filter device (1) comprising (a) a casing (4) having an inlet (2) for blood and an outlet (3) for leukocyte-removed blood, which are both located in a top portion of the casing (4), and (b) a filter medium (5,5') disposed in the casing (4) so as to divide the internal space of the casing into an inlet-side chamber (7) communicated with the inlet (2) and an outlet-side chamber (7) communicated the outlet (3). By virtue of the locations of the inlet (2) and outlet (3) on the top portion of the filter device (4), the leukocyte-removing filter device (1) of the present invention is advantageous not only in that the filter device (1) can be fittedly and stably accommodated into a centrifuge cup together with a plurality of blood bags and circuit tubes connecting the filter device and blood bags, so that a centrifugation can be efficiently conducted without the danger of damaging the filter device and the blood bags, but also in that the operation of expelling the air from the filter by filling the filter with blood can be very readily conducted simply by allowing blood to flow into the filter without any additional burdensome operations. The leukocyte-removing system comprising the above-mentioned leukocyte-removing filter device is also disclosed.

Inventors

  • 👤 Takao Nishimura

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-29 10:26
CPC Classifications
A; A61; A61M; A61M1/00; A61M1/36; A61M1/3693; A61M1/02; A61M1/0209; A61M1/0218; A61M1/0222; A61M1/0227; A61M1/3621; A61M1/3627; A61M1/3633; A61M2202/00; A61M2202/04; A61M2202/0413; A61M2202/0439

Claims Analysis

Total Claims: 9
Claim 1
Independent Claim 106 words
A leukocyte-removing filter device comprising: (a) a flat casing comprising opposite flat main walls fluid-tightly connected by a side wall structure to define an internal space of said casing, said casing having a top and a bottom portion which are spaced apart vertically of said casing, said top portion having an inlet for blood and an outlet for leukocyte-removed blood, and (b) a filter medium comprising at least one filter material sheet extending in said internal space of the casing along said flat main walls to partition said internal space into an inlet-side chamber communicated with said inlet and an outlet-side chamber communicated with said outlet.
Claim 2
Dependent Claim 76 words
The filter device according to claim 1, wherein the casing has a central axis vertically extending from said top portion to said bottom portion, and the inlet opens in a direction along a first line and the outlet opens in a direction along a second line, the first and second lines each forming an angle with the central axis and each angle being independently not more than 90° inclusive of 0° relative to the central axis.
Claim 3
Dependent Claim 28 words
The filter device according to claim 2, wherein each of said inlet and said outlet opens in a direction substantially parallel to the central axis of the casing.
Claim 4
Dependent Claim 47 words
The filter device according to claim 2 , wherein said inlet and said outlet are positioned in a symmetrical relationship with respect to a plane containing the central axis of the casing and extending in parallel to the main wall on the side of said outlet-side chamber.
Claim 5
Dependent Claim 77 words
The filter device according to claim 1, wherein the overall outer surface of said casing is substantially free of convexo-concave portions and sharp projections, rendering smooth said overall outer surface, and wherein said casing has an inner volume of from 1 ml to 150 ml and has the following outer dimensional characteristics: a width of not more than 15 cm, a height of not more than 25 cm and a thickness of not more than 2 cm.
Claim 6
Dependent Claim 61 words
The filter device according to claim 1, wherein said outlet-side chamber does not discontinuously vary in horizontal cross-sectional area more than 10 % over all of the inner space of the outlet-side chamber from its inner bottom portion to its inner uppermost portion and wherein the inner uppermost portion of said outlet-side chamber decreases in horizontal cross-sectional area toward said outlet.
Claim 7
Dependent Claim 175 words
A leukocyte-removing system comprising: a leukocyte-removing filter device comprising: (a) a flat casing comprising opposite flat main walls fluid-tightly connected by a side wall structure to define an internal space of said casing, said casing having a top and a bottom portion which are spaced apart vertically of said casing, said top portion having an inlet for blood and an outlet for leukocyte-removed blood, and (b) a filter medium comprising at least one filter material sheet extending in said internal space of the casing along said flat main walls to partition said internal space into an inlet-side chamber communicated with said inlet and an outlet-side chamber communicated with said outlet, inlet connecting means fluid-tightly connected to the inlet for aseptically connecting a part preceding the leukocyte-removing filter device to said inlet, at least one satellite bag, and outlet connecting means for fluid-tightly directly connecting said outlet of the leukocyte-removing filter device to said at least one satellite bag, said outlet connecting means comprising a tube, wherein said leukocyte-removing system is entirely in an aseptic state.
Claim 8
Dependent Claim 37 words
The system according to claim 7, further having an anticoagulant-containing blood collection bag fluid-tightly connected to said inlet connecting means, and wherein said at least one satellite bag includes a plurality of satellite bags connected in series.
Claim 9
Dependent Claim 35 words
The system according to claim 7, further having an anticoagulant-containing blood collection bag fluid-tightly connected to said inlet connecting means and having at least one satellite bag fluid-tightly, aseptically connected to said blood collection bag.

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