EP0526102A1
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Drug delivery catheter
Assignee: Boston Scientific Scimed Inc
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Filing: 1992-07-23
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Granted: —
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Expires: 2012-07-23
Abstract
Abstract A drug delivery catheter with an inflatable blood flow lumen includes a flexible tubular shaft (30) and an inflatable balloon assembly (10,12,14,16) disposed at the distal end of the shaft. The catheter is inserted into a vessel with the balloon assembly in an un-inflated form and the balloon member is positioned at the treatment site and inflated. The balloon member in an inflated form defines a region or pocket (26) between the balloon assembly and the vessel wall which contains the drug separate from blood flow. Apertures (40) are provided within the balloon assembly to provide the drug to the containment pocket. Blood is allowed to flow through the center (24) of the inflated balloon assembly.
Inventors
- 👤 Cyril J. Schweich, Jr.
- 👤 Matthew M. Burns
- 👤 Kent D. Harrison
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 11:41
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/10; A61M25/1002; A61M16/00; A61M16/04; A61M16/0402; A61M16/0431; A61M16/0434; A61M16/0454; A61M16/0459; A61M16/0475; A61M16/0477; A61M16/0481; A61M2025/1043; A61M2025/105; A61M2025/1052; A61M2025/1072; A61M2025/1097
Claims Analysis
Total Claims: 27
Claim 1
Independent Claim
209 words
A drug delivery catheter for insertion into a vessel which contains a first fluid, the drug delivery catheter comprising: an elongated tubular member having a proximal end and a distal end; a drug lumen in fluid communication with the distal end of the tubular member for delivering a second fluid; an inflatable balloon assembly disposed at the distal end of the tubular member, the balloon assembly including an inflatable balloon member having an uninflated state and an inflated state, the balloon assembly having apertures in fluid communication with the drug lumen; the balloon assembly configured such that 1) when the balloon member is in an uninflated state, the first fluid in the vessel may flow around the balloon assembly, and 2) when the balloon member is in an inflated state, i) sections of the balloon member contact the vessel wall defining a containment pocket for containing the second fluid between the vessel wall and within the contacting sections of the balloon assembly, ii) the apertures are disposed in the containment region, and iii) a flow lumen is defined through the balloon member to allow the first fluid to flow through the balloon member; and an inflation lumen in fluid communication with the balloon member for inflating the balloon member.
Claim 2
Dependent Claim
209 words
A drug delivery catheter for insertion into a vessel which contains a first fluid, the drug delivery catheter comprising: an elongated tubular member having a proximal end and a distal end; a drug lumen in fluid communication with the distal end of the tubular member for delivering a second fluid; an inflatable balloon assembly disposed at the distal end of the tubular member, the balloon assembly including an inflatable balloon member having an uninflated state and an inflated state, the balloon assembly having apertures in fluid communication with the drug lumen; the balloon assembly configured such that 1) when the balloon member is in an uninflated state, the first fluid in the vessel may flow around the balloon assembly, and 2) when the balloon member is in an inflated state, i) sections of the balloon member contact the vessel wall defining a containment pocket for containing the second fluid between the vessel wall and within the contacting sections of the balloon assembly, ii) the apertures are disposed in the containment region, and iii) a flow lumen is defined through the balloon member to allow the first fluid to flow through the balloon member; and an inflation lumen in fluid communication with the balloon member for inflating the balloon member.
Claim 3
Dependent Claim
25 words
A drug delivery catheter as claimed in Claim 1 wherein the containment packet of the balloon assembly isolates the first fluid from the second fluid.
Claim 4
Dependent Claim
23 words
A drug delivery catheter as claimed in Claim 1 or Claim 2 wherein the inflation lumen and the drug lumen are the same.
Claim 5
Dependent Claim
28 words
A drug delivery catheter as claimed in Claim 1 or Claim 2 wherein the inflation lumen and the drug lumen are not in fluid communication with each other.
Claim 6
Dependent Claim
58 words
A drug delivery catheter as claimed in any one of the preceding claims wherein the balloon assembly comprises a first toroidal balloon, a second toroidal balloon disposed distally of the first toroidal balloon, and a cylindrical sheath connected between the first and second toroidal balloons, wherein the flow lumen is defined through the center of the cylindrical sheath.
Claim 7
Dependent Claim
24 words
A drug delivery catheter as claimed in Claim 5 wherein the diameter of the cylindrical sheath is less than the diameter of the balloons.
Claim 8
Dependent Claim
24 words
A drug delivery catheter as claimed in any one of the preceding claims further comprising a guide wire lumen for receiving a guide wire.
Claim 9
Dependent Claim
24 words
A drug delivery catheter as claimed in Claim 7 wherein the guide wire lumen runs substantially coaxially through the length of the tubular member.
Claim 10
Dependent Claim
51 words
A drug delivery catheter as claimed in any one of the preceding claims wherein the balloon assembly comprises a first cylindrical sheath, a second cylindrical sheath disposed coaxially within the first cylindrical sheath, the first and second cylindrical sheaths being sealed together at their ends to define an inflation space therebetween.
Claim 11
Dependent Claim
44 words
A drug delivery catheter as claimed in Claim 9 wherein the first and second cylindrical sheaths are intermittently sealed to one another at spaced intervals between the sealed ends of the sheaths and a plurality of containment pockets are defined between the sealed sections.
Claim 12
Dependent Claim
22 words
A drug delivery catheter as claimed in any one of the preceding claims wherein the apertures are disposed in the balloon member.
Claim 13
Dependent Claim
173 words
A drug delivery catheter for insertion into a vessel containing a first fluid, the drug delivery catheter comprising: an elongated tubular shaft having a distal end and a proximal end; a balloon assembly including a first toroidal-shaped balloon disposed at the distal end of the tubular shaft, a second toroidal-shaped balloon spaced proximally from the first toroidal-shaped balloon, and a cylindrical sheath attached to the first and second toroidal-shaped balloons, the sheath attached to the toroidal-shaped balloons at a section of the toroidal-shaped balloons radially inward of the outer diameter of the toroidal-shaped balloons, the balloon assembly configured such that when the toroidal-shaped balloons are inflated, the toroidal-shaped balloons contact the vessel wall thereby defining a containment pocket between the vessel wall, the tubular shaft, the toroidal-shaped balloons, and the sheath; an inflation lumen in the tubular shaft in fluid communication with the toroidal-shaped balloons; and a drug lumen in the tubular shaft in fluid communication with at least one aperture in the containment pocket for delivering a drug to the containment pocket.
Claim 14
Dependent Claim
173 words
A drug delivery catheter for insertion into a vessel containing a first fluid, the drug delivery catheter comprising: an elongated tubular shaft having a distal end and a proximal end; a balloon assembly including a first toroidal-shaped balloon disposed at the distal end of the tubular shaft, a second toroidal-shaped balloon spaced proximally from the first toroidal-shaped balloon, and a cylindrical sheath attached to the first and second toroidal-shaped balloons, the sheath attached to the toroidal-shaped balloons at a section of the toroidal-shaped balloons radially inward of the outer diameter of the toroidal-shaped balloons, the balloon assembly configured such that when the toroidal-shaped balloons are inflated, the toroidal-shaped balloons contact the vessel wall thereby defining a containment pocket between the vessel wall, the tubular shaft, the toroidal-shaped balloons, and the sheath; an inflation lumen in the tubular shaft in fluid communication with the toroidal-shaped balloons; and a drug lumen in the tubular shaft in fluid communication with at least one aperture in the containment pocket for delivering a drug to the containment pocket.
Claim 15
Dependent Claim
29 words
A drug delivery catheter as claimed in Claim 12 further comprising an inner shaft tube running substantially coaxially and longitudinally through the tubular shaft for receiving a guide wire.
Claim 16
Dependent Claim
26 words
A drug delivery catheter as claimed in Claim 12 or Claim 13 comprising a plurality of toroidal-shaped balloons disposed between the first and second toroidal-shaped balloons.
Claim 17
Dependent Claim
13 words
A drug delivery catheter as claimed in Claim 14 comprising four toroidal-shaped balloons.
Claim 18
Dependent Claim
29 words
A drug delivery catheter as claimed in Claim 12 comprising a third toroidal balloon adjacent the first toroidal-shaped balloon and a fourth toroidal-shaped balloon adjacent the second toroidal-shaped balloon.
Claim 19
Dependent Claim
22 words
A drug delivery catheter as claimed in any one of the preceding claims wherein the apertures are disposed in the tubular shaft.
Claim 20
Dependent Claim
174 words
A fluid delivery catheter for insertion into a vessel which contains a first fluid, the fluid delivery catheter comprising: an elongated tubular shaft having a proximal end and a distal end; a balloon assembly disposed at the distal end of the tubular shaft, the balloon assembly including an inflatable balloon member having an uninflated state and an inflated state; the balloon assembly configured such that 1) when the balloon member is in an uninflated state, the first fluid in the vessel may flow around the balloon assembly, and 2) when the balloon member is in an inflated state, sections of the balloon member contact the vessel wall defining a containment pocket for containing a second fluid between the vessel wall and within the contacting sections of balloon member, and a flow lumen is defined through the balloon member to allow the first fluid to pass through the balloon member; means for inflating the balloon member; and means for providing a second fluid to the containment pocket when the balloon is in an inflated state.
Claim 21
Dependent Claim
174 words
A fluid delivery catheter for insertion into a vessel which contains a first fluid, the fluid delivery catheter comprising: an elongated tubular shaft having a proximal end and a distal end; a balloon assembly disposed at the distal end of the tubular shaft, the balloon assembly including an inflatable balloon member having an uninflated state and an inflated state; the balloon assembly configured such that 1) when the balloon member is in an uninflated state, the first fluid in the vessel may flow around the balloon assembly, and 2) when the balloon member is in an inflated state, sections of the balloon member contact the vessel wall defining a containment pocket for containing a second fluid between the vessel wall and within the contacting sections of balloon member, and a flow lumen is defined through the balloon member to allow the first fluid to pass through the balloon member; means for inflating the balloon member; and means for providing a second fluid to the containment pocket when the balloon is in an inflated state.
Claim 22
Dependent Claim
56 words
A fluid delivery catheter as claimed in Claim 18 wherein the means for providing a second fluid to the containment pocket comprises a drug lumen provided through the tubular shaft, the drug lumen being in fluid communication with at least one aperature disposed in the distal end of the shaft or disposed in the balloon member.
Claim 23
Dependent Claim
208 words
A fluid delivery catheter for insertion into a vessel which contains a first fluid and for delivering a second fluid to a predetermined site in the vessel, the fluid delivery catheter comprising: an elongated tubular shaft having a proximal end and a distal end and having a diameter less that the vessel; a balloon assembly disposed at the distal end of the tubular shaft, the balloon assembly including a balloon member which may be inflated and collapsed, the balloon member when in a collapsed state having a diameter less than the diameter of the vessel, and when in an inflated state, sections of the balloon engage the vessel wall and an area of the balloon member inside of the engaging sections does not contact the vessel wall to define a containment pocket within the engaging section of the balloon member, and when in an inflated state, a flow lumen is defined through the balloon assembly to allow the first fluid to flow therethrough; an inflation lumen in fluid communication with the balloon member to provide an inflation fluid to the balloon member; and an fluid delivery lumen in fluid communication at least one aperture disposed in the containment pocket for delivering a second fluid to the containment pocket.
Claim 24
Dependent Claim
208 words
A fluid delivery catheter for insertion into a vessel which contains a first fluid and for delivering a second fluid to a predetermined site in the vessel, the fluid delivery catheter comprising: an elongated tubular shaft having a proximal end and a distal end and having a diameter less that the vessel; a balloon assembly disposed at the distal end of the tubular shaft, the balloon assembly including a balloon member which may be inflated and collapsed, the balloon member when in a collapsed state having a diameter less than the diameter of the vessel, and when in an inflated state, sections of the balloon engage the vessel wall and an area of the balloon member inside of the engaging sections does not contact the vessel wall to define a containment pocket within the engaging section of the balloon member, and when in an inflated state, a flow lumen is defined through the balloon assembly to allow the first fluid to flow therethrough; an inflation lumen in fluid communication with the balloon member to provide an inflation fluid to the balloon member; and an fluid delivery lumen in fluid communication at least one aperture disposed in the containment pocket for delivering a second fluid to the containment pocket.
Claim 25
Dependent Claim
30 words
A fluid delivery catheter as claimed in Claim 20 wherein the catheter is configured to fit in a blood vessel and further comprising lumen adapted to receive a guide wire.
Claim 26
Dependent Claim
144 words
A fluid delivery catheter for insertion into a vessel which contains a first fluid and for delivering a second fluid to a predetermined site in the vessel, the fluid delivery catheter comprising: an elongated tubular shaft having a proximal end and a distal end and having a diameter less that the vessel; a balloon assembly disposed at the distal end of the tubular shaft, the balloon assembly including a balloon member which may be inflated and collapsed, the balloon member including flow means for allowing the first fluid to flow through the balloon assembly when the balloon is inflated and containing means for containing a second fluid outside of the flow of the first fluid and in contact with the vessel when the balloon member is inflated; means for inflating the balloon member; and means for delivering a second fluid to the containing means.
Claim 27
Dependent Claim
144 words
A fluid delivery catheter for insertion into a vessel which contains a first fluid and for delivering a second fluid to a predetermined site in the vessel, the fluid delivery catheter comprising: an elongated tubular shaft having a proximal end and a distal end and having a diameter less that the vessel; a balloon assembly disposed at the distal end of the tubular shaft, the balloon assembly including a balloon member which may be inflated and collapsed, the balloon member including flow means for allowing the first fluid to flow through the balloon assembly when the balloon is inflated and containing means for containing a second fluid outside of the flow of the first fluid and in contact with the vessel when the balloon member is inflated; means for inflating the balloon member; and means for delivering a second fluid to the containing means.
References Cited (Backward Citations)
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