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EP0521605A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Biocompatible lubricious grafts

Assignee: Ioptex Research Inc
•
Filing: 1992-05-14
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Granted: —
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Expires: 2012-05-14
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Abstract

Abstract A composition suitable for photografting composed of a hydrophilic monomer and a hydrophobic monomer which is either a perfluoroacrylate or a perfluoromethacrylate, which may be used in the manufacture of articles intended to contact moist body surfaces.

Inventors

  • 👤 Cheng Li
  • 👤 Michael Colvin
  • 👤 Amitava Gupta

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-05 03:37
CPC Classifications
G; G02; G02B; G02B1/00; G02B1/04; G02B1/041; G02B1/043; A; A61; A61L; A61L29/00; A61L29/08; A61L29/085; A61L31/00; A61L31/08; A61L31/10; C; C09; C09D; C09D4/00

Claims Analysis

Total Claims: 18
Claim 1
Independent Claim 16 words
A polymerizable coating composition comprising a hydrophilic monomer and a hydrophobic monomer comprising perfluoroacrylate or perfluoromethacrylate.
Claim 2
Dependent Claim 19 words
A composition according to claim 1 wherein the hydrophilic monomer comprises acrylamide, hydroxyethylmethacrylate, hydroxyethyacrylate, hydroxypropylmethacrylate, hydroxypropylacrylate or vinyl pyrrolidone.
Claim 3
Dependent Claim 25 words
A composition according to claim 1 or claim 2 wherein the molar ratio of hydrophilic to hydrophobic monomer is from about 1:1 to about 1:5.
Claim 4
Dependent Claim 24 words
An article having a surface coated with a polymeric composition comprising residues derived from a hydrophilic monomer and residues derived from perfluoroacrylate or perfluoromethacrylate.
Claim 5
Dependent Claim 19 words
An article according to claim 4 in which the polymeric composition is grafted onto the surface of the article.
Claim 6
Dependent Claim 17 words
An article according to claim 4 or claim 5 wherein the flexible article is made of rubber.
Claim 7
Dependent Claim 12 words
An article according to claim 6 wherein the rubber is natural rubber.
Claim 8
Dependent Claim 11 words
An article according to claim 7 wherein rubber is partly vulcanized.
Claim 9
Dependent Claim 27 words
An article according to any one of claims 4 to 8 wherein the article is a surgical or examination glove, a catheter, a condom or a ureter.
Claim 10
Dependent Claim 18 words
An article according to claim 4 or claim 5 wherein the article is made from an acrylic resin.
Claim 11
Dependent Claim 11 words
An article according to claim 10 wherein the resin is polymethylmethacrylate.
Claim 12
Dependent Claim 20 words
An article according to claims 4, 10 or 11 in the form of a contact lens or an intraocular lens.
Claim 13
Dependent Claim 47 words
A process for the manufacture of articles having a coated surface which comprises coating said surface with a polymerizable composition comprising hydrophilic monomers and hydrophobic monomers and thereafter subjecting the composition to irradiation to polymerize the composition, which the hydrophobic monomers comprise a perfluoroacrylic or a perfluoromethacrylate.
Claim 14
Dependent Claim 13 words
A process according to claim 13 wherein the irradiation is ultraviolet light irradiation.
Claim 15
Dependent Claim 30 words
A solution suitable for photografting comprised of low molecular weight polymers of ethylene oxide terminated with one or two polymerizable groups and a photocuring inhibitor capable of absorbing ultraviolet light.
Claim 16
Dependent Claim 29 words
A solution suitable for photografting according to claim 15, in which the polymer of ethylene oxide has a molecular weight not less than 200 and not more than 5,000.
Claim 17
Independent Claim 72 words
A method of forming an article having a surface coated with a polymeric composition comprising residues derived from a hydrophilic monomer and residues derived from perfluoroacrylate or perfluoromethacrylate, comprising dipping said article into a solution suitable for photografting comprised of low molecular weight polymers of ethylene oxide terminated with one or two polymerizable groups and a photocuring inhibitor capable of absorbing ultraviolet light prior to subjecting the article to said ultraviolet light.
Claim 18
Dependent Claim 19 words
An intraocular lens comprised of an acrylic copolymer having a banded coating of the photografted solution of claim 16.

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