EP0507604A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Ionically crosslinked carboxyl-containing polysaccharides for adhesion prevention
Assignee: Lifecore Biomedical Inc
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Filing: 1992-04-03
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Granted: —
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Expires: 2012-04-03
Abstract
Abstract A method of reducing post-operative adhesion formation by topically applying an ionically crosslinked carboxyl-containing polysaccharide or a pharmacologically acceptable salt thereof, e.g. sodium hyaluronate crosslinked with ferric chloride, to a site of surgical trauma.
Inventors
- 👤 W. James Huang
- 👤 Douglas B. Johns
- 👤 Richard L. Kronenthal
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 23:01
CPC Classifications
A; A61; A61K; A61K45/00; A61K45/06; A61K31/00; A61K31/33; A61K31/395; A61K31/40; A61K31/70; A61K31/715; A61K31/716; A61K31/717; A61K31/722; A61K31/726; A61K31/728; A61P; A61P31/00; A61P31/02; A61P43/00
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
14 words
A composition comprising an ionically crosslinked carboxyl-containing polysaccharide or a pharmacologically acceptable salt thereof.
Claim 2
Dependent Claim
9 words
The composition of claim 1 further comprising a drug.
Claim 3
Dependent Claim
13 words
The composition of claim 2, wherein the drug is an adhesion prevention aid.
Claim 4
Dependent Claim
17 words
The composition of claim 3, wherein the adhesion prevention aid is a non-steroidal anti-inflammatory drug, preferably tolmetin.
Claim 5
Dependent Claim
15 words
The composition of claim 2, wherein the drug is an antibiotic or a growth factor.
Claim 6
Dependent Claim
33 words
The composition of any one of claims 1 to 5, wherein the carboxyl-containing polysaccharide is carboxymethyl cellulose, carboxymethyl chitin, hyaluronic acid or an alkali or alkaline earth metal salt of one of these.
Claim 7
Dependent Claim
15 words
The composition of claim 6, wherein the carboxyl-containing polysaccharide is hyaluronic acid or sodium hyaluronate.
Claim 8
Dependent Claim
24 words
The composition of claim 6 or claim 7, wherein the carboxyl-containing polysaccharide is cross-linked with ferric chloride, aluminium chloride, chromium sulphate or aluminium sulphate.
Claim 9
Dependent Claim
23 words
The composition of any one of claims 1 to 8, wherein the ionically crosslinked carboxyl-containing polysaccharide is sodium hyaluronate crosslinked with ferric chloride.
Claim 10
Dependent Claim
28 words
A topically-applicable composition for application to a site of surgical trauma for the prevention of adhesion comprising a composition according to any one of claims 1 to 9.
Claim 11
Dependent Claim
23 words
The composition of claim 10, which is topically-applicable directly to the site of surgical trauma in one application by injection through a syringe.
Claim 12
Dependent Claim
11 words
A drug delivery system comprising a composition according to claim 2.
Claim 13
Dependent Claim
19 words
Use of an ionically crosslinked carboxyl-containing polysaccharide in the production of a topically-applicable medicament for use in adhesion prevention.
References Cited (Backward Citations)
No citation records indexed.
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