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EP0504807A1 Expired / Lapsed EP ⏱️ 0.0 years remaining

Use of bis-(p-hydroxyphenylthio)methane derivatives to inhibit progressive development of insulin-dependent diabetes mellitus

Assignee: Aventis Pharmaceuticals Inc
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Filing: 1992-03-17
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Granted: —
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Expires: 2012-03-17
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Abstract

Abstract The present invention relates to a method of inhibiting the progressive development of insulin-dependent diabetes mellitus in a patient comprising administering to said patient an effective inhibitory amount of a compound of the formula wherein R₁, R₂, R₃ and R₄ are each independently a C₁-C₆ alkyl group.

Inventors

  • 👤 Keith M. Robinson
  • 👤 Richard L. Jackson
  • 👤 Eric W. Heineke

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-25 06:52
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/28; A61K31/29; A61K31/095; A61K31/10; A61P; A61P3/00; A61P3/08; A61P3/10

Claims Analysis

Total Claims: 3
Claim 1
Independent Claim 44 words
A method for the preparation of a pharmaceutical composition useful in inhibiting the progressive development of insulin-dependent diabetes mellitus comprising combining a compound of the formula wherein R₁, R₂, R₃ and R₄ are each independently a C₁-C₆ alkyl group with a pharmaceutically acceptable carrier.
Claim 2
Independent Claim 52 words
A method for the preparation of a pharmaceutical composition useful in inhibiting the destruction of insulin-secreting islet β-cells caused by the progressive development of insulin-dependent diabetes mellitus, comprising combining a compound of the formula wherein R₁, R₂, R₃ and R₄ are each independently a C₁-C₆ alkyl group with a pharmaceutically acceptable carrier.
Claim 3
Dependent Claim 12 words
A method of Claim 1 or 2 wherein the compound is bis(3,5-di-tertiarybutyl-4-hydroxyphenylthio)methane.

References Cited (Backward Citations)

EP0292660A2 Cited
EP0372542A2 Cited
US4959392A Cited

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