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EP0488218A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Process for preparing polymer particles

Assignee: United States Surgical Corp
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Filing: 1991-11-27
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Granted: —
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Expires: 2011-11-27
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Abstract

Abstract A process is provided for preparing particles of polymer by heating the polymer having an inherent viscosity not exceeding about 0.6 dl/g when measured at a temperature of about 30 DEG C in chloroform or hexafluoroisopropanol, dividing the heated polymer into particles, and then solidifying these particles such that substantially no fibers are formed among the particles.

Inventors

  • 👤 John Kennedy

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-24 20:14
CPC Classifications
C; C08; C08J; C08J3/00; C08J3/12; A; A61; A61F; A61F2/00; A61F2/02; A61F2/28; A61L; A61L27/00; A61L27/14; A61L27/18; B; B29; B29B; B29B9/00; B29B9/10; C08L; C08L23/00; C08L23/02; C08L23/10; C08L23/12; C08L27/00; C08L27/02; C08L27/12; C08L27/18; C08L67/00; C08L69/00; C08L77/00; C08L77/02; C08J2367/00; C08J2367/02

Claims Analysis

Total Claims: 13
Claim 1
Independent Claim 54 words
A process for preparing particles comprising: a) heating a polymer having an inherent viscosity not exceeding about 0.6 dl/g when measured at a temperature of about 30°C in chloroform or hexafluoroisopropanol; b) dividing the thus-heated polymer into particles; and c) solidifying the particles, such that substantially no fibers are formed among the solidified particles.
Claim 2
Dependent Claim 71 words
A process according to claim 1, wherein the polymer has an initial inherent viscosity above about 0.6 dl/g when measured at a temperature of about 30°C in chloroform or hexafluoroisopropanol, and further comprising: treating the polymer so that the viscosity of the polymer is reduced to a level not exceeding about 0.6 dl/g when measured at 30°C in chloroform or hexafluoroisopropanol and then heating the polymer in accordance with step (a).
Claim 3
Dependent Claim 31 words
A process according to claim 1 or 2 wherein steps (a)-(c) are carried out such that average particle size of the solidified particles ranges from about 0.1 to about 3 mm.
Claim 4
Dependent Claim 24 words
A process according to claim 1, 2 or 3 wherein the polymer is heated to a temperature ranging from about 60°C to about 300°C.
Claim 5
Dependent Claim 29 words
A process according to any one of the preceding claims wherein the polymer is derived from polyglycolic acid, glycolide, lactic acid, lactide, dioxanone, e-caprolactone, trimethylene carbonate, and mixtures thereof.
Claim 6
Dependent Claim 26 words
A process according to any one of claims 1 - 4, wherein the polymer is derived from nylon, polyester, polypropylene, polytetrafluoroethylene, polyethylene terephthalate, and mixtures thereof.
Claim 7
Dependent Claim 31 words
A process according to any one of the preceding claims wherein the polymer is divided by a method selected from extrusion through a capillary, spraying through a nozzle and rotary atomization.
Claim 8
Dependent Claim 34 words
A process according to any one of the preceding claims, wherein the particles are solidified by being introduced into liquid which is immiscible with the polymer and which freezes the particles on contact therewith.
Claim 9
Dependent Claim 22 words
A process according to any one of claims 1 to 7, wherein the polymer particles are solidified by falling freely through air.
Claim 10
Dependent Claim 17 words
Bioabsorbable particles having an average particle size within a range of from about 0.1 to 3 mm.
Claim 11
Dependent Claim 19 words
Particles as claimed in claim 11, with an average particle size ranging from about 0.3 to about 1 mm.
Claim 12
Dependent Claim 33 words
Particles as claimed in claim 10 or 11, derived from a polymer, wherein the polymer is derived from one of polyglycolic acid, glycolide, lactic acid, lactide, dioxanone, e-caprolactone, trimethylene carbonate, and mixtures thereof.
Claim 13
Dependent Claim 36 words
A bead having a size within the range of about 0.1 to about 3 mm, derived from a polymer, wherein the polymer is derived from one of nylon, polyester, polypropylene, polytetrafluoroethylene, polyethylene terephthalate, and mixtures thereof.

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