EP0443809A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Coated intraocular lens and coatings therefor
Assignee: Ioptex Research Inc
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Filing: 1991-02-19
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Granted: —
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Expires: 2011-02-19
Abstract
Abstract A coating material is produced useful for coating an intraocular lens having haptics secured thereto or integral therewith or for coating one or more of said haptics or for coating both which contains at least one substance to be released at a predetermined controlled rate into the human eye together with the coating material. The coating material is hydrophilic, compatible with the lens or haptics both onto which it is coated, is non-toxic to the human eye, and is biocompatible with the human eye. The coating is capable of delivering a desired effective amount of the at least one substance into the human eye over a predetermined period of time, together with a method of releasing a desired substance into the human eye by implanting into the human eye an intraocular lens having a coating as above described.
Inventors
- 👤 Michael Colvin
- 👤 Joanna Elizabeth Barnes
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-06 04:10
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/14; A61F2/16; A61F2/1613; A61F9/00; A61F9/0008; A61F9/0017; A61K; A61K9/00; A61K9/0012; A61K9/0048; A61K9/0051; A61L; A61L27/00; A61L27/28; A61L27/34; A61L27/50; A61L27/54; A61P; A61P27/00; A61P27/02; A61F2/0077; A61F2002/0081; A61F2002/1681; A61F2250/00; A61F2250/0058; A61F2250/0067; A61L2300/00; A61L2300/40; A61L2300/404; A61L2300/41; A61L2300/60; A61L2300/606
Claims Analysis
Total Claims: 25
Claim 1
Independent Claim
114 words
In accordance with the present invention there is provided an intraocular lens comprising a lens body and optionally two haptics either attached to the lens body or formed integrally therewith and having a coating on at least a portion of at least one surface of said lens, which coating comprises a coating material and a releasable pharmacologically active agent in which said coating material is hydrophilic, compatible with the lens body or haptics onto which it is coated, and is non-toxic to and biocompatible with the human eye and which the pharmacologically active agent is present in a pharmacologially effective amount and is capable of being released at a predetermined rate from said coating.
Claim 2
Dependent Claim
114 words
In accordance with the present invention there is provided an intraocular lens comprising a lens body and optionally two haptics either attached to the lens body or formed integrally therewith and having a coating on at least a portion of at least one surface of said lens, which coating comprises a coating material and a releasable pharmacologically active agent in which said coating material is hydrophilic, compatible with the lens body or haptics onto which it is coated, and is non-toxic to and biocompatible with the human eye and which the pharmacologically active agent is present in a pharmacologially effective amount and is capable of being released at a predetermined rate from said coating.
Claim 3
Dependent Claim
21 words
A lens according to claim 1 wherein said pharmacologically active agent is a therepeutic agent present in a therapeutically effective amount.
Claim 4
Dependent Claim
20 words
A lens according to claim 1 wherein said pharmacologically active agent is a diagnostic agent present in an effective amount.
Claim 5
Dependent Claim
21 words
A lens according to claim 1 wherein said pharmacologically active agent is an anti-inflammatory agent present in an anti-inflammatory effective amount.
Claim 6
Dependent Claim
21 words
Coating material according to claim 1 wherein said pharmacologically active agent is a anti-microbial agent present in an anti-microbially effective amount.
Claim 7
Dependent Claim
21 words
A lens according to claim 1 wherein said pharmacologically active agent is an anti-mycotic agent present in an anti-mycoticly effective amount.
Claim 8
Dependent Claim
21 words
A lens according to claim 1 wherein said pharmacologically active agent is an anti-viral agent present in an anti-virally effective amount.
Claim 9
Dependent Claim
21 words
A lens according to claim 1 wherein said pharmacologically active agent is an anti-fungal agent present in an anti-fungally effective amount.
Claim 10
Dependent Claim
20 words
A lens according to claim 1 wherein said pharmacologically active agent is an imnonosuppressive agent present an immunosuppressively effective amount.
Claim 11
Dependent Claim
19 words
A lens according to any one of the preceding claims wherein the coating material is a hydroxy propylmethyl cellulose.
Claim 12
Dependent Claim
20 words
A lens according to claim 10 wherein the coating material is a combination of hydroxy propylmethyl cellulose and vinyl alcohol.
Claim 13
Dependent Claim
23 words
A lens according to claim 11 wherein the hydroxy propylmethyl cellulose and vinyl alcohol are present in a ratio of 10:90 to 90:10.
Claim 14
Dependent Claim
17 words
A lens according to any one of claims 1 to 9 wherein the coating material is collagen.
Claim 15
Dependent Claim
21 words
A lens according to any one of the preceding claims wherein the coating comprises more than one layer of coating material.
Claim 16
Dependent Claim
25 words
A lens according to any one of the preceding claims wherein the coating is on at least a portion of the periphery of the lens.
Claim 17
Dependent Claim
23 words
A lens according to any one of the preceding claims wherein the coating is on at least one portion of one lens surface.
Claim 18
Dependent Claim
21 words
A lens according to any one of the preceding claims wherein the coating is on at least one of the haptics.
Claim 19
Dependent Claim
23 words
A lens according to any one of the preceding claims wherein the coating is on substantially all of one surface of the lens.
Claim 20
Dependent Claim
23 words
A lens according to any of the preceding claims wherein the coating is on substantially on all of both surfaces of the lens.
Claim 21
Dependent Claim
22 words
A lens according to any one of the preceding claims wherein the coating is on two different portions of the lens surface.
Claim 22
Dependent Claim
16 words
A lens according to claim 20 wherein the two coatings contain the same pharmacologically active agent.
Claim 23
Dependent Claim
14 words
A lens according to claim 20 wherein each coating contains different pharmacologically active agents.
Claim 24
Dependent Claim
71 words
The present invention also provides a coating composition for an intraocular lens comprising a coating material and a releasable pharmacologically active agent wherein said coating material is hydrophilic compatible with the portions of the lens to be coated and is non-toxic to and biocompatible with the human eye and wherein said pharmacologically effective amount and capable of being released at predetermined rate for said composition when coated onto said intraocular lens.
Claim 25
Dependent Claim
71 words
The present invention also provides a coating composition for an intraocular lens comprising a coating material and a releasable pharmacologically active agent wherein said coating material is hydrophilic compatible with the portions of the lens to be coated and is non-toxic to and biocompatible with the human eye and wherein said pharmacologically effective amount and capable of being released at predetermined rate for said composition when coated onto said intraocular lens.
References Cited (Backward Citations)
No citation records indexed.
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