EP0432199B1
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Composition for the treatment of erectile dysfunction
Assignee: Amsu Ltd
•
Filing: 1989-09-01
•
Granted: 1993-07-28
•
Expires: 2009-09-01
Abstract
Abstract Lipophilic active substance composition and its use in a new method of treating erectile dysfunction by administration thereof, optionally together with a hydrophilic vehicle and optionally an antibacterial agent into the urethra.
Inventors
- 👤 Nils G. Kock
- 👤 Gerhard Lycke
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-25 10:11
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/21; A61K31/557; A61K31/5575; A61K9/00; A61K9/0012; A61K9/0034; A61P; A61P13/00; A61P13/02; A61P15/00; A61P25/00; A61P25/02; A61P31/00; A61P31/04
Claims Analysis
Total Claims: 33
Claim 1
Independent Claim
34 words
A composition for the treatment of erectile dysfunction via urethra, comprising a lipophilic active substance selected from a-receptor blockers, vasoactive polypeptide, prostaglandins and nitroglycerine dispersed in a hydrophilic vehicle and optionally an antibacterial agent.
Claim 2
Dependent Claim
34 words
A composition for the treatment of erectile dysfunction via urethra, comprising a lipophilic active substance selected from a-receptor blockers, vasoactive polypeptide, prostaglandins and nitroglycerine dispersed in a hydrophilic vehicle and optionally an antibacterial agent.
Claim 3
Dependent Claim
16 words
Acomposition according to Claim 1, wherein the a-receptor blockers are selected from phentolamine, phenoxybenzamine and prazosine.
Claim 4
Dependent Claim
16 words
A composition according to Claim 2, comprising phentolamine in an amount of at least 10 mg.
Claim 5
Dependent Claim
17 words
A composition according to Claim 3, comprising phentolamine in an amount of 10-200 mg, preferably 50-60 mg.
Claim 6
Dependent Claim
16 words
A composition according to Claim 2, comprising phenoxybenzamine in an amount of at least 50 mg.
Claim 7
Dependent Claim
16 words
Acomposition according to Claim 5, comprising phenoxybenzamine in an amount of 50-300 mg, preferably 100-150 mg.
Claim 8
Dependent Claim
16 words
A composition according to Claim 1, comprising nitroglycerine in an amount of at most 5 mg.
Claim 9
Dependent Claim
17 words
A composition according to Claim 7, comprising nitroglycerine in an amount of 0.5-5 mg, preferably 0.5-1.5 mg.
Claim 10
Dependent Claim
28 words
A composition according to Claim 1, comprising the active substance and optionally hydrophilic vehicle and optionally an antibacterial agent in a volume of 1-6 ml, generally 2-3 ml.
Claim 11
Dependent Claim
30 words
A composition according to Claim 1, wherein the active substance is selected from at least 2 members of the group consisting of a-receptor blockers, vasoactive intestinal polypeptide, prostaglandins and nitroglycerine.
Claim 12
Dependent Claim
17 words
A composition according to Claim 1, wherein the active substance is selected from a-receptor blockers and nitroglycerine.
Claim 13
Dependent Claim
16 words
A composition according to any of Claims 10 and 11, wherein the a-receptor blocker is phentolamine.
Claim 14
Dependent Claim
16 words
A composition according to any of Claims 10 and 11, wherein the a-receptor blocker is phenoxybenzamine.
Claim 15
Dependent Claim
20 words
A composition according to any of Claims 10, 11 and 12, wherein the a-receptor blocker is both phentolamine and phenoxybenzamine.
Claim 16
Dependent Claim
31 words
A composition according to any of Claims 10 - 14, comprising the active substance in the amounts disclosed in Claims 3 - 8 and in the volume disclosed in Claim 9.
Claim 17
Dependent Claim
46 words
Use of a lipophilic active substance selected from a-receptor blockers, vasoactive intestinal polypeptide, prostaglandins and nitroglycerine, optionally together with a hydrophilic vehicle and optionally an antibacterial agent for the preparation of a medicament for the treatment of erectile dysfunction by adminstration via urethra to corpora cavernosa.
Claim 18
Dependent Claim
46 words
Use of a lipophilic active substance selected from a-receptor blockers, vasoactive intestinal polypeptide, prostaglandins and nitroglycerine, optionally together with a hydrophilic vehicle and optionally an antibacterial agent for the preparation of a medicament for the treatment of erectile dysfunction by adminstration via urethra to corpora cavernosa.
Claim 19
Dependent Claim
18 words
Use according to Claim 16 of a-receptor blockers selected from the group consisting of phentolamine, phenoxybenzamine and prazosine.
Claim 20
Dependent Claim
15 words
Use according to Claim 17 of phentolamine in an amount of at least 10 mg.
Claim 21
Dependent Claim
16 words
Use according to Claim 18 of phentolamine in an amount of 10-200 mg, preferably 50-60 mg.
Claim 22
Dependent Claim
15 words
Use according to Claim 17 of phenoxybenzamine in an amount of at least 50 mg.
Claim 23
Dependent Claim
16 words
Use according to Claim 20 of phenoxybenzamine in an amount of 50-300 mg, preferably 100-150 mg.
Claim 24
Dependent Claim
15 words
Use according to Claim 16 of nitroglycerine in an amount of at most 5 mg.
Claim 25
Dependent Claim
16 words
Use according to Claim 22 of nitroglycerine in an amount of 0.5-5 mg, preferably 0.5-1.5 mg.
Claim 26
Dependent Claim
27 words
Use according to Claim 16 of the active substance and optionally hydrophilic vehicle and optionally an antibacterial agent in a volume of 1-6 ml, generally 2-3 ml.
Claim 27
Dependent Claim
20 words
Use according to Claim 16 of at least 2 members from of a-receptor blockers, vasoactive intestinal polypeptide, prostaglandins and nitroglycerine.
Claim 28
Dependent Claim
18 words
Use according to Claim 16 and 25, wherein the active substance is selected from a-receptor blockers and nitroglycerine.
Claim 29
Dependent Claim
11 words
Use according to Claim 26, wherein the a-receptor blocker is phentolamine.
Claim 30
Dependent Claim
11 words
Use according to Claim 26, wherein the a-receptor blocker is phenoxybenzamine.
Claim 31
Dependent Claim
14 words
Use according to Claim 26, wherein the a-receptor blocker is both phentolamine and phenoxybenzamine.
Claim 32
Dependent Claim
29 words
Use according to any of Claims 25 to 29 of the active substance in the amounts disclosed in Claims 18 to 21 and the volume disclosed in Claim 24.
Claim 33
Dependent Claim
19 words
Use according to Claim 16, wherein the vehicle consists of e.g. macrogols and/or other fat-free cream or ointment bases.
References Cited (Backward Citations)
No citation records indexed.
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