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EP0430539A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Ocular implants

Assignee: Oculex Pharmaceuticals Inc
•
Filing: 1990-11-20
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Granted: —
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Expires: 2010-11-20
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Abstract

Abstract Ocular implants are formed so as to be insertable in the suprachoroid of the eye, preferably in the form of plaques 0.5 to 10 mm x 0.5 to 10 mm, and 0.25 to 1.0 mm thick. They are made from a pharmacologically acceptable biodegradable polymer, such as a polyester, incorporating an active agent for treating an eye condition, for example an anti-tumour agent.

Inventors

  • 👤 Vernon G. Wong

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-04 23:20
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0048; A61K9/0051; Y; Y02; Y02A; Y02A50/00; Y02A50/30

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 52 words
Use, in the preparation of an implant for insertion into the suprachoroid of the eye and incapable of bodily migration therefrom, to treat an eye condition therapeutically, of (i) an agent which is a drug, pharmaceutical agent or bacterial agent, and (ii) a pharmacologically acceptable polymer which is degradable in the eye.
Claim 2
Dependent Claim 52 words
Use, in the preparation of an implant for insertion into the suprachoroid of the eye and incapable of bodily migration therefrom, to treat an eye condition therapeutically, of (i) an agent which is a drug, pharmaceutical agent or bacterial agent, and (ii) a pharmacologically acceptable polymer which is degradable in the eye.
Claim 3
Dependent Claim 20 words
Use according to claim 1 in which the eye condition is a tumour and the agent is an anti-tumour agent.
Claim 4
Dependent Claim 24 words
Use according to claim 1 or claim 2, comprising forming the implant in the form of a plaque of said polymer, incorporating the agent.
Claim 5
Dependent Claim 26 words
Use according to claim 1 or claim 2, comprising forming the implant in the form of a microcapsule or microsphere of said polymer, incorporating the agent.
Claim 6
Dependent Claim 69 words
An implant for treating an eye disease comprising (i) an agent which is a drug, pharmaceutical agent or bacterial agent, and (ii) a pharmacologically acceptable polymer which is degradable in the eye, characterised by being in the form of a plaque capable of insertion into the suprachoroid of an eye, the plaque being 0.5 to 10 mm long, 0.5 to 10 mm wide, and 0.25 to 1.0 mm thick.
Claim 7
Dependent Claim 69 words
An implant for treating an eye disease comprising (i) an agent which is a drug, pharmaceutical agent or bacterial agent, and (ii) a pharmacologically acceptable polymer which is degradable in the eye, characterised by being in the form of a plaque capable of insertion into the suprachoroid of an eye, the plaque being 0.5 to 10 mm long, 0.5 to 10 mm wide, and 0.25 to 1.0 mm thick.
Claim 8
Dependent Claim 22 words
An implant according to claim 5 in which the agent is a bacterial agent selected from acid-fast bacilli and C. parvum .
Claim 9
Dependent Claim 15 words
An implant according to claim 5 in which the agent is methotrexate, vincristine or hydrocortisone.
Claim 10
Dependent Claim 22 words
An implant according to any one of claims 5 to 7 in which the polymer is a condensation polymer, preferably a polyester.
Claim 11
Dependent Claim 19 words
An implant according to claim 8 in which the polymer comprises a hydroxyaliphatic carboxylic acid monomer, preferably lactic acid.

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