EP0429438A2
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EP
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Bone repair using collagen
Assignee: Collagen Aesthetics Inc
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Filing: 1985-07-03
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Granted: —
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Expires: 2005-07-03
Abstract
Abstract A composition for repairing bone defects by use of suspensions containing purified atelopeptide, reconstituted fibrillar skin collagen is disclosed. The suspensions provide matrices for conductive growth of bone into the defect. The skin collagen may also be lyophilized and used in the form of mats or sheets. The formed reconstituted skin collagen are aspects of the invention.
Inventors
- 👤 Donald G. Wallace
- 👤 Karl A. Piez
- 👤 Thomas L. Smestad
- 👤 Rosa Armstrong
- 👤 Saeid Seyedin
- 👤 John M. Mcpherson
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-07 11:29
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/78; A; A61; A61F; A61F2/00; A61F2/02; A61F2/28; A61L; A61L27/00; A61L27/14; A61L27/22; A61L27/24; A61F2310/00; A61F2310/00005; A61F2310/00365; A61K; A61K38/00
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
13 words
A purified atelopeptide reconstituted fibrillar skin collagen preparation for use in bone repair.
Claim 2
Dependent Claim
15 words
A preparation according to claim 1 which is a lyophilized gel of the said collagen.
Claim 3
Independent Claim
33 words
A method of preparing a composition for effecting conductive repair of a bone defect in a mammal, which method comprises using a preparation of collagen which is purified atelopeptide reconstituted fibrillar skin collagen.
Claim 4
Dependent Claim
18 words
A method according to claim 3 wherein the purified atelopeptide reconstituted fibrillar skin collagen is a lyophilized gel.
Claim 5
Dependent Claim
17 words
The method according to claim 4 wherein the preparation of collagen has been formed into a sheet.
Claim 6
Dependent Claim
21 words
The method according to claim 3, claim 4 or claim 5 wherein the preparation of collagen is prepared from calf skin.
Claim 7
Independent Claim
21 words
The method according to any one of claims 3 to 6 wherein the preparation of collagen is substantially free of cross-linking.
Claim 8
Dependent Claim
20 words
A purified collagen preparation consisting essentially of a lyophilized reconstituted atelopeptide fibrillar skin collagen in the form of a sheet.
Claim 9
Dependent Claim
17 words
A purified collagen preparation according to claim 8 wherein the reconstituted collagen is substantially free of cross-linking.
Claim 10
Dependent Claim
34 words
A process for preparing lyophilized collagen mats suitable for use as bone implants which process comprises: (a) forming a suspension of purified atelopeptide reconstituted fibrillar skin collagen into sheets, and (b) lyophilizing the resultant.
References Cited (Backward Citations)
No citation records indexed.
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