Aqueous liquid formulations

Claim 1

An aqueous liquid formulation which comprises a compound of the formula : wherein each vicinal pair of substituents [R 1 and R 2 ], [R 3 and R 4 ], [R 5 and R 6 ] independently a) represent two vicinal hydrogen atoms, or b) form a second bond between the vicinal carbon atoms to which they are attached; in addition to its significance above, R 2 may represent an alkyl group; R 7 represents H, OH, protected hydroxy or O-alkyl, or in conjunction with R 1 it may represent =O; R 8 and R 9 independently represent H or OH; R 10 represents H, alkyl, alkyl substituted by one or more hydroxyl groups, alkenyl, alkenyl substituted by one or more hydroxyl groups, or alkyl substituted by = O; X represents 0, (H,OH), (H,H) or -CH 2 0-; Y represents O, (H,OH), (H,H), N-NR 11 R 12 or N-OR 13 ; R" and R 12 independently represent H, alkyl, aryl or tosyl; R1 3, R 14, R1 5, R 16, R 1 7, R 18 , R 19 , R 22 and R 23 independently represent H or alkyl; R 20 and R 21 independently represent O, or they may independently represent (R 20 a,H) and (R 21 a,H) respectively; R 20 a and R 21 a independently represent OH, O-alkyl or OCH 2 0CH 2 CH 2 0CH 3 or R 21 a is protected hydroxy; in addition, R 20 a and R 21 a may together represent an oxygen atom in an epoxide ring; n is 1, 2 or 3; in addition to their significances above, Y, R 10 and R 23 , together with the carbon atoms to which they are attached, may represent a 5- or 6-membered N-, S- or 0- containing heterocyclic ring, which may be saturated or unsaturated, and which may be substituted by one or more groups selected from alkyl, hydroxy, alkyl substituted by one or more hydroxyl groups, O-alkyl, benzyl and -CH 2 Se(C 6 H 5 ), or a pharmaceutically acceptable salt thereof and a surfactant.