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EP0426074A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Polymer mixtures useful in skin care

Assignee: Biomatrix Inc
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Filing: 1990-10-29
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Granted: —
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Expires: 2010-10-29
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Abstract

Abstract Binary polymer mixtures of albumin and glycosaminoglycan and ternary polymer mixtures of polyionic polypeptide and high molecular weight and highly charged polyanions are useful for managing skin including wrinkles or other irregularities. Aqueous compositions of the ternary mixtures have pH dependent phase change properties and provide skin activated films.

Inventors

  • 👤 Philip Arthur Band
  • 👤 Arminda Gloria Barbone
  • 👤 Errol Desmond Goddard
  • 👤 Adolf Leshchinger
  • 👤 Emmett Malone Partain Iii
  • 👤 Joseph Peter Pavlichko

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-09 03:52
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/64; A61K8/65; A61K8/72; A61K8/73; A61K8/735; A61P; A61P17/00; A61Q; A61Q19/00; A61Q19/08; C; C08; C08L; C08L89/00; A61K2800/00; A61K2800/40; A61K2800/59; A61K2800/594

Claims Analysis

Total Claims: 17
Claim 1
Independent Claim 92 words
An aqueous composition comprising water and a ternary polymer mixture of mutually distinct components selected from each of the following groups: (1) polyionic polypeptide; (2) first, high molecular weight, polyanion having a molecular weight of at least about 100,000; and (3) second, highly charged, polyanion containing acidic groups with a pK a of less than about 3 in an amount sufficient to provide an equivalent weight of such acidic groups of less than about 1,000; which mixture provides pH dependent phase change in aqueous solution due to interaction between the three components.
Claim 2
Dependent Claim 92 words
An aqueous composition comprising water and a ternary polymer mixture of mutually distinct components selected from each of the following groups: (1) polyionic polypeptide; (2) first, high molecular weight, polyanion having a molecular weight of at least about 100,000; and (3) second, highly charged, polyanion containing acidic groups with a pK a of less than about 3 in an amount sufficient to provide an equivalent weight of such acidic groups of less than about 1,000; which mixture provides pH dependent phase change in aqueous solution due to interaction between the three components.
Claim 3
Dependent Claim 33 words
The composition of claim 1 wherein the pH dependent phase change is evidenced by a decrease in light transmission through an aqueous solution of the mixture under acidic as compared to neutral conditions.
Claim 4
Dependent Claim 83 words
A skin care composition comprising car­rier, with or without suitable skin care additives, and a ternary polymer mixture of mutually distinct compo­nents selected from each of the following groups: (1) polyionic polypeptide; (2) first, high molecular weight, polyanion having a molecular weight of at least about 100,000; and (3) second, highly charged, polyanion containing acidic groups with a pK a of less than about 3 in an amount sufficient to provide an equivalent weight of such acidic groups of less than about 1,000.
Claim 5
Dependent Claim 83 words
A skin care composition comprising car­rier, with or without suitable skin care additives, and a ternary polymer mixture of mutually distinct compo­nents selected from each of the following groups: (1) polyionic polypeptide; (2) first, high molecular weight, polyanion having a molecular weight of at least about 100,000; and (3) second, highly charged, polyanion containing acidic groups with a pK a of less than about 3 in an amount sufficient to provide an equivalent weight of such acidic groups of less than about 1,000.
Claim 6
Dependent Claim 40 words
The composition of any one of claims 1-­3 wherein: (1) the polyionic polypeptide is protein; (2) the first or high molecular weight polyanion is polynucleotide or polycarboxylate; (3) the second or highly charged polyanion is poly­sulfate, polysulfonate, polynucleotide or poly­phosphate.
Claim 7
Dependent Claim 33 words
The composition of claim 4 wherein: (1) the polyionic polypeptide is albumin; (2) the high molecular weight polyanion is hyaluro­nan or derivatives thereof; and (3) the highly charged polyanion is polysulfate or polysulfonate.
Claim 8
Dependent Claim 17 words
The composition of claim 5 wherein the albumin is serum albumin and the polysulfate is dextran sulfate.
Claim 9
Dependent Claim 17 words
A skin care composition comprising car­rier, with or without suitable skin care additives, and albumin and glycosaminoglycan.
Claim 10
Dependent Claim 17 words
A skin care composition comprising car­rier, with or without suitable skin care additives, and albumin and glycosaminoglycan.
Claim 11
Dependent Claim 19 words
The composition of claim 7 wherein the albumin is serum albumin and the glycosaminoglycan is hyaluronan or derivatives thereof.
Claim 12
Dependent Claim 12 words
A film made from the composition of any one of claims 1-8.
Claim 13
Dependent Claim 17 words
A ternary polymer mixture comprising (1) albumin, (2) hyaluronan or derivatives thereof and (3) polysulfate or polysulfonate.
Claim 14
Dependent Claim 17 words
A ternary polymer mixture comprising (1) albumin, (2) hyaluronan or derivatives thereof and (3) polysulfate or polysulfonate.
Claim 15
Dependent Claim 19 words
The mixture of claim 10 wherein the al­bumin is serum albumin and the polysulfate or polysul­fonate is dextran sulfate.
Claim 16
Dependent Claim 19 words
A process for managing skin which com­prises applying a composition according to any one of claims 1-8 to skin.
Claim 17
Dependent Claim 33 words
A process for diminishing the appearance of wrinkles or other irregular areas of the skin which comprises applying a composition according to any one of claims 1-8 to such areas of the skin.

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