EP0423369A1
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Antithrombotic blood treating system
Assignee: Toray Industries Inc
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Filing: 1990-04-25
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Granted: —
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Expires: 2010-04-25
Abstract
Abstract An antithrombotic blood treating system comprising a combination of a permselective hollow fiber membrane containing a copolymer having a polyethylene oxide unit; a header having a blood-contacting surface coated with either a heparinized hydrophilic copolymer containing vinyl chloride as the constituent or a hydrophilic copolymer having a polyethylene oxide unit; a catheter; and a circuit. It becomes possible for the first time to conduct extracorporeal circulation for a long period of time without the necessity for internally administering heparin by imparting an antithrombotic property to the entire blood-contacting surface.
Inventors
- 👤 Ryozo Terada
- 👤 Kazumi Tanaka
- 👤 Tetsunosuke Kunitomo
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-22 23:03
CPC Classifications
B; B01; B01D; B01D71/00; B01D71/06; B01D71/76; B01D71/82; A; A61; A61L; A61L33/00; A61L33/0005; A61L33/0011; A61L33/0029; A61L33/06; A61L33/068; A61M; A61M1/00; A61M1/36; A61M1/3672; A61M1/3673; B01D63/00; B01D63/02; B01D63/021; B01D63/0233; B01D69/00; B01D69/08; B01D71/30; B01D71/301; B01D71/40; B01D71/401; B01D71/4011; B01D71/52; B01D71/521; B01D71/5211; A61M2202/00; A61M2202/04; A61M2202/0413; A61M2205/00; A61M2205/02; A61M2205/0238; B01D2313/00; B01D2313/13
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
56 words
An anti-thrombogenic blood treating system, comprising selectively permeable hollow yarn membranes made of a composition containing a copolymer with polyethylene oxide component, and headers, catheters and circuits respectively covered on the blood contact surface with a heparinized hydrophilic copolymer containing vinyl chloride as a component monomer or a hydrophilic copolymer with polyethylene oxide component, in combination.
Claim 2
Dependent Claim
28 words
An anti-thrombogenic blood treating system, according to claim 1, wherein the inner surfaces at the joints between the headers, catheters and circuits are free from any discrete protrusions.
Claim 3
Dependent Claim
59 words
An anti-thrombogenic blood treating system, according to claim 1, wherein the selectively permeable hollow yarn membranes are made of a composition containing a copolymer consisting of a monomer with a polyethylene oxide component of 5 or more in polymerization degree and a polymerizable carbon-carbon double bond in the same molecule and a monomer with a polymerizable carbon-carbon double bond.
Claim 4
Dependent Claim
47 words
An anti-thrombogenic catheter, with a catheter tube joined with a connector, comprising a layer of a heparinized hydrophilic copolymer containing vinyl chloride as a component monomer or a layer of a hydrophilic copolymer layer with polyethylene oxide component, being formed at least on its blood contact surface.
Claim 5
Dependent Claim
37 words
An anti-thrombogenic blood circuit, comprising a layer of a heparinized hydrophilic copolymer layer containing vinyl chloride as a component monomer or a layer of a hydrophilic copolymer with polyethylene oxide component, being formed on its inside surface.
Claim 6
Dependent Claim
35 words
An anti-thrombogenic header, comprising a layer of a heparinized hydrophilic copolymer containing vinyl chloride as a component monomer or a layer of a hydrophilic copolymer with polyethylene oxide component, being formed on its inside surface.
Claim 7
Dependent Claim
112 words
An anti-thrombogenic header, according to claim 6, wherein the header as a blood inlet port opened in the tangential direction of the inside space of the header; the height of the inside space on the inlet side is 1 to 5 times the inner diameter of the opened blood inlet port; the inner diameter of the inside space is larger than the outer diameter of a hollow yarn membrane bundle by 0 to 2 mm; the blood inlet port is in contact with the top of the inside space of the header; and the inside space has a conical protrusion at the center toward the opened end face of the hollow yarns.
References Cited (Backward Citations)
No citation records indexed.
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