EP0413492A2
Expired / Lapsed
EP
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Osteoprosthetic implant
Assignee: Osteotech Inc
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Filing: 1990-08-07
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Granted: —
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Expires: 2010-08-07
Abstract
Abstract At least a portion of the surface of an osteoprosthetic implant is provided with demineralized bone powder adhering thereto. Sorption of the bone particles is accompanied by rapid and deep bone in-growth which firmly anchors the prosthesis to the host bone repair site.
Inventors
- 👤 John W. Lyle
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-02 12:14
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/36; A61L27/3604; A61L27/3608; A61F; A61F2/00; A61F2/02; A61F2/30; A61F2/30767; A61L27/28; A61L27/3641; A61L27/3645; A61L27/365; A61L27/50; A61F2/32; A61F2/36; A61F2/3662; A61F2002/30001; A61F2002/30667; A61F2002/30677; A61F2310/00; A61F2310/00389; A61F2310/00958; A61L2430/00; A61L2430/02
Claims Analysis
Total Claims: 21
Claim 1
Independent Claim
21 words
An osteoprosthetic device possessing an osteogenic amount of demineralized bone powder adhering to at least a portion of the surface thereof.
Claim 2
Dependent Claim
21 words
An osteoprosthetic device possessing an osteogenic amount of demineralized bone powder adhering to at least a portion of the surface thereof.
Claim 3
Dependent Claim
23 words
The osteoprosthetic device of Claim 1 wherein the average particle size of the demineralized bone powder is from about 0.1 to about 1.2cm.
Claim 4
Dependent Claim
23 words
The osteoprosthetic device of Claim 1 wherein the average particle size of the demineralized bone powder is from about 0.2 to about 1cm.
Claim 5
Dependent Claim
16 words
The osteoprosthetic device of Claim 1 wherein the demineralized bone powder is derived from cortical bone.
Claim 6
Dependent Claim
33 words
The osteoprosthetic device of Claim 1 wherein the demineralized bone powder is incorporated into a coating of biocompatible, non-bioerodable binding agent adhering to at least a portion of the surface of the device.
Claim 7
Dependent Claim
22 words
The osteoprosthetic device of Claim 5 wherein the binding agent contains from about 5 to about 80 weight percent demineralized bone powder.
Claim 8
Dependent Claim
22 words
The osteoprosthetic device of Claim 1 wherein the binding agent contains from about 20 to about 60 weight percent demineralized bone powder.
Claim 9
Dependent Claim
16 words
The osteoprosthetic device of Claim 5 wherein the binding agent is an enamel or enamel-like material.
Claim 10
Dependent Claim
15 words
The osteoprosthetic device of Claim 5 wherein the binding agent is a synthetic organic polymer.
Claim 11
Dependent Claim
39 words
The osteoprosthetic device of Claim 9 wherein the polymer is selected from the group consisting of porous high density polyethylene, polypropylene, polysulfone, polyphenylenesulfide, polyacetal, thermoplastic polyester, polyamide, polyamideimide, thermoplastic polyimide, polyaryletherketone, polyarylethernitrile, aromatic polyhydroxyether, polyacrylate, polymethacrylate, polyacrylonitrile, and polyphenyleneoxide.
Claim 12
Dependent Claim
27 words
The osteoprosthetic device of Claim 5 wherein the binding agent contains at least one additional ingredient selected from the group consisting of reinforcing fiber and reinforcing particle.
Claim 13
Dependent Claim
76 words
The osteoprosthetic device of Claim 1 wherein the bone powder contains at least one additional ingredient selected from the group consisting of antiviral agent, antimicrobial agent, antibiotic agent, amino acid, peptide, vitamin, inorganic element, NAD, hormone, endocrine tissue, synthesizer, enzyme, polymer-cell scaffolding agent with parenchymal, angiogenic drug, polymeric drug carrier, collagen lattice, antigenic agent, cytoskeletal agent, biologically active component, mesenchymal agent, bone digestor, antitumor agent, cellular attractant, cellular attachment agent, immunosuppressant, nucleic acid and penetration enhancer.
Claim 14
Dependent Claim
80 words
The osteoprosthetic device of Claim 5 wherein the bone powder and/or the binding agent contains at least one additional ingredient selected from the group consisting of antiviral agent, antimicrobial agent, antibiotic agent, amino acid, peptide, vitamin, inorganic element, NAD, hormone, endocrine tissue, synthesizer, enzyme, polymer-cell scaffolding agent with parenchymal, angiogenic drug, polymeric drug carrier, collagen lattice, antigenic agent, cytoskeletal agent, biologically active component, mesenchymal agent, bone digestor, antitumor agent, cellular attractant, cellular attachment agent, immunosuppressant, nucleic acid and penetration enhancer.
Claim 15
Dependent Claim
21 words
The osteoprosthetic device of Claim 5 in which the thickness of the coating is from about 1 to about 50 mils.
Claim 16
Dependent Claim
21 words
The osteoprosthetic device of Claim 5 in which the thickness of the coating is from about 10 to about 40 mils.
Claim 17
Dependent Claim
19 words
The osteoprosthetic device of Claim 1 provided with an adhesion-promoting surface prior to application of the bone powder thereto.
Claim 18
Dependent Claim
19 words
The osteoprosthetic device of Claim 5 provided with an adhesion-promoting surface prior to application of the binding agent thereto.
Claim 19
Dependent Claim
20 words
The osteoprosthetic device of Claim 5 in which the surface of the coating is modified to increase its surface area.
Claim 20
Dependent Claim
16 words
The osteoprosthetic device of Claim 1 wherein the device is an orthopedic, dental or maxillofacial prosthesis.
Claim 21
Dependent Claim
16 words
The osteoprosthetic device of Claim 5 wherein the device is an orthopedic, dental or maxillofacial prosthesis.
References Cited (Backward Citations)
No citation records indexed.
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