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EP0408462A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Filter material for seizure of leukocytes and method for production thereof

Assignee: Terumo Corp
•
Filing: 1990-07-13
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Granted: —
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Expires: 2010-07-13
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Abstract

Abstract A leukocyte-seizing filter material formed of a three-dimensional reticularly continuous porous material comprising at least one polymeric substance and possessing an average pore diameter in the range of 1 to 60 mu m, a specific surface area in the range of 0.5 to 10 m<2>/g, a porosity in the range of 30 to 95%, a bubble point in the range of 0.08 to 0.40 kg/cm<2>, and a wall thickness in the range of 0.3 to 9.0 mm and allowed to be sterilized with high-pressure steam.

Inventors

  • 👤 Ken C/O Terumo Kabushiki Kaisha Tatebe
  • 👤 Yukio C/O Terumo Kabushiki Kaisha Seita
  • 👤 Shuzo C/O Terumo Kabushiki Kaisha Yamashita
  • 👤 Yasushi C/O Terumo Kabushiki Kaisha Nemoto
  • 👤 Yasuyuki C/O Terumo Kabushiki Kaisha Higuchi

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-28 15:51
CPC Classifications
B; B01; B01D; B01D39/00; B01D39/14; B01D39/16; B01D39/1669; B01D39/1676; A; A61; A61M; A61M1/00; A61M1/36; A61M1/3621; A61M1/3627; A61M1/3633; A61M2202/00; A61M2202/04; A61M2202/0413; A61M2202/0439

Claims Analysis

Total Claims: 28
Claim 1
Independent Claim 84 words
A leukocyte-seizing filter material formed of a three-dimensional reticularly continuous porous material comprising at least one polymeric substance and possessing an average pore diameter in the range of 1 to 60 µm, a specific surface area in the range of 0.5 to 10 m²/g, a porosity in the range of 30 to 95%, a bubble point in the range of 0.08 to 0.40 kg/cm², and a wall thickness in the range of 0.3 to 9.0 mm and allowed to be sterilized with high-pressure steam.
Claim 2
Dependent Claim 84 words
A leukocyte-seizing filter material formed of a three-dimensional reticularly continuous porous material comprising at least one polymeric substance and possessing an average pore diameter in the range of 1 to 60 µm, a specific surface area in the range of 0.5 to 10 m²/g, a porosity in the range of 30 to 95%, a bubble point in the range of 0.08 to 0.40 kg/cm², and a wall thickness in the range of 0.3 to 9.0 mm and allowed to be sterilized with high-pressure steam.
Claim 3
Dependent Claim 39 words
A filter material according to claim 1, wherein said polymeric substance is one member selected from the group consisting of polyurethane, polyvinylidene fluoride, polysulfones, polyether sulfones, polyesters, poly(meth)acrylates, butadiene-acrylonitrile copolymers, polyamides, polyether polyamide block copolymers, and ethylene-vinyl alcohol copolymers.
Claim 4
Dependent Claim 13 words
A filter material according to claim 1, wherein said polymeric substance is polyurethane.
Claim 5
Dependent Claim 65 words
A filter material according to claim 1, wherein said average pore diameter is in the range of 2 to 50 µm, said specific surface area in the range of 1 to 5 m²/g, said porosity in the range of 50 to 95%, said bubble point in the range of 0.13 to 0.27 kg/cm², and said wall thickness in the range of 0.5 to 5.0 mm.
Claim 6
Dependent Claim 97 words
A leukocyte-seizing filter material having formed on the surface of a porous substrate a layer of a three-­dimensional reticularly continuous porous material comprising at least one polymeric substance and possessing an average pore diameter in the range of 1 to 60 µm, a specific surface area in the range of 0.5 to 10 m²/g, a porosity in the range of 30 to 95%, a bubble point in the range of 0.08 to 0.30 kg/cm², a wall thickness in the range of 0.1 to 9.0 mm, and a surface pore ratio in the range of 6 to 90%.
Claim 7
Dependent Claim 97 words
A leukocyte-seizing filter material having formed on the surface of a porous substrate a layer of a three-­dimensional reticularly continuous porous material comprising at least one polymeric substance and possessing an average pore diameter in the range of 1 to 60 µm, a specific surface area in the range of 0.5 to 10 m²/g, a porosity in the range of 30 to 95%, a bubble point in the range of 0.08 to 0.30 kg/cm², a wall thickness in the range of 0.1 to 9.0 mm, and a surface pore ratio in the range of 6 to 90%.
Claim 8
Dependent Claim 39 words
A filter material according to claim 5, wherein said polymeric substance is one member selected from the group consisting of polyurethane, polyvinylidene fluoride, polysulfones, polyether sulfones, polyesters, poly(meth)acrylates, butadiene-acrylonitrile copolymers, polyamides, polyether polyamide block copolymers, and ethylene-vinyl alcohol copolymers.
Claim 9
Dependent Claim 13 words
A filter material according to claim 5, wherein said polymeric substance is polyurethane.
Claim 10
Dependent Claim 68 words
A filter material according to claim 5, wherein said average pore diameter is in the range of 2 to 50 µm, said specific surface area in the range of 1 to 5 m²/g, said bubble point in the range of 0.13 to 0.27 kg/cm², said wall thickness in the range of 0.3 to 5.0 mm, and said surface pore ratio in the range of 10 to 85 %.
Claim 11
Dependent Claim 14 words
A filter material according to claim 5, wherein said porous substrate is non-woven fabric.
Claim 12
Independent Claim 116 words
A method for the production of a leukocyte-seizing filter material comprising preparing a raw material composition comprising at least one polymeric substance, a good solvent for said polymeric substance, and at least one pore-forming agent soluble or swellable in a poor solvent compatible with said good solvent, extrusion molding said raw material composition in a prescribed shape with an extruding device, and then leading the extrusion molded composition into and immersing in a bath formed mainly of a poor solvent relative to said polymeric substance thereby gelling said extrusion molded composition and, at the same time, allowing said pore-forming agent to be dissolved into said good solvent and consequently effecting removal thereof from said shaped composition.
Claim 13
Independent Claim 116 words
A method for the production of a leukocyte-seizing filter material comprising preparing a raw material composition comprising at least one polymeric substance, a good solvent for said polymeric substance, and at least one pore-forming agent soluble or swellable in a poor solvent compatible with said good solvent, extrusion molding said raw material composition in a prescribed shape with an extruding device, and then leading the extrusion molded composition into and immersing in a bath formed mainly of a poor solvent relative to said polymeric substance thereby gelling said extrusion molded composition and, at the same time, allowing said pore-forming agent to be dissolved into said good solvent and consequently effecting removal thereof from said shaped composition.
Claim 14
Independent Claim 111 words
A method for the production of a leukocyte-seizing filter material comprising preparing a raw material composition comprising at least one polymeric substance, a good solvent for said polymeric substance, and at least one pore-forming agent soluble or swellable in a poor solvent compatible with said good solvent, applying a coating of said composition on the surface of a substrate, and leading the coated substrate into and immersing in a bath formed mainly of a poor solvent relative to said polymeric substance thereby gelling the applied coating and, at the same time, allowing said pore-forming agent to be dissolved into said good solvent and consequently effecting removal thereof from said coated substrate.
Claim 15
Independent Claim 111 words
A method for the production of a leukocyte-seizing filter material comprising preparing a raw material composition comprising at least one polymeric substance, a good solvent for said polymeric substance, and at least one pore-forming agent soluble or swellable in a poor solvent compatible with said good solvent, applying a coating of said composition on the surface of a substrate, and leading the coated substrate into and immersing in a bath formed mainly of a poor solvent relative to said polymeric substance thereby gelling the applied coating and, at the same time, allowing said pore-forming agent to be dissolved into said good solvent and consequently effecting removal thereof from said coated substrate.
Claim 16
Dependent Claim 41 words
A method according to claim 10 or claim 11, wherein said polymeric substance is one member selected from the group consisting of polyurethane, polyvinylidene fluoride, polysulfones, polyether sulfones, polyesters, poly(meth)acrylates, butadiene-acrylonitrile copolymers, polyamides, polyether polyamide block copolymers, and ethylene-vinyl alcohol copolymers.
Claim 17
Dependent Claim 15 words
A method according to claim 10 or claim 11, wherein said polymeric substance is polyurethane.
Claim 18
Dependent Claim 14 words
A method according to claim 12, wherein said pore-­forming agent is a water-soluble compound.
Claim 19
Dependent Claim 14 words
A method according to claim 12, wherein said pore-­forming agent is a water-soluble polymer.
Claim 20
Dependent Claim 34 words
A method according to claim 13, wehrein said pore-­forming agent is one member selected from the group consisting of polyvinyl alcohol, polyvinyl pyrrolidone, methyl cellulose, polyethers, polysaccharides, polyacrylic acid and salts thereof, and polyacrylamides.
Claim 21
Independent Claim 111 words
A method for the production of a leukocyte-seizing filter material comprising preparing a raw material composition comprising at least one polymeric substance, a good solvent for said polymeric substance, and at least one pore-forming agent soluble or swellable in a poor solvent compatible with said good solvent, applying a coating of said composition on the surface of a porous substrate, leading said coated substrate into and immersing in a bath containing a poor solvent and a good solvent relative to said polymeric substance thereby effecting solidification of said coating, and thereafter allowing said pore-forming agent to be dissolved into said good solvent and consequently effecting removal thereof from said coated substrate.
Claim 22
Independent Claim 111 words
A method for the production of a leukocyte-seizing filter material comprising preparing a raw material composition comprising at least one polymeric substance, a good solvent for said polymeric substance, and at least one pore-forming agent soluble or swellable in a poor solvent compatible with said good solvent, applying a coating of said composition on the surface of a porous substrate, leading said coated substrate into and immersing in a bath containing a poor solvent and a good solvent relative to said polymeric substance thereby effecting solidification of said coating, and thereafter allowing said pore-forming agent to be dissolved into said good solvent and consequently effecting removal thereof from said coated substrate.
Claim 23
Dependent Claim 38 words
A method according to claim 17, wherein said polymeric substance is one member selected from the group consisting of polyurethane, polyvinylidene fluoride, polysulfones, polyether sulfones, polyesters, poly(meth)acrylates, butadiene-acrylonitrile copolymers, polyamides, polyether polyamide block copolymers, and ethylene-vinyl alcohol copolymers.
Claim 24
Dependent Claim 12 words
A method according to claim 17, wherein said polymeric substance is polyurethane.
Claim 25
Dependent Claim 14 words
A method according to claim 17, wherein said pore-­forming agent is a water-soluble compound.
Claim 26
Dependent Claim 14 words
A method according to claim 20, wherein said pore-­forming agent is a water-soluble polymer.
Claim 27
Dependent Claim 34 words
A method according to claim 20, wherein said pore-­forming agent is one member selected from the group consisting of polyvinyl alcohol, polyvinyl pyrrolidone, methyl cellulose, polyethers, polysaccharides, polyacrylic acid and salts thereof, and polyacrylamides.
Claim 28
Dependent Claim 13 words
A method according to claim 17, wherein said porous substrate is non-woven fabric.

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