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EP0407992A1 Expired / Lapsed EP ⏱️ 0.0 years remaining

Method for determination of glucose concentration

Assignee: Arkray Inc
•
Filing: 1990-07-11
•
Granted: —
•
Expires: 2010-07-11
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Abstract

Abstract There is provided a method for the determination of a glucose concentration in a whole blood comprising steps of: obtaining two kinds of measured glucose concentrations in a whole blood sample to be measured by "Equilibrium Method" and a method selected from a group consisting of "First Differential Method" and "Second Differential Method", estimating a blood cell ratio to the whole blood from a ratio of one measured glucose concentration to the other on the basis of a previously established relation between the blood cell ratio and said two measured concentration ratio, whereby a conversion factor defined as a ratio of a true glucose concentration in the whole blood to one of the measured glucose concentrations by said three Methods is obtained, and converting said one measured glucose concentration with the obtained conversion factor to give the true glucose concentration as the glucose concentration in the whole blood.

Inventors

  • 👤 Katsumi Hamamoto
  • 👤 Kazunori Hirose

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-27 11:20
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/001; C12Q1/005; C12Q1/006; C12Q1/54; Y; Y10; Y10T; Y10T436/00; Y10T436/14; Y10T436/142222; Y10T436/143333; Y10T436/144444

Claims Analysis

Total Claims: 3
Claim 1
Independent Claim 145 words
A method for the determination of a glucose concentration in a whole blood comprising steps of: obtaining two kinds of measured glucose concentrations in a whole blood sample to be measured by "Equilibrium Method" and a method selected from a group consisting of "First Differential Method" and "Second Differential Method", estimating a blood cell ratio to the whole blood from a ratio of one measured glucose concentration to the other on the basis of a previously established relation between the blood cell ratio and said two measured concentration ratio, whereby a conversion factor defined as a ratio of a true glucose concentration in the whole blood to one of the measured glucose concentrations by said three Methods is obtained, and converting said one measured glucose concentration with the obtained conversion factor to give the true glucose concentration as the glucose concentration in the whole blood.
Claim 2
Independent Claim 145 words
A method for the determination of a glucose concentration in a whole blood comprising steps of: obtaining two kinds of measured glucose concentrations in a whole blood sample to be measured by "Equilibrium Method" and a method selected from a group consisting of "First Differential Method" and "Second Differential Method", estimating a blood cell ratio to the whole blood from a ratio of one measured glucose concentration to the other on the basis of a previously established relation between the blood cell ratio and said two measured concentration ratio, whereby a conversion factor defined as a ratio of a true glucose concentration in the whole blood to one of the measured glucose concentrations by said three Methods is obtained, and converting said one measured glucose concentration with the obtained conversion factor to give the true glucose concentration as the glucose concentration in the whole blood.
Claim 3
Dependent Claim 27 words
The process according to claim 1, wherein a hydrogen peroxide electrode is used in combination with a glucose oxidase in order to obtain the measured glucose concentrations.

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