EP0403458A1
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Novel polypeptides and their use
Assignee: BOMAN, HANS, G.
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Filing: 1990-06-06
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Granted: —
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Expires: 2010-06-06
Abstract
Abstract Polypeptides having the aminoacid sequence: H₂N-Ser-Try-Leu-Ser-Lys-Thr-Ala-Lys-Lys-Leu-Glu-Asn-Ser-Ala-Lys-Lys-Arg-Ile-Ser-Glu-Gly-Ile-Ala-Ile-Ala-Ile-Gln-Gly-Gly-Pro-Arg-COOH, and functional derivatives thereof; pharmaceutical ccompositions containing such polypeptides; and a method of inhibiting bacterial growth.
Inventors
- 👤 Hans G. Boman
- 👤 Viktor Mutt
- 👤 Hans Jörnvall
- 👤 Jong-Youn Lee
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 23:55
CPC Classifications
A; A61; A61K; A61K38/00; A61K38/16; C; C07; C07K; C07K14/00; C07K14/435; C07K14/46; C07K14/47; C07K14/4701; C07K14/4702; C07K14/4703; A61P; A61P31/00; A61P31/04
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
11 words
Polypeptides having the amino acid sequence: H₂N-Ser-Try-Leu-Ser-Lys-Thr-Ala-Lys-Lys-Leu-Glu-Asn-Ser-Ala-Lys-Lys-Arg-Ile-Ser-Glu-Gly-Ile-Ala-Ile-Ala-Ile-Gln-Gly-Gly-Pro-Arg-COOH, and functional derivatives thereof.
Claim 2
Dependent Claim
11 words
Polypeptides having the amino acid sequence: H₂N-Ser-Try-Leu-Ser-Lys-Thr-Ala-Lys-Lys-Leu-Glu-Asn-Ser-Ala-Lys-Lys-Arg-Ile-Ser-Glu-Gly-Ile-Ala-Ile-Ala-Ile-Gln-Gly-Gly-Pro-Arg-COOH, and functional derivatives thereof.
Claim 3
Dependent Claim
9 words
Polypeptides according to claim 1, in an underivatized form.
Claim 4
Dependent Claim
11 words
Polypeptides according to claim 1 in the form of an amide.
Claim 5
Dependent Claim
9 words
Polypeptides according to any preceding claim for therapeutic use.
Claim 6
Dependent Claim
11 words
Polypeptides according to claim 4 for use as an antibacterial agent.
Claim 7
Dependent Claim
32 words
A pharmaceutical composition containing as an active constituent of the polypeptide according to any of claims 1 to 3 in an antibacterially effective amount together with a pharmaceutically acceptable carrier or diluent.
Claim 8
Dependent Claim
21 words
A pharmaceutical composition according to claim 6, wherein said carrier or diluent is acceptable for oral, intramuscular, intravenous or subcutaneous administration.
Claim 9
Independent Claim
41 words
A method for inhibiting bacterial growth in animals, such as mammals including man, comprising the step of administering a polypeptide according to any of claims 1 to 3 or a composition according to claims 7 or 8 in an inhibitory amount.
Claim 10
Dependent Claim
27 words
A method according to claim 8 for intestinal use comprising oral administration of a composition according to claim 7 or 8 in a slow release dose form.
Claim 11
Dependent Claim
24 words
A method according to claim 8, comprising administration by injection of a composition according to claim 7 or 8 in an injectable dose form.
References Cited (Backward Citations)
No citation records indexed.
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