EP0396289A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Copolymer production
Assignee: Monsanto Co
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Filing: 1990-04-20
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Granted: —
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Expires: 2010-04-20
Abstract
Abstract A process for the synthesis of copolymers comprising 3-hydroxybutyrate (HB) and 3-hydroxyvalerate (HV) units by the cultivation of certain strains of Corynebacterium , and Rhodococcus , some of which are novel on a substrate containing e.g. glucose. The process can also be used to produce the previously unknown homopolymer of HV by using a substrate of valeric acid.
Inventors
- 👤 Alistair James Anderson
- 👤 David Byrom
- 👤 Edwin Alfred Dawes
- 👤 Geoffrey William Haywood
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-29 15:19
CPC Classifications
C; C12; C12P; C12P7/00; C12P7/62; C12P7/625; C12P7/40; C12P7/44; C08; C08G; C08G63/00; C08G63/02; C08G63/06; Y; Y10; Y10S; Y10S435/00; Y10S435/8215; Y10S435/822; Y10S435/829; Y10S435/843; Y10S435/872
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
95 words
A process for the synthesis of copolymers comprising HB monomer units and HV comonomer units characterised in that said process comprises aerobically cultivating a bacterium having the characteristics of at least one bacterium selected from the group consisting of Corynebacterium dioxydans ATCC 21766, Corynebacterium hydrocarboxydans ATCC 21767, Norcardia lucida NCIB 10980, Rhodococcussp. ATCC 19070 and Rhodococcus sp. NCIMB 40126 under growth limitation conditions in an aqueous medium comprising a substrate, said substrate comprising an HV component, wherein the NV component is an assimilable carbon compound that is metabolisable by Alcaligenes eutrophus NCIB 11599 to PHB.
Claim 2
Dependent Claim
95 words
A process for the synthesis of copolymers comprising HB monomer units and HV comonomer units characterised in that said process comprises aerobically cultivating a bacterium having the characteristics of at least one bacterium selected from the group consisting of Corynebacterium dioxydans ATCC 21766, Corynebacterium hydrocarboxydans ATCC 21767, Norcardia lucida NCIB 10980, Rhodococcussp. ATCC 19070 and Rhodococcus sp. NCIMB 40126 under growth limitation conditions in an aqueous medium comprising a substrate, said substrate comprising an HV component, wherein the NV component is an assimilable carbon compound that is metabolisable by Alcaligenes eutrophus NCIB 11599 to PHB.
Claim 3
Dependent Claim
23 words
A process as claimed in claim 1 wherein the number of HV comonomer units in the copolymer is at least 5 mol %.
Claim 4
Dependent Claim
36 words
A process as claimed in either claim 1 or claim 2 wherein the HV component is selected from the group consisting of glucose, fructose, acetic acid, lactic acid, butyric acid, succinic acid, molasses, and derivatives thereof.
Claim 5
Dependent Claim
81 words
A process for the synthesis of PHV homopolymer characterised in that said process comprises aerobically cultivating a bacterium having the characteristics of at least one bacterium selected from the group consisting of Corynebacterium dioxydans ATCC 21766, Corynebacterium hydrocarboxydans ATCC 21767, Norcardia lucida NCIMB 10980, Rhodococcus sp. ATCC 19070 and Rhodococcus sp. NCIMB 40126 under growth limitation conditions in an aqueous medium comprising a substrate, said substrate comprising an HV component, wherein the HV component is valeric acid or a derivative thereof.
Claim 6
Dependent Claim
81 words
A process for the synthesis of PHV homopolymer characterised in that said process comprises aerobically cultivating a bacterium having the characteristics of at least one bacterium selected from the group consisting of Corynebacterium dioxydans ATCC 21766, Corynebacterium hydrocarboxydans ATCC 21767, Norcardia lucida NCIMB 10980, Rhodococcus sp. ATCC 19070 and Rhodococcus sp. NCIMB 40126 under growth limitation conditions in an aqueous medium comprising a substrate, said substrate comprising an HV component, wherein the HV component is valeric acid or a derivative thereof.
Claim 7
Dependent Claim
45 words
A process as claimed in any one of claims 1 to 4 wherein the bacterium is at least one member of the group consisting of Corynebacterium dioxydans ATCC 21766, Corynebacterium hydrocarboxydans ATCC 21767, Norcardia lucida NCIB 10980, Rhodococcus sp. ATCC 19070 and Rhodococcus NCIMB 40126.
Claim 8
Dependent Claim
21 words
A process as claimed in any one of claims 1 to 5 where in the bacterium is Rhodococcus sp. NCIMB 40126.
Claim 9
Dependent Claim
14 words
A pure culture of Rhodococcus sp. NCIMB 40126, and mutants and variants derived therefrom.
Claim 10
Dependent Claim
14 words
A pure culture of Rhodococcus sp. NCIMB 40126, and mutants and variants derived therefrom.
Claim 11
Dependent Claim
4 words
A homopolymer of PHV.
Claim 12
Dependent Claim
4 words
A homopolymer of PHV.
References Cited (Backward Citations)
No citation records indexed.
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