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EP0389713B1 Expired / Lapsed EP ⏱️ 0.0 years remaining

Process for coating a substrate with a bioactive hydroxyapatite film

Assignee: Kyoto University
•
Filing: 1989-11-10
•
Granted: 1993-08-04
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Expires: 2009-11-10
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Abstract

No abstract record available.

Inventors

  • 👤 Tadashi Kokubo
  • 👤 Takao Yamamuro
  • 👤 Yoshio Abe

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-31 19:16
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/28; A61L27/30; A61L27/32; A61F; A61F2310/00; A61F2310/00389; A61F2310/00592; A61F2310/00796; Y; Y10; Y10S; Y10S623/00; Y10S623/92

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 67 words
A process for forming a hydroxyapatite film on a substrate, which process comprises arranging said substrate and a glass comprising CaO and SiO₂ as main components in a face-to-face relation at most 2 mm apart, and soaking the thus arranged substrate and glass in an aqueous solution substantially saturated or supersaturated with constituents of hydroxyapatite to form a bone-like hydroxyapatite film on a surface of the substrate.
Claim 2
Dependent Claim 37 words
A process according to claim 1, wherein said glass comprises 20 to 60 mol % CaO and 80 to 20 mol % SiO₂ and the total amount of CaO and SiO₂ is at least 70 mol %.
Claim 3
Dependent Claim 38 words
A process according to claim 1 or 2, wherein said aqueous solution contains Ca and P as a solute in amounts of 0.1 to 10 mM as Ca²⁺ ion and 0.1 to 50 mM as HPO₄²⁻ ion, respectively.
Claim 4
Dependent Claim 20 words
A process according to claim 1, 2 or 3, wherein said aqueous solution has a pH of 5 to 9.
Claim 5
Dependent Claim 22 words
A process according to any one of the preceding claims wherein said aqueous solution is at a temperature of 5 to 70°C.

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