EP0375520B1
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Cosmetic or pharmaceutical composition containing microspheres of polymers or lipids charged with at least one active substance
Assignee: Galderma Research and Development SNC
•
Filing: 1989-12-14
•
Granted: 1993-04-07
•
Expires: 2009-12-14
Abstract
Abstract The invention relates to a pharmaceutical or cosmetic composition for topical application, containing, in a suitable carrier, microspheres of polymers or of fatty substances filled with at least one active product, characterized in that at least 80% of the microspheres employed have a diameter of between 3 (my)m and 10 (my)m.
Inventors
- 👤 Hans Schaefer
- 👤 Francine Watts
- 👤 Christos Papantoniou
- 👤 Claude Mahieu
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-24 19:58
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/48; A61K9/50; A61Q; A61Q5/00; A61K8/00; A61K8/02; A61K8/0241; A61K8/18; A61K8/30; A61K8/33; A61K8/37; A61K8/375; A61K8/49; A61K8/494; A61K8/4953; A61K8/67; A61K8/671; A61K8/673; A61K8/675; A61K8/72; A61K8/84; A61K8/85; A61K9/14; A61K9/16; A61K9/1605; A61K9/1617; A61K9/1629; A61K9/1641; A61K9/1647; A61P; A61P17/00; A61P25/00; A61P25/24; A61P25/26; A61Q19/00; A61Q19/08; A61K2800/00; A61K2800/40; A61K2800/41; A61K2800/412; A61K2800/42; A61K2800/43; A61K2800/434; A61K2800/56; A61Q7/00
Claims Analysis
Total Claims: 33
Claim 1
Independent Claim
55 words
Pharmaceutical or cosmetic composition for topical application containing, in a suitable carrier, microspheres or polymers or of fatty substances with a melting point higher than 50°C filled with at least one active product, characterised in that at least 80 % by weight of the microspheres have a diameter of between 3 µm and 10 µm.
Claim 2
Dependent Claim
42 words
Composition according to Claim 1, characterised in that the polymer is chosen from the group consisting of styrene-based polymers, β-alanine-based polymers, polymers derived from acrylic or methacrylic acid, polyesters derived from lactic and/or glycolic acid, crosslinked proteins and proteins coagulated by heat.
Claim 3
Dependent Claim
14 words
Composition according to Claim 2, characterised in that the polymer is based on poly-β-alanine.
Claim 4
Dependent Claim
19 words
Composition according to Claim 2, characterised in that the polymer is a polyester derived from lactic and/or glycolic acid.
Claim 5
Dependent Claim
28 words
Composition according to Claim 1, characterised in that the fatty substance is chosen from the group consisting of fatty alcohols and derivatives of alcohols and of fatty acids.
Claim 6
Dependent Claim
20 words
Composition according to Claim 5, characterised in that the fatty substance has a melting point of between 50°C and 100°C.
Claim 7
Dependent Claim
68 words
Composition according to one of Claims 1 to 6, characterised in that the active product is chosen from the group consisting of agents for treating acne, skin-reinforcing agents, agents for treating hair, antifungals, astringents, antibiotics, antivirals, antihypertensives, antianginals, vasodilators, agents for treating cardiovascular disorders, antiinflammatory agents, antiallergens, antipruritics, growth factors of peptidic or proteinic nature, neurostimulants, antidepressant agents, natural compounds employed in neurobiological research, anaesthetics and hormone steroids.
Claim 8
Dependent Claim
27 words
Composition according to Claim 7, characterised in that it contains vitamin A, retinoic acid or one of its derivatives, or benzoyl peroxide, as agent for treating acne.
Claim 9
Dependent Claim
24 words
Composition according to Claim 7, characterised in that it contains minoxidil as antiloss or hair regrowth agent and S-carboxymethylcysteine or octopirox as antiseborrhoeic agent.
Claim 10
Dependent Claim
15 words
Composition according to Claim 7, characterised in that it contains nystatin or econazole as antifungal.
Claim 11
Dependent Claim
14 words
Composition according to Claim 7, characterised in that it contains aluminium chloride as astringent.
Claim 12
Dependent Claim
15 words
Composition according to Claim 7, characterised in that it contains erythromycin or tetracycline as antibiotic.
Claim 13
Dependent Claim
14 words
Composition according to Claim 7, characterised in that it contains vidarabine as antiviral agent.
Claim 14
Dependent Claim
14 words
Composition according to Claim 7, characterised in that it contains clonidine hydrochloride as antihypertensive.
Claim 15
Dependent Claim
13 words
Composition according to Claim 7, characterised in that it contains bradikynin as vasodilator.
Claim 16
Dependent Claim
26 words
Composition according to Claim 7, characterised in that it contains a peptide of the tachykinins group, in particular "substance P", as agent for treating cardiovascular disorders.
Claim 17
Dependent Claim
19 words
Composition according to Claim 7, characterised in that it contains aspirin or hydrocortisone or its derivatives as antiinflammatory agent.
Claim 18
Dependent Claim
14 words
Composition according to Claim 7, characterised in that it contains a chromoglycate as antiallergen.
Claim 19
Dependent Claim
15 words
Composition according to Claim 7, characterised in that it contains a phenothiazine derivative as antipruritic.
Claim 20
Dependent Claim
21 words
Composition according to Claim 7, characterised in that it contains the epidermic growth factor (EGF) as growth factor of peptidic nature.
Claim 21
Dependent Claim
15 words
Composition according to Claim 7, characterised in that it contains caffeine or theophylline as neurostimulant.
Claim 22
Dependent Claim
15 words
Composition according to Claim 7, characterised in that it contains a lithium salt as antidepressant.
Claim 23
Dependent Claim
18 words
Composition according to Claim 7, characterised in that it contains capsaicine as natural compound employed in neurobiological research.
Claim 24
Dependent Claim
15 words
Composition according to Claim 7, characterised in that it contains lidocaine or procaine as anaesthetic.
Claim 25
Dependent Claim
14 words
Composition according to Claim 7, characterised in that it contains nitroglycerine as antianginal agent.
Claim 26
Dependent Claim
24 words
Composition according to one of Claims 1 to 25, characterised in that the carrier is an aqueous carrier, lipophilic or otherwise, or an oil.
Claim 27
Dependent Claim
32 words
Composition according to one of Claims 1 to 26, characterised in that the carrier is in the form of liquid, of gel, of cream, of paste, of pomade or of dry powder.
Claim 28
Dependent Claim
24 words
Composition according to either of Claims 26 and 27, characterised in that the carrier is a nonlipophilic aqueous carrier consisting of a hydroalcoholic solution.
Claim 29
Dependent Claim
26 words
Composition according to either of Claims 26 and 27, characterised in that the carrier is a lipophilic aqueous carrier consisting of an aqueous solution of silicones.
Claim 30
Dependent Claim
22 words
Composition according to one of Claims 26 to 29, characterised in that the carrier is an aqueous carrier containing a gelling agent.
Claim 31
Dependent Claim
41 words
Composition according to either of Claims 26 and 27, characterised in that the carrier is an oil consisting of a triglyceride of C₈-C₁₀ fatty acids or a mixture of several of these triglycerides, of vaseline, of liquid paraffin or of lanolin.
Claim 32
Dependent Claim
38 words
Composition according to one of Claims 1 to 31, characterised in that it contains from 1 % to 40 % by weight of microspheres at least 80 % of which have diameters of between 3 and 10 µm.
Claim 33
Dependent Claim
25 words
Composition according to one of Claims 1 to 32, characterised in that it contains from 0.05 % to 60 % by weight of active product.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
Maintenance schedule is calculated for granted US utility patents.