EP0368247A2
Expired / Lapsed
EP
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Controlled release preparations
Assignee: Takeda Pharmaceutical Co Ltd
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Filing: 1989-11-07
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Granted: —
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Expires: 2009-11-07
Abstract
Abstract There is provided a matrix preparation produced by dispersing a pharmaceutically active ingredient into a matrix which is solid at ambient temperature and comprised of a fatty acid ester of a polyglycerol. The preparation has stable release-controlling ability, can be processed to fine granules, granules, capsules, tablets etc., and contributes to reduce the administration times of the active ingredient and side effects of the ingredient.
Inventors
- 👤 Yohko Akiyama
- 👤 Hidetoshi Horibe
- 👤 Minoru Yoshioka
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-03 07:19
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/20; A61K9/2072; A61K9/2077; A61K9/14; A61K9/16; A61K9/1605; A61K9/1617; A61K9/1629; A61K9/1635; A61K9/2081
Claims Analysis
Total Claims: 20
Claim 1
Independent Claim
32 words
A matrix preparation which comprises a pharmaceutically active ingredient dispersed into a matrix being solid at ambient temperature and consisting of a fatty acid ester of a polyglycerol or containing the same.
Claim 2
Dependent Claim
32 words
A matrix preparation which comprises a pharmaceutically active ingredient dispersed into a matrix being solid at ambient temperature and consisting of a fatty acid ester of a polyglycerol or containing the same.
Claim 3
Dependent Claim
33 words
Fine granules or granules which comprise a pharmaceutically active ingredient dispersed into a matrix being solid at ambient temperature and consisting of a fatty acid ester of a polyglycerol or containing the same.
Claim 4
Dependent Claim
33 words
Fine granules or granules which comprise a pharmaceutically active ingredient dispersed into a matrix being solid at ambient temperature and consisting of a fatty acid ester of a polyglycerol or containing the same.
Claim 5
Dependent Claim
15 words
A matrix preparation according to Claim 1, wherein microcrystalline wax is contained in the matrix.
Claim 6
Dependent Claim
16 words
Fine granules or granules according to Claim 2, wherein microcrystalline wax is contained in the matrix.
Claim 7
Dependent Claim
22 words
Fine granules or granules according to Claim 2 or 4, wherein the fine granules or granules are coated with a coating agent.
Claim 8
Dependent Claim
17 words
A capsule which comprises the fine granules or granules according to Claim 2 or 5 filled therein.
Claim 9
Dependent Claim
18 words
A tablet which is produced by tabletting the fine granules or granules according to Claim 2 or 5.
Claim 10
Dependent Claim
11 words
A tablet according to Claim 7, which contains a disintegrating agent.
Claim 11
Dependent Claim
42 words
Fine granules or granules which comprise a pharmaceutically active acidic ingredient and a water-insoluble or slightly water-soluble solid base dispersed into a matrix being solid at ambient temperature and consisting of a fatty acid ester of a polyglycerol or containing the same.
Claim 12
Dependent Claim
42 words
Fine granules or granules which comprise a pharmaceutically active acidic ingredient and a water-insoluble or slightly water-soluble solid base dispersed into a matrix being solid at ambient temperature and consisting of a fatty acid ester of a polyglycerol or containing the same.
Claim 13
Dependent Claim
37 words
Fine granules or granules which comprise a pharmaceutically active basic ingredient and an enteric substance dispersed into a matrix being solid at ambient temperature and consisting of fatty acid ester of a polyglycerol or containing the same.
Claim 14
Dependent Claim
37 words
Fine granules or granules which comprise a pharmaceutically active basic ingredient and an enteric substance dispersed into a matrix being solid at ambient temperature and consisting of fatty acid ester of a polyglycerol or containing the same.
Claim 15
Dependent Claim
17 words
Fine granules or granules according to Claim 9 or 10, which are coated with a coating agent.
Claim 16
Dependent Claim
18 words
A capsule which comprises the fine granules or granules according to Claim 9, 10 or 11 filled therein
Claim 17
Dependent Claim
19 words
A tablet which is produced by tabletting the fine granules or granules according to Claim 9, 10 or 11.
Claim 18
Dependent Claim
12 words
A tablet according to Claim 13, wherein a disintegrating agent is contained.
Claim 19
Dependent Claim
29 words
Use of a matrix being solid at ambient temperature and consisting of a fatty acid ester of a polyglycerol or containing the same for producing a controlled release preparation.
Claim 20
Dependent Claim
29 words
Use of a matrix being solid at ambient temperature and consisting of a fatty acid ester of a polyglycerol or containing the same for producing a controlled release preparation.
References Cited (Backward Citations)
No citation records indexed.
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