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EP0362910A2
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Synthetic peptides immunochemically reactive with HIV-antibodies
Assignee: Akzo NV
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Filing: 1989-08-22
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Granted: —
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Expires: 2009-08-22
Abstract
Abstract The invention concerns synthetic peptides which react immunochemically with antibodies directed against HIV. A method for the detection of HIV or anti-HIV in a test fluid, an immunochemical reagent and a test kit to be used when applying said detection methods belong to the present invention.
Inventors
- 👤 Jaap Goudsmit
- 👤 Robert Hans Meloen
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-25 00:19
CPC Classifications
C; C07; C07K; C07K7/00; C07K7/04; C07K7/08; C07K14/00; C07K14/005; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/569; G01N33/56983; G01N33/56988; C12; C12N; C12N2740/00; C12N2740/00011; C12N2740/10011; C12N2740/16011; C12N2740/16111; C12N2740/16122
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
41 words
Synthetic tetradecapeptide with aminoacid sequence as indicated in Figure 1 and fragments thereof which are immunochemically reactive with HIV-antibodies and a synthetic polypeptide, which contains the said tetradecapeptide as an essential constituent, or fragments thereof which are immunochemically reactive with HIV-antibodies.
Claim 2
Dependent Claim
41 words
Synthetic tetradecapeptide with aminoacid sequence as indicated in Figure 1 and fragments thereof which are immunochemically reactive with HIV-antibodies and a synthetic polypeptide, which contains the said tetradecapeptide as an essential constituent, or fragments thereof which are immunochemically reactive with HIV-antibodies.
Claim 3
Dependent Claim
11 words
Immunochemical reagent which contains a synthetic peptide according to Claim 1.
Claim 4
Dependent Claim
41 words
Synthetic heptacosapeptide with aminoacid sequence as indicated in Figure 2 and fragments thereof which are immunochemically reactive with HIV-antibodies and a synthetic polypeptide, which contains the said heptacosapeptide as an essential constituent, or fragments thereof which are immunochemically reactive with HIV-antibodies.
Claim 5
Dependent Claim
41 words
Synthetic heptacosapeptide with aminoacid sequence as indicated in Figure 2 and fragments thereof which are immunochemically reactive with HIV-antibodies and a synthetic polypeptide, which contains the said heptacosapeptide as an essential constituent, or fragments thereof which are immunochemically reactive with HIV-antibodies.
Claim 6
Dependent Claim
11 words
Immunochemical reagent which contains a synthetic peptide according to Claim 3.
Claim 7
Dependent Claim
41 words
Synthetic hentriacontapeptide with aminoacid sequence as indicated in Figure 3 and fragments thereof which are immunochemically reactive with HIV-antibodies and a synthetic polypeptide, which contains the said hentriacontapeptide as an essential constituent, or fragments thereof which are immunochemically reactive with HIV-antibodies.
Claim 8
Dependent Claim
41 words
Synthetic hentriacontapeptide with aminoacid sequence as indicated in Figure 3 and fragments thereof which are immunochemically reactive with HIV-antibodies and a synthetic polypeptide, which contains the said hentriacontapeptide as an essential constituent, or fragments thereof which are immunochemically reactive with HIV-antibodies.
Claim 9
Dependent Claim
11 words
Immunochemical reagent which contains a synthetic peptide according to Claim 5.
Claim 10
Dependent Claim
75 words
Method for the detection of antibodies directed against HIV in a test fluid, characterized in that an immunochemical reagent according to Claim 2, 4 or 6 is used, which reagent is brought into contact with the test fluid and the presence of immune complexes formed between the peptide and antibodies in the test fluid, which are reactive with the peptide, is detected and from this the presence of HIV-antibodies in the test fluid is determined.
Claim 11
Dependent Claim
61 words
Method for the detection of HIV in a test fluid, characterized in that an immunochemical reagent according to Claim 2, 4 or 6 is used, which reagent is brought into contact with the test fluid and the presence of immune complexes formed between peptide and anti-HIV is detected and from this the presence of HIV in the test fluid is determined.
Claim 12
Dependent Claim
31 words
Test kit to be used in an immuno-assay, at least containing one immunochemical reagent according to Claim 2, 4 or 6. Figure 1 Trp-Gly-Cys-Ser-Gly-Lys-Leu-Ile-Cys-Thr-Thr-Ala-Vai-Pro Figure 2 Ile-His-Ser-Leu-Ile-Glu-Glu-Ser-Gln-Asn-Gln-Gln-Glu-Lys-Asn-Glu-Gln-Glu-Leu-Leu-Glu-Leu-Asp-Lys-Trp-Ala-Ser Figure 3 Thr-His-Leu-Pro-Ile-Pro-Arg-Gly-Pro-Asp-Arg-Pro-Glu-Gly-Ile-Glu-Glu-Glu-G1y-Gly-Glu-Arg-Asp-Arg-Asp-Arg-Ser-I le-Arg-Leu-Val
References Cited (Backward Citations)
No citation records indexed.
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