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EP0339429A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Filter and dispenser vial and use thereof

Assignee: F Hoffmann La Roche AG
•
Filing: 1989-04-17
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Granted: —
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Expires: 2009-04-17
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Abstract

Abstract According to the invention, a piston fit filter and dispenser vial and method of using same is provided. The vial comprises a conventional filter (13), for example a piston fit serum filter closing the lower end of the vial and a closure having a pressure source fitting (25) closing off the upper end of the vial. The vial also includes a transfer tube having a first end inside the vial adjacent to the filter and a second end outside the vial. Filtrate, for example filtered blood serum, within the vial may be trans­ferred in predetermined aliquots to one or more awaiting sample containers from the vial by applying a predetermined volume of air from a pressure source via the pressure source fitting whereby displaced serum is forced up the transfer tube and out of the vial.

Inventors

  • 👤 David Vaughan Fansler
  • 👤 Ernest Arthur Knesel, Jr.
  • 👤 Daniel Raymond Shoemaker

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-09 17:49
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/483; G01N33/487; G01N33/49; G01N33/491; B; B01; B01D; B01D33/00; B01D33/01; B01L; B01L3/00; B01L3/02; B01L3/0289; B01L3/0293; Y; Y10; Y10T; Y10T436/00; Y10T436/25; Y10T436/25375; Y10T436/255; Y10T436/2575

Claims Analysis

Total Claims: 13
Claim 1
Independent Claim 142 words
A piston-type filter and dispenser vial for dispens­ing measured aliquots of filtrate, said vial comprising: a. a hollow shaft (10) including a side wall defining an interior, said hollow shaft having an upper end (16) and a lower end (15); b. a piston fit filter means (28) located in and closing the lower end (15) of the hollow shaft; said vial being characterized in that it further com­prises: c. a rigid transfer tube (17) having a first end (18) located within the interior of the hollow shaft and a second end (19) located outside the hollow shaft (10); and d. closure means (20) located in the upper end (16) of the hollow shaft (10) for closing the hollow shaft, said closure means including a fitting (21) for connecting the interior of the hollow shaft (10) with an external air pressure source (25).
Claim 2
Dependent Claim 142 words
A piston-type filter and dispenser vial for dispens­ing measured aliquots of filtrate, said vial comprising: a. a hollow shaft (10) including a side wall defining an interior, said hollow shaft having an upper end (16) and a lower end (15); b. a piston fit filter means (28) located in and closing the lower end (15) of the hollow shaft; said vial being characterized in that it further com­prises: c. a rigid transfer tube (17) having a first end (18) located within the interior of the hollow shaft and a second end (19) located outside the hollow shaft (10); and d. closure means (20) located in the upper end (16) of the hollow shaft (10) for closing the hollow shaft, said closure means including a fitting (21) for connecting the interior of the hollow shaft (10) with an external air pressure source (25).
Claim 3
Dependent Claim 34 words
A vial according to claim 1, wherein the first end (18) of the transfer tube (17) is located adjacent to said filter means (28) in the lower end (15) of the hollow shaft (10).
Claim 4
Dependent Claim 23 words
A vial according to claim 1, wherein the transfer tube (17) extends out through the side wall (14) of the hollow shaft (10).
Claim 5
Dependent Claim 33 words
A vial according to claim 3, wherein the first end (18) of the transfer tube (17) is located adjacent to said filter means (28) in the lower end (15) of the hollow shaft.
Claim 6
Dependent Claim 18 words
A vial according to claim 1, wherein the transfer tube (17) extends out through the closure means (20).
Claim 7
Dependent Claim 34 words
A vial according to claim 5, wherein the first end (18) of the transfer tube (17) is located adjacent to said filter means (28) in the lower end (15) of the hollow shaft (10).
Claim 8
Dependent Claim 24 words
A vial according to one of claims 3, 4, 5 or 6, wherein the transfer tube (17) is integral with the side wall (14).
Claim 9
Dependent Claim 17 words
A vial according to claim 1, wherein the fitting (21) is centrally located in the closure (20).
Claim 10
Dependent Claim 97 words
Use of a filter and dispenser vial according to claim 1 for providing measured aliquots of filtrate comprising steps of: a) inserting the vial into a test tube (22) containing a solution to be filtered to thereby cause filtrate to flow up inside the hollow shaft (10); b) connecting an external pressure source (25) to the fitting (21); and c) applying a predetermined volume of air to the inside of the hollow shaft from the external pressure source (25) to transfer a predetermined aliquot of filtrate out of the hollow shaft (10) through the transfer tube (17).
Claim 11
Dependent Claim 13 words
Use according to claim 9, wherein the external pressure source is a pipette.
Claim 12
Dependent Claim 108 words
Use of a filter and dispenser vial according to claim 1 for providing measured aliquots of filtered serum comprising the steps of: a. inserting the vial (1) into a test tube (22) containing a coagulated centrifuged whole blood sample (23) to thereby cause filtered serum (24) to flow up inside the hollow shaft (10); b. connecting an external pressure source (25) to the fitting (21); and c. applying a predetermined volume of the air to the inside of the hollow shaft (10) from the external pressure source (25) to transfer a predetermined aliquot of filtered serum (24) out of the hollow shaft (10) through the transfer tube (17).
Claim 13
Dependent Claim 13 words
Use according to claim 11, wherein the external pressure source is a pipette.

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