EP0330992A2
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EP
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Novel cyclobutane Derivatives, processes for their preparation and pharmaceutical compositions comprising them
Assignee: Nippon Kayaku Co Ltd
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Filing: 1989-02-23
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Granted: —
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Expires: 2009-02-23
Abstract
Abstract The invention is directed to cyclobutane derivatives represented by general formula (I): wherein A represents a hydrogen atom, a hydroxy group, an azido group or an amino group; and B represents a purine residue or a pyrimidine residue. The cyclobutane derivatives exhibit antiviral and antitumor activities and are thus expected as drugs.
Inventors
- 👤 Yuh-Ichiro Ichikawa
- 👤 Masanori Yamazaki
- 👤 Kaoru Matsuo
- 👤 Keiko Aoyama
- 👤 Fumiko Matsumura
- 👤 Yukihiro Nishiyama
- 👤 Kenichi Matsubara
- 👤 Takemitsu Nagahata
- 👤 Hiroo Hoshino
- 👤 Junichi Seki
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-30 07:37
CPC Classifications
C; C07; C07D; C07D239/00; C07D239/02; C07D239/24; C07D239/28; C07D239/46; C07D239/52; C07D239/54; C07D239/545; C07D239/553; C07D303/00; C07D303/02; C07D303/12; C07D303/16; C07D473/00
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
34 words
A cyclobutane derivative represented by general formula (I): wherein A represents a hydrogen atom, a hydroxy group, an azido group or an amino group; and B represents a purine residue or a pyrimidine residue.
Claim 2
Dependent Claim
34 words
A cyclobutane derivative represented by general formula (I): wherein A represents a hydrogen atom, a hydroxy group, an azido group or an amino group; and B represents a purine residue or a pyrimidine residue.
Claim 3
Dependent Claim
47 words
A cyclobutane derivative as claimed in claim 1, wherein said purine residue is: wherein R₁₀ represents a hydrogen atom, an amino group or a halogen atom and R₁₁ represents a hydrogen atom or an amino group, or, wherein R₁₂ represents a hydrogen atom or an amino group.
Claim 4
Dependent Claim
27 words
A cyclobutane derivative as claimed in claim 1, wherein said pyrimidine residue is: wherein X represents a hydrogen atom, a halogen atom or a lower alkyl group.
Claim 5
Dependent Claim
20 words
A cyclobutane derivative as claimed in claim 1, wherein A is a hydroxy group and B is a purine residue.
Claim 6
Dependent Claim
17 words
A cyclobutane derivative as claimed in claim 1, wherein A is a hydroxy group and B is:
Claim 7
Dependent Claim
18 words
A cyclobutane derivative represented by general formula (II): wherein R represents a hydrogen atom or a protective group.
Claim 8
Dependent Claim
18 words
A cyclobutane derivative represented by general formula (II): wherein R represents a hydrogen atom or a protective group.
Claim 9
Dependent Claim
23 words
A pharmaceutical composition containing cyclobutane derivatives of claim 1 as active ingredients, in association with a pharmaceutically acceptable, substantially non-toxic carrier or excipient.
Claim 10
Dependent Claim
10 words
A compound of claim 1 for use as a medicament.
Claim 11
Dependent Claim
17 words
A compound of claim 1 for use in treating or preventing diseases caused by virus or tumor.
Claim 12
Dependent Claim
22 words
Use of compounds of claim 1 for the manufacture of a medicament for therapeutic treatment of diseases caused by virus or tumor.
References Cited (Backward Citations)
No citation records indexed.
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