Novel indanoxyacetic acid derivatives and processes for preparing the same

Claim 1

A process for preparing an indanoxyacetic acid derivative of the formula: wherein R¹ is a lower alkyl group, a substituted or unsubstituted phenyl group, naphthyl group of a sulfur-containing heterocyclic group, R² is a hydroxy group or a protected hydroxy group, p is an integer of 2 or 3 and q is an integer of 0 or 1, or a salt thereof, which comprises the step or steps of: A) condensing a compound of the formula: wherein Y is amino group or a reactive residue, and R², p and q are the same as defined above, or a salt thereof with a sulfonyl compound of the formula: R¹SO₂X¹      (III) wherein R¹ is the same as defined above, and a) X¹ is hydroxy group or a reactive residue when Y is amino group or b) X¹ is amino group when Y is a reactive residue; or B) condensing a compound of the formula: wherein R¹ is the same as defined above, or a salt thereof with a compound of the formula: X²CH₂CO-[NH-(CH₂) p -CO] q -R²      (V) wherein X² is a reactive residue, and R², p and q are the same as defined above, to give the compound (I); or C) condensing a compound of the formula: wherein R¹ is the same as defined above, or a reactive derivative thereof with a compound of the formula: NH₂-(CH₂) p -COR²      (VI) wherein p and R² are the same as defined above, to give a compound of the formula: wherein R¹, R² and p are the same as defined above; or D) removing a protecting group from a compound of the formula: wherein R²¹ is a protected hydroxy group, and R², p and q are the same as defined above, to give a compound of the formula: wherein R¹, R², and q are the same as defined above; and E) if required, further converting the product into a salt thereof.