EP0324162A1
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Method of producing antibodies by genetic engineering
Assignee: Individual
•
Filing: 1988-12-24
•
Granted: —
•
Expires: 2008-12-24
Abstract
Abstract Functional antibody fragments can be produced in bacteria by coupling each of the genes for the individual chains to signal sequences which bring about the transport of the prepeptides through the cytoplasmic membrane, expressing the gene structures in a bacterium, and isolating the functional protein from the periplasmic space or the medium. The functional protein is advantageously isolated by affinity chromatography on an adsorbent which is loaded with the hapten or antigen, and elution with a solution of the hapten or antigen.
Inventors
- 👤 Andreas Dr. Plückthun
- 👤 Arne Skerra
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-29 22:14
CPC Classifications
C; C12; C12N; C12N15/00; C12N15/09; C12N15/11; C12N15/62; C12N15/625; C07; C07K; C07K16/00; C12P; C12P21/00; C07K2319/00; C07K2319/01; C07K2319/02; C07K2319/035
Claims Analysis
Total Claims: 0
No claims parsed yet. Click Sync Now above to re-index claims from Google Patents.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
Maintenance schedule is calculated for granted US utility patents.