EP0318377A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Enantiomeric derivatives of amino acids, process for their preparation and their pharmaceutical applications
Assignee: Bioprojet SC
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Filing: 1988-11-24
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Granted: —
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Expires: 2008-11-24
Abstract
Abstract The (R) or (S) isomer of acetorphan or N-/(acetylthiomethyl)-2-oxo-1-phenyl-3-propyl/(S) alanine methyl ester is prepared by splitting of racemic acetylthio-3-benzyl-2-propanoic acid by reaction with ephedrin, separation of the enantiomeric salt obtained, then freeing of the acid and coupling with the corresponding amino acid ester. The obtained preparations possess remarkable therapeutic activities and can notably be used as drugs.
Inventors
- 👤 Pierre Duhamel
- 👤 Lucette Duhamel
- 👤 Denis Danvy
- 👤 Jean-Christophe Plaquevent
- 👤 Bruno Giros
- 👤 Claude Gros
- 👤 Jean-Charles Schwartz
- 👤 Jeanne-Marie Lecomte
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-06 05:28
CPC Classifications
C; C07; C07C; C07C327/00; C07C327/20; C07C327/32; A; A61; A61P; A61P1/00; A61P1/08; A61P1/16; A61P13/00; A61P13/02; A61P15/00; A61P25/00; A61P25/04; A61P29/00; A61P43/00; A61P9/00; A61P9/12; C07B; C07B2200/00; C07B2200/07
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