EP0308066A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Promotion of host defense by systemic dsRNA treatment
Assignee: HEM Pharmaceuticals Corp
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Filing: 1988-08-12
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Granted: —
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Expires: 2008-08-12
Abstract
Abstract Parenterally administered systemic dsRNAS release host mediators into various compartmentalized biological fluids to combat various microorganisms, particularly viruses, thereby reducing the infectivity and spread of various organisms including those associated with various diseases such as those caused by venereal warts, herpes and HIV.
Inventors
- 👤 William A. Carter
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-07 13:54
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/70; A61P; A61P31/00; A61P31/12; A61P31/20; A61P31/22; C; C07; C07H; C07H21/00
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
36 words
The use of a dsRNA in the manufacture of parenteral medicament for treating a disease within a localised body compartment of a human or animal by activating the natural antiviral pathways and arming the immune system.
Claim 2
Dependent Claim
36 words
The use of a dsRNA in the manufacture of parenteral medicament for treating a disease within a localised body compartment of a human or animal by activating the natural antiviral pathways and arming the immune system.
Claim 3
Dependent Claim
16 words
The use of a dsRNA according to claim 1 wherein the disease is viral in nature.
Claim 4
Dependent Claim
19 words
The use of a dsRNA according to claim 2 wherein the virus is a member of the herpes family.
Claim 5
Dependent Claim
14 words
The use of a dsRNA according to claim 3 wherein the virus is cytomeglovirus.
Claim 6
Dependent Claim
19 words
The use of a dsRNA according to claim 2 wherein the virus is a member of the retrovirus family.
Claim 7
Dependent Claim
14 words
The use of a dsRNA according to claim 5 wherein the retrovirus is HIV.
Claim 8
Dependent Claim
15 words
The use of a dsRNA according to claim 1 wherein the disease is Alzheimer's disease.
Claim 9
Dependent Claim
49 words
The use of a dsRNA according to any preceding claim in which the mismatched dsRNA is a complex of polyinosinate and a polycytidylate containing from 1 in 5 to 1 in 30 uracil or guanidine bases, and is preferably I n .r(C₁₂₋₁₄,U) n or rI n . r(C₂₉,G) n
Claim 10
Dependent Claim
30 words
The use of a dsRNA according to any preceding claim whereon the localised body compartment is the person's body compartment fluid, saliva, tears, serous exudates, serous transudates and/or cerebrospinal fluid.
References Cited (Backward Citations)
No citation records indexed.
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