EP0285307A1
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System of measuring the corpuscular content of a fluid, e.g. blood
Assignee: Datex Ohmeda Inc
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Filing: 1988-03-22
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Granted: —
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Expires: 2008-03-22
Abstract
Abstract For measuring the corpuscular content of a fluid, in particular blood hematocrit, a system includes a catheter (101) whose tip (102) is inserted into a patient's bloodstream; the catheter includes one or more transmitting optical fibres (nn) for conducting light from a light source (DS1,DS2) to the tip and one or more receiving optical fibres (pp, oo) for receiving the light reflected by the corpuscles and transmitting it to a detector (244a, 244b, 244c) (not shown). The optical fibres together define two optical paths (although the paths can share a common optical fibre, e.g. fibre nn) and the relationship (e.g. the separation) between the transmitting optical fibre and the receiving optical fibre of one path is different to that of the other path and the system can include means to calculate blood hematocrit from the difference between the signals along the two paths.
Inventors
- 👤 Byron L. Moran
- 👤 Allan F. Willis
- 👤 Yitzhak Mendelson
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 12:35
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/145; A61B5/14535; A61B5/1455; A61B5/1459; G; G01; G01N; G01N21/00; G01N21/84; G01N21/85; G01N21/8507
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
242 words
A system for determining the corpuscular content of a fluid that contains a varying quantity of corpuscles, comprising: means, remote from such fluid, for emitting light; means, remote from such fluid, for detecting light; optical-fiber means for transmitting light from the remote light-emitting means via such fluid to the remote light-detecting means along two paths, each of said two paths including three segments: a first optical-fiber-means segment for directing light from the remote emitting means to such fluid, terminating in light-projecting means disposed adjacent to such remote fluid, a second optical-fiber-means segment, commencing in light-receiving means disposed adjacent to such fluid, for directing light from such fluid to the remote detecting means, and a third segment, between the light-projecting means and the light-receiving means, that includes scattering by such fluid and by such corpuscles therein; the first segment and its light-projecting means for one of the two paths having a first fixed, known geometrical relationship to the second segment and its light-receiving means for that one path; the first segment and its light-projecting means for the other of the two paths having a second fixed, known geometrical relationship to the second segment and its light-receiving means for that other path; said second geometrical relationship being different from said first geometrical relationship; and interpretation means, responsive to the light-detecting means, for comparing the light respectively transmitted along the two paths, to determine such quantity of corpuscles, taking into consideration said known geometrical relationships.
Claim 2
Independent Claim
242 words
A system for determining the corpuscular content of a fluid that contains a varying quantity of corpuscles, comprising: means, remote from such fluid, for emitting light; means, remote from such fluid, for detecting light; optical-fiber means for transmitting light from the remote light-emitting means via such fluid to the remote light-detecting means along two paths, each of said two paths including three segments: a first optical-fiber-means segment for directing light from the remote emitting means to such fluid, terminating in light-projecting means disposed adjacent to such remote fluid, a second optical-fiber-means segment, commencing in light-receiving means disposed adjacent to such fluid, for directing light from such fluid to the remote detecting means, and a third segment, between the light-projecting means and the light-receiving means, that includes scattering by such fluid and by such corpuscles therein; the first segment and its light-projecting means for one of the two paths having a first fixed, known geometrical relationship to the second segment and its light-receiving means for that one path; the first segment and its light-projecting means for the other of the two paths having a second fixed, known geometrical relationship to the second segment and its light-receiving means for that other path; said second geometrical relationship being different from said first geometrical relationship; and interpretation means, responsive to the light-detecting means, for comparing the light respectively transmitted along the two paths, to determine such quantity of corpuscles, taking into consideration said known geometrical relationships.
Claim 3
Dependent Claim
38 words
The system of claim 1, wherein: one of the optical-fiber-means path segments is used by both paths in common; and either the detecting means or the emitting means, but not both, is used by both paths in common.
Claim 4
Dependent Claim
78 words
The system of claim 1, wherein: the light-emitting means include one light source used by both paths in common; the light-detecting means include at least two different light detectors; one first optical-fiber-means segment is used by both paths in common to direct light from the one source to such fluid; and the second optical-fiber-means segments of the two paths are distinct from one another, each directing light from such fluid to a respective different one of the detectors.
Claim 5
Dependent Claim
61 words
The system of claim 3, wherein: the commonly used first optical-fiber-means segment includes just one optical fiber disposed to direct light from the light source to such fluid; and each respective second optical-fiber-means segment includes just one optical fiber, distinct from one another and distinct from the common optical fiber, disposed to direct light from such fluid to a respective detector.
Claim 6
Dependent Claim
68 words
The system of claim 1, wherein: the light-emitting means include at least two different light sources; the light-detecting means include one light detector used by both paths in common; the first optical-fiber-means segments of the two paths are distinct from one another, each directing light from a respective different one of the sources to such fluid, and one second optical-fiber-means segment is used by both paths in common.
Claim 7
Dependent Claim
68 words
The system of claim 5, wherein: the commonly used second optical-fiber-means segment includes just one optical fiber disposed to direct light from such fluid to the light detector; and each respective first optical-fiber-means segment includes just one respective optical fiber, disposed to direct light from a respective emitter to such fluid; the respective one optical fibers being distinct from one another and distinct from the common optical fiber.
Claim 8
Dependent Claim
119 words
The system of claim 1, also for use in measuring the chemical content of such fluid: wherein said light-emitting means emit light in a first particular wavelength band; and further comprising second light-emitting means that emit light in a second particular wavelength band; said first optical-fiber-means path segment also directing light in the second particular wavelength band from said second light-emitting means to such fluid; said second optical-fiber-means path segment also directing light in the second particular wavelength band from such fluid to the receiving means; and said interpretation means also comparing light in the two wavelength bands received by the light-detecting means, to determine the chemial constituency of the fluid taking into account said determined quantity of corpuscles.
Claim 9
Dependent Claim
119 words
The system of claim 2, also for use in measuring the chemical content of such fluid: wherein said light-emitting means emit light in a first particular wavelength band; and further comprising second light-emitting means that emit light in a second particular wavelength band; said first optical-fiber-means path segment also directing light in the second particular wavelength band from said second light-emitting means to such fluid; said second optical-fiber-means path segment also directing light in the second particular wavelength band from such fluid to the receiving means; and said interpretation means also comparing light in the two wavelength bands received by the light-detecting means, to determine the chemical constituency of the fluid taking into account said determined quantity of corpuscles.
Claim 10
Independent Claim
239 words
A system for determining the corpuscular content of a fluid that contains a varying quantity of corpuscles, comprising: a light source that is remote from such fluid; two light detectors that are both remote from such fluid; a first optical fiber having a proximal end outside and remote from such fluid and disposed to receive light from the source, and having a distal end, from which the proximal end is remote, that is adapted to be juxtaposed to such fluid so as to project the light into such fluid; second and third optical fibers, each having a distal end that is: in fixed, known geometric relationship to the distal end of the first fiber, and adapted to be juxtaposed to such fluid to receive a respective portion of the light projected by the first fiber, after scattering by such fluid; the second and third optical fibers also each having a proximal end that is remote from the respective distal end, and is outside and remote from such fluid, and is disposed to project its received portion of light to a respective one of the detectors; the geometric relationships of the second and third optical-fiber distal ends with the first optical-fiber distal end being different from one another; and interpretation means for comparing the light projected to the two detectors to determine such quantity of corpuscles, taking into consideration said known geometric relationships between the distal ends of the fibers.
Claim 11
Independent Claim
239 words
A system for determining the corpuscular content of a fluid that contains a varying quantity of corpuscles, comprising: a light source that is remote from such fluid; two light detectors that are both remote from such fluid; a first optical fiber having a proximal end outside and remote from such fluid and disposed to receive light from the source, and having a distal end, from which the proximal end is remote, that is adapted to be juxtaposed to such fluid so as to project the light into such fluid; second and third optical fibers, each having a distal end that is: in fixed, known geometric relationship to the distal end of the first fiber, and adapted to be juxtaposed to such fluid to receive a respective portion of the light projected by the first fiber, after scattering by such fluid; the second and third optical fibers also each having a proximal end that is remote from the respective distal end, and is outside and remote from such fluid, and is disposed to project its received portion of light to a respective one of the detectors; the geometric relationships of the second and third optical-fiber distal ends with the first optical-fiber distal end being different from one another; and interpretation means for comparing the light projected to the two detectors to determine such quantity of corpuscles, taking into consideration said known geometric relationships between the distal ends of the fibers.
Claim 12
Dependent Claim
190 words
The system of claim 9, also for use in measuring the chemical content of such fluid: wherein the light source emits light in a first particular wavelength band; and further comprising another light source that emits light in a second particular wavelength band; the proximal end of the first optical fiber also receiving light in the second particular wavelength band from said other light source; and the distal end of the first optical fiber also projecting light in the second particular wavelength band from said other light source into such fluid; and the distal ends of the second and third optical fibers also receiving respective portions of the light in the second particular wavelength band projected from the first optical fiber, after scattering from such fluid; and the proximal ends of the second and third optical fibers also projecting their received portions of light in the second particular wavelength band to the respective detectors; the interpretation means also comparing light in the two wavelength bands received by at least one of the two detectors, to determine the chemical constituency of the fluid taking into account said determined quantity of corpuscles.
Claim 13
Dependent Claim
47 words
The system of claim 9, wherein: the geometrical relationship of the first and second optical-fiber distal ends being that they are substantially parallel and side-by-side; the geometrical relationship of the first and third optical-fiber distal ends being that they are substantially parallel and separated from one another.
Claim 14
Dependent Claim
37 words
The system of claim 11: also comparing a solid spacer element; and wherein the first and third optical-fiber distal ends are separated from one another by the second optical-fiber distal end and by the solid spacer element.
Claim 15
Independent Claim
235 words
A system for determining the corpuscular content of a fluid that contains a varying quantity of corpuscles, comprising: two light sources that are both remote from such fluid; one light detector that is remote from such fluid; a first optical fiber having a distal end adapted to be juxtaposed to such fluid so as to receive light scattered from such fluid, and having a proximal end that is remote from the distal end and is outside and remote from such fluid and disposed to project the received light to the remote detector; second and third optical fibers, each: having a proximal end outside and remote from such fluid and disposed to receive respective light from a respective one of the remote sources, and having a distal end, from which the respective proximal end is remote, that is in fixed, known geometric relationship to the distal end of the first fiber; the distal ends of the second and third optical fibers being adapted for juxtaposition to such fluid to project into such fluid the light respectively received from the respective remote source; the geometric relationships of the second and third optical-fiber distal ends with the first optical-fiber distal end being different from one another; and interpretation means for comparing the light projected to the remote detector to determine such quantity of corpuscles, taking into consideration said known geometric relationships between the distal ends of the fibers.
Claim 16
Independent Claim
235 words
A system for determining the corpuscular content of a fluid that contains a varying quantity of corpuscles, comprising: two light sources that are both remote from such fluid; one light detector that is remote from such fluid; a first optical fiber having a distal end adapted to be juxtaposed to such fluid so as to receive light scattered from such fluid, and having a proximal end that is remote from the distal end and is outside and remote from such fluid and disposed to project the received light to the remote detector; second and third optical fibers, each: having a proximal end outside and remote from such fluid and disposed to receive respective light from a respective one of the remote sources, and having a distal end, from which the respective proximal end is remote, that is in fixed, known geometric relationship to the distal end of the first fiber; the distal ends of the second and third optical fibers being adapted for juxtaposition to such fluid to project into such fluid the light respectively received from the respective remote source; the geometric relationships of the second and third optical-fiber distal ends with the first optical-fiber distal end being different from one another; and interpretation means for comparing the light projected to the remote detector to determine such quantity of corpuscles, taking into consideration said known geometric relationships between the distal ends of the fibers.
Claim 17
Dependent Claim
165 words
The system of claim 13, also for use in measuring the chemical content of such fluid: wherein the light sources emit light in a first particular wavelength band; and further comprising other light sources that emit light in a second particular wavelength band; the proximal ends of the second and third optical fibers also receiving respective light in the second particular wavelength band from the respective sources; and the distal ends of the second and third optical fibers also projecting respective light in the second particular wavelength band into such fluid; the distal end of the first optical fiber also receiving light in the second particular wavelength band scattered from such fluid; and the proximal end of the first optical fiber also projecting light in the second particular wavelength band to the detector; and the interpretation means also comparing light in the two wavelength bands received by the detector, to determine the chemical constituency of the fluid taking into account said determined quantity of corpuscles.
Claim 18
Dependent Claim
47 words
The system of claim 13, wherein: the geometrical relationship of the first and second optical-fiber distal ends being that they are substantially parallel and side-by-side; the geometrical relationship of the first and third optical-fiber distal ends being that they are substantially parallel and separated from one another.
Claim 19
Dependent Claim
37 words
The system of claim 15: also comprising a solid spacer element; and wherein the first and third optical-fiber distal ends are separated from one another by the second optical-fiber distal end and by the solid spacer element.
References Cited (Backward Citations)
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