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EP0284039A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Slow-release pharmaceutical composition

Assignee: Chugai Pharmaceutical Co Ltd
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Filing: 1988-03-23
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Granted: —
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Expires: 2008-03-23
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Abstract

Abstract Slow-release pharmaceutical compositions which comprise at least one of the following: adenine, cystine and tyrosine in combination with at least one pharmaceutically active substance are disclosed. The slow-release pharmaceutical compositions which may be tablets, granules implants, capsules, troches etc., can either slowly release their active substances over time or release the active substances at a predetermined time after their administration. The slow-release pharmaceutical composition may be used with practically all types of drugs irrespective of whether they are water-soluble or slightly water-soluble, including hypotensives, antipyretic analgesic antiinflammatories, immunoregulators, adrenocortical hormones, antidiabetic agent, vasodilators, cardiotonics, antiarrhythmic agents, anti-arteriosclerotic agents, and antidotes.

Inventors

  • 👤 Yoshimitsu Iida

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-24 22:59
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/20; A61K9/0012; A61K9/0053; A61K9/0065; A61K47/00; A61K47/06; A61K47/16; A61K47/18; A61K47/183; A61K47/20; A61K47/22; A61K9/14; A61K9/16; A61K9/1605; A61K9/1617; A61K9/2004; A61K9/2013; A61K9/2072; A61K9/2086; A61K9/209; A61K9/48; A61K9/50; A61K9/5005; A61K9/5015; A61K9/0019; A61K9/0024; A61K9/0056

Claims Analysis

Total Claims: 13
Claim 1
Independent Claim 25 words
A slow-release pharmaceutical composition which comprises at least one of the following: adenine, cystine and tyrosine in combination with at least one pharmaceutically active substance.
Claim 2
Dependent Claim 25 words
A slow-release pharmaceutical composition which comprises at least one of the following: adenine, cystine and tyrosine in combination with at least one pharmaceutically active substance.
Claim 3
Dependent Claim 26 words
A slow-release pharmaceutical composition according to Claim 1 wherein the pharmaceutically active substance is a slightly soluble drug with a solubility of no more than 0.1%.
Claim 4
Dependent Claim 29 words
A slow-release pharmaceutical composition according to Claim 2 wherein the slightly soluble drug is in the form of particles having an average size of no more than 10 µm.
Claim 5
Dependent Claim 20 words
A slow-release pharmaceutical composition according to Claim 3 which further contains hydroxypropyl cellulose of low substitution degree and hydroxypropyl cellulose.
Claim 6
Dependent Claim 30 words
A slow-release pharmaceutical composition according to Claim 1 which is a double-layered tablet consisting of a layer containing the pharmaceutically active substance and a layer containing no pharmaceutically active substance.
Claim 7
Dependent Claim 26 words
A slow-release pharmaceutical composition according to Claim 1 wherein a portion containing the pharmaceutically active substance is coated with a layer containing no pharmaceutically active substance.
Claim 8
Dependent Claim 17 words
A slow-release pharmaceutical composition according to Claim 1 which is a granule containing the pharmaceutically active substance.
Claim 9
Dependent Claim 17 words
A slow-release pharmaceutical composition according to Claim 1 which is an implant containing the pharmaceutically active substance.
Claim 10
Dependent Claim 20 words
A slow-release pharmaceutical composition according to Claim 1 which is in an encapsulated dosage form containing the pharmaceutically active substance.
Claim 11
Dependent Claim 17 words
A slow-release pharmaceutical composition according to Claim 1 which is a troche containing the pharmaceutically active substance.
Claim 12
Dependent Claim 13 words
Use of adenine, cystine and/or tyrosine as slow-re­lease rendering additives in pharmaceutical compositions.
Claim 13
Dependent Claim 13 words
Use of adenine, cystine and/or tyrosine as slow-re­lease rendering additives in pharmaceutical compositions.

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