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EP0282951A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Controlled release preparations of active materials

Assignee: NOF Corp
•
Filing: 1988-03-14
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Granted: —
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Expires: 2008-03-14
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Abstract

Abstract A controlled release preparation of an active material comprising a reaction product obtained by reacting (a) a copolymer consisting essentially of maleic anhydride and at least one polyalkylene glycol ether represented by (I): wherein B represents a residue of a compound having from 2 to 8 hydroxyl groups; R¹ represents an alkenyl group having from 2 to 5 carbon atoms; AO represents an oxyalkylene group having from 2 to 18 carbon atoms or a combination thereof which may be linked together in blocks or at random; R² represents a hydrocarbon group having from 1 to 24 carbon atoms; a represents a positive integer, b and c each represents 0 or a positive integer, and a + b + c = 2 to 8; ℓ ≧ 0, m ≧ 0, n ≧ 0, and ℓ + m + n = 1 to 1000; and (b) an active material. The preparation is soluble both in water and in an organic solvent and exhibits activity for a prolonged period of time.

Inventors

  • 👤 Shin-Ichi Akimoto
  • 👤 Susumu Honda
  • 👤 Tohru Yasukohchi

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-08 13:13
CPC Classifications
C; C08; C08F; C08F222/00; C08F222/04; C08F222/06; A; A61; A61K; A61K47/00; A61K47/50; A61K47/51; A61K47/56; A61K47/58; C08F8/00; C08F8/14; C08F8/30; C08F8/32; C08F8/42; C08F2800/00; C08F2800/10; C08F2800/20; C08F2810/00; C08F2810/30

Claims Analysis

Total Claims: 15
Claim 1
Independent Claim 148 words
A controlled release preparation of an active material comprising a reaction product obtained by reacting (a) a copolymer consisting essentially of maleic anhydride and at least one polyalkylene glycol ether re­presented by formula (I): wherein B represents a residue of a compound having from 2 to 8 hydroxyl groups; R¹ represents an alkenyl group having from 2 to 5 carbon atoms; AO represents an oxy­alkylene group having from 2 to 18 carbon atoms or a combination thereof which may be linked together in blocks or at random; R² represents a hydrocarbon group having from 1 to 24 carbon atoms; a represents a positive integer, b and c each represents 0 or a positive integer, and a + b + c = 2 to 8; ℓ ≧ 0, m ≧ 0, n ≧ 0, and ℓ + m + n = 1 to 1000; and (b) an active material.
Claim 2
Dependent Claim 148 words
A controlled release preparation of an active material comprising a reaction product obtained by reacting (a) a copolymer consisting essentially of maleic anhydride and at least one polyalkylene glycol ether re­presented by formula (I): wherein B represents a residue of a compound having from 2 to 8 hydroxyl groups; R¹ represents an alkenyl group having from 2 to 5 carbon atoms; AO represents an oxy­alkylene group having from 2 to 18 carbon atoms or a combination thereof which may be linked together in blocks or at random; R² represents a hydrocarbon group having from 1 to 24 carbon atoms; a represents a positive integer, b and c each represents 0 or a positive integer, and a + b + c = 2 to 8; ℓ ≧ 0, m ≧ 0, n ≧ 0, and ℓ + m + n = 1 to 1000; and (b) an active material.
Claim 3
Dependent Claim 41 words
A controlled release preparation of an active material as claimed in claim 1, wherein said copolymer further comprises at least one member selected from the group consisting of styrene, methylstyrene, vinyl chloride, vinylidene chloride, isobutylene, diisobutylene, vinyl acetate, acrylonitrile, and acrylamide.
Claim 4
Dependent Claim 28 words
A controlled release preparation of an active material as claimed in claim 1, wherein said active material is a compound having a hydroxyl group or an amino group.
Claim 5
Dependent Claim 36 words
A controlled release preparation of an active material as claimed in claim 3, wherein said compound having a hydroxyl group is a perfume, a growth regulating substance, a pheromone, a hormone, a vitamine or a glycoside.
Claim 6
Dependent Claim 28 words
A controlled release preparation of an active material as claimed in claim 4, wherein said perfume is linalool, geraniol, citronellol, eugenol, benzyl alcohol, phenethyl alcohol or cinnamic alcohol.
Claim 7
Dependent Claim 25 words
A controlled release preparation of an active material as claimed in claim 4, wherein said growth regulating substance is n-decanol, p-menthane-3,8-diol, gibberelline, cytokinin or indol-3-ethanol.
Claim 8
Dependent Claim 21 words
A controlled release preparation of an active material as claimed in claim 4, wherein said pheromone is 9-tetradecene-1-ol, 6-nonene-1-ol or 6-methyl-5-heptene-1-­ol.
Claim 9
Dependent Claim 23 words
8 A controlled release preparation of an active material as claimed in claim 4, wherein said hormone is oestradiol, testosterone, hydroxytestosterone or corti­sone.
Claim 10
Dependent Claim 23 words
9 A controlled release preparation of an active material as claimed in claim 4, wherein said vitamine is vitamine A, B₆ or C.
Claim 11
Dependent Claim 20 words
A controlled release preparation of an active material as claimed in claim 4, wherein said glycoside is saponine or anthocyan.
Claim 12
Dependent Claim 33 words
A controlled release preparation of an active material as claimed in claim 3, wherein said compound having an amino group is an enzyme, a peptide other than enzymes, an aminoglucoside, or a pesticide.
Claim 13
Dependent Claim 28 words
A controlled release preparation of an active material as claimed in claim 11, wherein said enzyme is a hydrolase, an oxidoreductase, an isomerase, a transferase or an eliminase.
Claim 14
Dependent Claim 51 words
A controlled release preparation of an active material as claimed in claim 11, wherein said enzyme is amylase, protease, cellulase, hemicellulase, lipase, pec­tinase, lysozyme, hesperidinase, anthocyanase, amino­acylase, urease, invertase, melibiase, dextranase, pepti­dase, ribonuclease, lactase, glucose oxidase, uricase, catalase, lipoxygenase, cytochrome C, peroxidase, glucose isomerase, cyclodextrin glucosyltransferase, transaminase, aspartase, hyaluronidase, or chondroitinase.
Claim 15
Dependent Claim 20 words
A controlled release preparation of an active material as claimed in claim 11, wherein said pesticide is 3,5-dichloroaniline or 2,6-dichloro-4-nitroaniline.

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