EP0279281A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Lipoxygenase inhibiting compounds
Assignee: Abbott Laboratories
•
Filing: 1988-02-03
•
Granted: —
•
Expires: 2008-02-03
Abstract
Abstract Compounds of the formula: where R₁ is amino or methyl; R₂ is C₁-C₂ alkyl; R₃ is one or more substituents selected from hydrogen, halogen or trihalomethyl; R₄ is one or more substituents selected from hydrogen, halogen, trihalomethyl, C₁ to C₄ alkoxy or C₁ to C₄ alkyl; and M is hydrogen, a pharmaceutically acceptable cation, aroyl, or C₁ to C₆ alkoyl are inhibitors of 5- and/or 12-lipoxygenase enzymes.
Inventors
- 👤 James B. Summers, Jr.
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-04 16:28
CPC Classifications
C; C07; C07C; C07C275/00; C07C275/04; C07C275/20; C07C275/24; C07C275/64; A; A61; A61P; A61P11/00; A61P17/00; A61P27/00; A61P27/16; A61P29/00; A61P37/00; A61P37/08; A61P43/00
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
51 words
Compounds of the formula: R₂ is C₁-C₂ alkyl; R₃, one or more substituents selected from hydrogen, halogen, trihalomethyl; R₄ one or more substituents selected from hydrogen, halogen, trihalomethyl, C₁ to C₄ alkoxy, and C₁ to C₄ alkyl; and M is hydrogen, a pharmaceutically acceptable cation, aroyl, or C₁ to C₆ alkoyl.
Claim 2
Dependent Claim
51 words
Compounds of the formula: R₂ is C₁-C₂ alkyl; R₃, one or more substituents selected from hydrogen, halogen, trihalomethyl; R₄ one or more substituents selected from hydrogen, halogen, trihalomethyl, C₁ to C₄ alkoxy, and C₁ to C₄ alkyl; and M is hydrogen, a pharmaceutically acceptable cation, aroyl, or C₁ to C₆ alkoyl.
Claim 3
Dependent Claim
10 words
A compound according to claim 1, wherein R₂ is methyl.
Claim 4
Dependent Claim
12 words
The compound according to claim 1, wherein R₃ and R₄ are hydrogen.
Claim 5
Dependent Claim
10 words
The compound according to claim 2, wherein R₁ is -NH₂.
Claim 6
Dependent Claim
10 words
The compound according to claim 3, wherein R₁ is -NH₂.
Claim 7
Dependent Claim
79 words
Use of a compound of the formula: wherein R₁ is amino or methyl; R₂ is C₁-C₂ alkyl; R₃, one or more substituents selected from hydrogen, halogen, trihalomethyl; R₄, one or more substituents selected from hydrogen, halogen, trihalomethyl, C₁ to C₄ alkoxy, and C₁ to C₄ alkyl; and M is hydrogen, a pharmaceutically acceptable cation, aroyl, or C₁ to C₆ alkoyl, in preparing a drug useful for inhibiting 5- and/or 12-lipoxygenase activity in a mammal in need of such treatment.
Claim 8
Dependent Claim
79 words
Use of a compound of the formula: wherein R₁ is amino or methyl; R₂ is C₁-C₂ alkyl; R₃, one or more substituents selected from hydrogen, halogen, trihalomethyl; R₄, one or more substituents selected from hydrogen, halogen, trihalomethyl, C₁ to C₄ alkoxy, and C₁ to C₄ alkyl; and M is hydrogen, a pharmaceutically acceptable cation, aroyl, or C₁ to C₆ alkoyl, in preparing a drug useful for inhibiting 5- and/or 12-lipoxygenase activity in a mammal in need of such treatment.
Claim 9
Dependent Claim
9 words
Use according to claim 6, wherein R₂ is methyl.
Claim 10
Dependent Claim
11 words
Use according to claim 6, wherein R₃ and R₄ are hydrogen.
Claim 11
Dependent Claim
10 words
Use according to claim 7 , wherein R₁ is -NH₂.
Claim 12
Dependent Claim
10 words
Use according to claim 8 , wherein R₁ is -NH₂.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
Maintenance schedule is calculated for granted US utility patents.