EP0276977A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Intravascular blood parameter measurement system
Assignee: 3M Co
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Filing: 1988-01-26
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Granted: —
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Expires: 2008-01-26
Abstract
Abstract A parameter of blood is sensed in vivo with a system which includes a catheter (53) and a probe (55). The catheter has a lumen (61) extending therethrough, a proximal end (57), a distal end (59) an opening (63) at the distal end. The probe includes one or more sensors (69) (71) (73) at its distal end. A saline solution is introduced into the lumen (61) so that there is an interface (113) adjacent the distal opening of the catheter between the blood and saline solution. The probe is received within the catheter and affixed thereto. The interface (113) is moved back and forth in the lumen to expose the sensor to blood so that they can sense the blood parameters of interest.
Inventors
- 👤 Thomas P. Maxwell
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-24 07:59
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/68; A61B5/6846; A61B5/6847; A61B5/6852; A61B5/02; A61B5/021; A61B5/0215; A61B5/02158; A61B5/145; A61B5/1455; A61B5/1459
Claims Analysis
Total Claims: 26
Claim 1
Independent Claim
111 words
An assembly for in vivo measurement of the concentration of oxygen in blood comprising: a fluorescent oxygen sensor for sensing the concentration of oxygen in blood and providing a fluorescent oxygen signal in response thereto; elongated optical transmission means for transmitting the fluorescent oxygen signal from the sensor proximally; said sensor being carried by a distal portion of the transmission means; said sensor and said transmission means being sized and adapted to be received within a vessel of a patient; and means for keeping the sensor from contacting the wall of this vessel when the sensor is within such vessel to thereby reduce the wall effect on the fluorescent oxygen signal.
Claim 2
Dependent Claim
111 words
An assembly for in vivo measurement of the concentration of oxygen in blood comprising: a fluorescent oxygen sensor for sensing the concentration of oxygen in blood and providing a fluorescent oxygen signal in response thereto; elongated optical transmission means for transmitting the fluorescent oxygen signal from the sensor proximally; said sensor being carried by a distal portion of the transmission means; said sensor and said transmission means being sized and adapted to be received within a vessel of a patient; and means for keeping the sensor from contacting the wall of this vessel when the sensor is within such vessel to thereby reduce the wall effect on the fluorescent oxygen signal.
Claim 3
Dependent Claim
79 words
An assembly as defined in claims 1 wherein said keeping means includes a catheter having a lumen extending therethrough, a proximal end, a distal end and a distal opening at the distal end, at least a portion of said transmission means is in said lumen with a radial clearance and means for attaching the transmission means to the catheter adjacent the proximal end of the catheter such that the oxygen sensor is within the lumen adjacent the distal opening.
Claim 4
Dependent Claim
143 words
A probe-catheter assembly comprising: a probe including a first sensor for sensing a parameter of blood and providing a signal in response thereto and elongated transmission means for transmitting the signal from the sensor proximally, said sensor being carried by a distal portion of the transmission means; a catheter having a lumen extending therethrough, a proximal end, a distal end and a distal opening at the distal end, a major length of said probe being receivable longitudinally in said lumen of said catheter with radial clearance to allow fluid flow therein and a length of the catheter being sized to be received within the cardiovascular system of a patient; and means for attaching the probe to the catheter at a location adapted to be outside the cardiovascular system of the patient such that the sensor is within the lumen adjacent the distal opening.
Claim 5
Dependent Claim
143 words
A probe-catheter assembly comprising: a probe including a first sensor for sensing a parameter of blood and providing a signal in response thereto and elongated transmission means for transmitting the signal from the sensor proximally, said sensor being carried by a distal portion of the transmission means; a catheter having a lumen extending therethrough, a proximal end, a distal end and a distal opening at the distal end, a major length of said probe being receivable longitudinally in said lumen of said catheter with radial clearance to allow fluid flow therein and a length of the catheter being sized to be received within the cardiovascular system of a patient; and means for attaching the probe to the catheter at a location adapted to be outside the cardiovascular system of the patient such that the sensor is within the lumen adjacent the distal opening.
Claim 6
Dependent Claim
31 words
A probe-catheter assembly as defined in claims 1, 2 or 3 wherein the distal opening opens axially and said sensor has a distal end within about .125 inch of said opening.
Claim 7
Dependent Claim
57 words
A probe-catheter assembly as defined in claims 2,3 or 4 including a second sensor for sensing a parameter of blood and providing a signal in response thereto, and said first and second sensors are within said lumen at different axial positions along the distal portion of the transmission means when the probe is received within the lumen.
Claim 8
Dependent Claim
32 words
A probe-catheter assembly as defined in claims 2, 3, 4 or 5 including at least one radial aperture in the catheter leading from said lumen adjacent the distal end of the catheter.
Claim 9
Dependent Claim
70 words
A probe-catheter assembly as defined in claims 5 or 6 wherein said transmission means includes first and second elongated optical fibers, each of said first and second optical fibers has a distal end, said first and second sensors are optical sensors carried by the first and second optical fibers, respectively, adjacent the distal ends thereof and said sensors are within the lumen when the probe is received within the lumen.
Claim 10
Dependent Claim
62 words
A probe-catheter assembly as defined in claims 2, 3, 4, 5, 6 or 7 wherein said probe terminates distally in said sensor and said sensor confronts said opening,said means for attaching allows attachment of the probe to the catheter when the catheter is received within the cardiovascular system of the patient, said means for attaching releasably attaches the probe to the catheter.
Claim 11
Dependent Claim
99 words
A probe for sensing at least one parameter in blood comprising: first and second sensors for sensing at least one parameter in blood and providing a signal response thereto; elongated transmission means for transmitting the signals from the first and second sensors proximally; said first and second sensors being carried by a distal portion of the transmission means with the first and second sensors being at different longitudinal positions along the distal portion of the transmission means; and said transmission means and said first and second sensors being sized to be received in the cardiovascular system of a patient.
Claim 12
Dependent Claim
99 words
A probe for sensing at least one parameter in blood comprising: first and second sensors for sensing at least one parameter in blood and providing a signal response thereto; elongated transmission means for transmitting the signals from the first and second sensors proximally; said first and second sensors being carried by a distal portion of the transmission means with the first and second sensors being at different longitudinal positions along the distal portion of the transmission means; and said transmission means and said first and second sensors being sized to be received in the cardiovascular system of a patient.
Claim 13
Dependent Claim
26 words
A probe as defined in claims 3 and 9 wherein said transmission means includes means for transmitting light and said first sensor is an optical sensor.
Claim 14
Dependent Claim
67 words
A probe as defined in claims 5, 9 and 10 wherein said transmission means includes first and second elongated optical fibers, each of said first and second optical fibers has a distal end, said first and second sensors are optical sensors carried by the first and second optical fibers, respectively, adjacent the distal ends thereof, and said first optical fiber extends distally beyond the second optical fiber.
Claim 15
Dependent Claim
40 words
A probe as defined in claims 5, 7, 9, 10 or 11 wherein said first and second sensors sense first and second different parameters in blood, respectively, and said first and second parameters are a blood gas and pH, respectively.
Claim 16
Dependent Claim
34 words
A probe as defined in claims 5, 7, 9, 10 or 11 wherein said first and second sensors sense oxygen and carbon dioxide and the first sensor is located proximally of the second sensor.
Claim 17
Independent Claim
129 words
A method of sensing a parameter of blood in vivo comprising: providing a catheter and a sensor in a vessel of a patient with the catheter having a lumen extending therethrough, a proximal end, and a distal end and an opening and with the sensor being within the lumen and capable of sensing a parameter in blood and providing a signal in response thereto; introducing an anti-clotting solution into the lumen from a solution-introducing system so that there is an interface between the blood and the solution; moving the interface back and forth in the lumen so that the sensor is exposed to blood for at least a portion of the time that the interface is moving; and obtaining said signal from the sensor during said step of moving.
Claim 18
Independent Claim
129 words
A method of sensing a parameter of blood in vivo comprising: providing a catheter and a sensor in a vessel of a patient with the catheter having a lumen extending therethrough, a proximal end, and a distal end and an opening and with the sensor being within the lumen and capable of sensing a parameter in blood and providing a signal in response thereto; introducing an anti-clotting solution into the lumen from a solution-introducing system so that there is an interface between the blood and the solution; moving the interface back and forth in the lumen so that the sensor is exposed to blood for at least a portion of the time that the interface is moving; and obtaining said signal from the sensor during said step of moving.
Claim 19
Independent Claim
132 words
A method of sensing a parameter of blood in vivo comprising: providing a catheter and a sensor in a vessel of a patient with the catheter having a lumen extending therethrough, a proximal end, and a distal end and an opening and with the sensor being within the lumen and capable of sensing a parameter in blood and providing a signal in response thereto; introducing an anti-clotting solution into the lumen from a variable volume solution-introducing system so that there is a net flow of solution through the distal opening into the vessel of the patient; and moving blood from the vessel through the distal opening into the lumen during said step of introducing to expose the sensor to blood and obtain a signal in response to said parameter of the blood.
Claim 20
Independent Claim
132 words
A method of sensing a parameter of blood in vivo comprising: providing a catheter and a sensor in a vessel of a patient with the catheter having a lumen extending therethrough, a proximal end, and a distal end and an opening and with the sensor being within the lumen and capable of sensing a parameter in blood and providing a signal in response thereto; introducing an anti-clotting solution into the lumen from a variable volume solution-introducing system so that there is a net flow of solution through the distal opening into the vessel of the patient; and moving blood from the vessel through the distal opening into the lumen during said step of introducing to expose the sensor to blood and obtain a signal in response to said parameter of the blood.
Claim 21
Independent Claim
32 words
A method as defined in claims 14 or 15 wherein said step of moving includes providing the introducing system with a volume oscillator and allowing the volume oscillator to move the interface.
Claim 22
Independent Claim
32 words
A method as defined in claims 14 or 15 wherein said step of moving includes providing the introducing system with some compliance and allowing the patient's heart beats to move the interface.
Claim 23
Independent Claim
40 words
A method as defined in claims 14, 15, 16 or 17 wherein said step of introducing includes introducing the anti-clotting solution to the lumen to produce a net flow of solution through the opening into the vessel of the patient.
Claim 24
Independent Claim
50 words
A method as defined in claims 14, 15, 16, 17 or 18 wherein said step of moving includes providing the introducing systems with a compliant element, switching the compliant element out of the introducing system and taking a blood pressure reading with the compliant element out of the introducing system.
Claim 25
Dependent Claim
129 words
An assembly for the in vivo measurement of a blood parameter comprising: a catheter having a lumen extending therethrough, a proximal end, a distal end and a distal opening at the distal end; a sensor for sensing the blood parameter and providing a signal in response thereto; means for mounting the sensor on the catheter with the sensor being within the lumen adjacent the distal opening; a conduit for coupling the lumen to a source of fluid whereby the fluid can be supplied to the lumen; a compliant element coupled to said conduit to allow the volume of the introducing system to be expanded and contracted; and means for selectively nullifying the ability of the compliant element to allow expansion and contraction of the volume of the introducing system.
Claim 26
Dependent Claim
129 words
An assembly for the in vivo measurement of a blood parameter comprising: a catheter having a lumen extending therethrough, a proximal end, a distal end and a distal opening at the distal end; a sensor for sensing the blood parameter and providing a signal in response thereto; means for mounting the sensor on the catheter with the sensor being within the lumen adjacent the distal opening; a conduit for coupling the lumen to a source of fluid whereby the fluid can be supplied to the lumen; a compliant element coupled to said conduit to allow the volume of the introducing system to be expanded and contracted; and means for selectively nullifying the ability of the compliant element to allow expansion and contraction of the volume of the introducing system.
References Cited (Backward Citations)
No citation records indexed.
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