EP0273452A2
Expired / Lapsed
EP
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High molecular compound comprising unit of asialoglycoprotein acceptor-directing compound and unit of chelate-forming compound chemically bonded thereto, and its utilisation
Assignee: Nihon Medi Physics Co Ltd
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Filing: 1987-12-30
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Granted: —
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Expires: 2007-12-30
Abstract
Abstract A high molecular compound useful as a non-radioactive carrier, which comprises at least one unit of (1) an asialoglycoprotein acceptor-directing compound and at least one unit of (2) a chelate-forming compound chemically bonded thereto, and which may be labeled with a radioactive metallic element to give a radioactive metallic element-labeled product useful as a radioactive diagnostic or therapeutic agent for liver.
Inventors
- 👤 Komei Washino
- 👤 Miki Kurami
- 👤 Nobuo Ueda
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-07 22:11
CPC Classifications
A; A61; A61K; A61K51/00; A61K51/02; A61K51/04; A61K51/08; A61K51/088; A61K51/0491; A61K51/081; A61K2121/00; A61K2123/00
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
39 words
A high molecular compound useful as a non-radioactive carrier for a raiodactive metallic element, which comprises at least one unit of (1) an asialoglycoprotein acceptor-directing compound and at least one unit of (2) a chelate-forming compound chemically bonded thereto.
Claim 2
Dependent Claim
39 words
A high molecular compound useful as a non-radioactive carrier for a raiodactive metallic element, which comprises at least one unit of (1) an asialoglycoprotein acceptor-directing compound and at least one unit of (2) a chelate-forming compound chemically bonded thereto.
Claim 3
Dependent Claim
30 words
The high molecular compound according to claim 1, wherein the chelate-forming compound (2) consists of a lower molecular weight compound having at least one chelate-forming structure and a functional group.
Claim 4
Dependent Claim
48 words
The high molecular compound according to claim 1, wherein the chelate-forming compound (2) consists of a unit of a higher molecular weight compound having at least two functional groups and a unit of a lower molecular weight compound having at least one chelate-forming structure and a functional group.
Claim 5
Dependent Claim
50 words
The high molecular compound according to claim 1, wherein the chelate-forming compound (2) consists of one unit of a higher molecular weight compound having at least three functional groups and at least two units of a lower molecular weight compound having at least one chelate-forming structure and a functional group.
Claim 6
Dependent Claim
49 words
A radioactive metallic element-labeled high molecular compound useful as a nuclear medicine, which comprises at least one unit of (1) an asialoglycoprotein acceptor-directing compound, at least one unit of (2) a chelate-forming compound chemically bonded thereto and (3) at least one radioactive metallic element chelate-bonded to said chelate-forming compound.
Claim 7
Dependent Claim
49 words
A radioactive metallic element-labeled high molecular compound useful as a nuclear medicine, which comprises at least one unit of (1) an asialoglycoprotein acceptor-directing compound, at least one unit of (2) a chelate-forming compound chemically bonded thereto and (3) at least one radioactive metallic element chelate-bonded to said chelate-forming compound.
Claim 8
Dependent Claim
31 words
The labeled high molecular compound according to claim 5, wherein the chelate-forming compound (2) consists of a lower molecular weight compound having at least one chelate-forming structure and a functional group.
Claim 9
Dependent Claim
49 words
The labeled high molecular compound according to claim 5, wherein the chelate-forming compound (2) consists of a unit of a higher molecular weight compound having at least two functional groups and a unit of a lower molecular weight compound having at least one chelate-forming structure and a functional group.
Claim 10
Dependent Claim
50 words
The high molecular compound according to claim 5, wherein the chelate-forming compound (2) consists of one unit of a higher molecular weight compound having at least three functional groups and at least two units of a lower molecular weight compound having at least one chelate-forming structure and a functional group.
Claim 11
Dependent Claim
25 words
A process for preparing the high molecular compound according to claim 1, which comprises reacting the asialoglycoprotein acceptor-directing compound (1) with the chelate-forming compound (2).
Claim 12
Dependent Claim
32 words
A process for preparing the radioactive metallic element-labeled high molecular compound according to claim 5, which comprises reacting the high molecular compound according to claim 1 with the radioactive metallic element (3).
References Cited (Backward Citations)
No citation records indexed.
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