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EP0270690A1 Expired / Lapsed EP ⏱️ 0.0 years remaining

Drug for treatment and prophylaxis of kidney and liver diseases

Assignee: DIC Corp
•
Filing: 1987-06-22
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Granted: —
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Expires: 2007-06-22
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Abstract

Abstract A drug for treatment and prophylaxis of kidney and liver diseases, including complication, which contains as an effective ingredient isoliquiritigenin represented by general formula (I).

Inventors

  • 👤 Toshio Sato
  • 👤 Hitoshi Matsumoto
  • 👤 Hisao Kakegawa

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-02 20:23
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/12

Claims Analysis

Total Claims: 151
Claim 1
Independent Claim 20 words
A medicine for use in the therapy and prevention of kidney diseases characterized in containing isoliquiritigenin as the active ingredient.
Claim 2
Dependent Claim 20 words
A medicine for use in the therapy and prevention of kidney diseases characterized in containing isoliquiritigenin as the active ingredient.
Claim 3
Dependent Claim 26 words
A medicine for use in the therapy and prevention of kidney diseases according to claim 1, wherein 0.1 to 100% by weight of isoliquiritigenin is contained.
Claim 4
Dependent Claim 52 words
A medicine for use in the therapy and prevention of kidney diseases according to claim 2, prepared in a formulation such as a tablet, a capsule, a granule, a powder, a fine granule, a pill, a troche, a buccal, a suppository, an ointment, an injection, an emulsion, a suspension, or a syrup.
Claim 5
Dependent Claim 59 words
A medicine for use in the therapy and prevention of kidney diseases according to claim 3, further containing at least one additive such as an excipient, a binder, a disintegrator, a lubricant, a preservative, an antioxidant, an isotonizing agent, a buffer, a coating agent, a corrigent, a solution adjuvant, a base, a dispersing agent, a stabilizer, or a colorant.
Claim 6
Dependent Claim 48 words
A medicine for use in the therapy and prevention of kidney diseases according to claim 1, wherein said kidney diseases are at least one of acute nephritis caused by functional disorders of kidney caused by abnormality in the metabolic functions, and chronic nephritis developed from such acute nephritis.
Claim 7
Dependent Claim 26 words
A medicine for use in the therapy and prevention of kidney diseases according to claim 5, wherein 0.1 to 100% by weight of isoliquiritigenin is contained.
Claim 8
Dependent Claim 52 words
A medicine for use in the therapy and prevention of kidney diseases according to claim 6, prepared in a formulation such as a tablet, a capsule, a granule, a powder, a fine granule, a pill, a troche, a buccal, a suppository, an ointment, an injection, an emulsion, a suspension, or a syrup.
Claim 9
Dependent Claim 59 words
A medicine for use in the therapy and prevention of kidney diseases according to claim 7, further containing at least one additive such as an excipient, a binder, a disintegrator, a lubricant, a preservative, an antioxidant, an isotonizing agent, a buffer, a coating agent, a corrigent, a solution adjuvant, a base, a dispersing agent, a stabilizer, or a colorant.
Claim 10
Dependent Claim 53 words
A medicine for use in the therapy and prevention of kidney diseases according to claim 1, wherein said kidney diseases are at lease one of a group of functional disorders of the kidney consisting of acute nephritis caused by the intermediary of the immunological mechanism, and chronic nephritis developed from such acute nephritis.
Claim 11
Dependent Claim 26 words
A medicine for use in the therapy and prevention of kidney diseases according to claim 9, wherein 0.1 to 100% by weight of isoliquiritigenin is contained.
Claim 12
Dependent Claim 53 words
ll. A medicine for use in the therapy and prevention of kidney diseases according to claim 10, prepared in a formulation such as a tablet, a capsule, a granule, a powder, a fine granule, a pill, a troche, a buccal, a suppository, an ointment, an injection, an emulsion, a suspension, or a syrup.
Claim 13
Dependent Claim 59 words
A medicine for use in the therapy and prevention of kidney diseases according to claim 11, further containing at least one additive such as an excipient, a binder, a disintegrator, a lubricant, a preservative, an antioxidant, an isotonizing agent, a buffer, a coating agent, a corrigent, a solution adjuvant, a base, a dispersing agent, a stabilizer, or a colorant.
Claim 14
Dependent Claim 51 words
A medicine for use in the therapy and prevention of kidney diseases according to claim 1, wherein said kidney diseases are at least one of a group of functional disorders of the kidney consisting of acute nephritis caused by bacteria and virus infection, and chronic nephritis developed from such acute nephritis.
Claim 15
Dependent Claim 26 words
A medicine for use in the therapy and prevention of kidney diseases according to claim 13, wherein 0.1 to 100% by weight of isoliquiritigenin is contained.
Claim 16
Dependent Claim 52 words
A medicine for use in the therapy and prevention of kidney diseases according to claim 14, prepared in a formulation such as a tablet, a capsule, a granule, a powder, a fine granule, a pill, a troche, a buccal, a suppository, an ointment, an injection, an emulsion, a suspension, or a syrup.
Claim 17
Dependent Claim 59 words
A medicine for use in the therapy and prevention of kidney diseases according to claim 15, further containing at least one additive such as an excipient, a binder, a disintegrator, a lubricant, a preservative, an antioxidant, an isotonizing agent, a buffer, a coating agent, a corrigent, a solution adjuvant, a base, a dispersing agent, a stabilizer, or as colorant.
Claim 18
Dependent Claim 39 words
A medicine for use in the therapy and prevention of kidney diseases according to claim 1, wherein said kidney diseases are functional disorders of at least one kidney portion such as the glomerulus, the renal tubule, or the lupus.
Claim 19
Dependent Claim 26 words
A medicine for use in the therapy and prevention of kidney diseases according to claim 17, wherein 0.1 to 100% by weight of isoliquiritigenin is contained.
Claim 20
Dependent Claim 52 words
A medicine for use in the therapy and prevention of kidney diseases according to claim 18, prepared in a formulation such as a tablet, a capsule, a granule, a powder, a fine granule, a pill, a troche, a buccal, a suppository, an ointment., an injection, an emulsion, a suspension, or a syrup.
Claim 21
Dependent Claim 58 words
A medicine for use'in the therapy and prevention of kidney diseases according to claim 19, further containing at least one additive such as an excipient, a binder, a disintegrator, a lubricant, a preservative, an antioxidant, an isotonizing agent, a buffer, a coating agent, a corrigent, a solution adjuvant, a base, a dispersing agent, a stabilizer, or a colorant.
Claim 22
Dependent Claim 48 words
A medicine for use in the therapy and prevention of kidney diseases according to claim 5, wherein said functional disorders of the kidney caused by abnormality in the metabolic functions are at least one of acute nephritis caused by drugs, and chronic nephritic developed from such acute nephritis.
Claim 23
Dependent Claim 26 words
A medicine fnr use in the therapy and prevention of kidney diseases according to claim 21, wherein 0.1 to 100% by weight of isoliquiritigenin is contained.
Claim 24
Dependent Claim 52 words
A medicine for use in the therapy and prevention of kidney diseases according to claim 22, prepared in a formulation such as a tablet, a capsule, a granule, a powder, a fine granule, a pill, a troche, a buccal, a suppository, an ointment, an injection, an emulsion, a suspension, or a syrup.
Claim 25
Dependent Claim 59 words
A medicine for use in the therapy and prevention of kidney diseases according to claim 23, further containing at least one additive such as an excipient, a binder, a disintegrator, a lubricant, a preservative, an antioxidant, an isotonizing agent, a buffer, a coating agent, a corrigent, a solution adjuvant, a base, a dispersing agent, a stabilizer, or a colorant.
Claim 26
Dependent Claim 20 words
A medicine for use in the therapy and prevention of liver diseases characterized in containing isoliquiritigenin as the active ingredient.
Claim 27
Dependent Claim 20 words
A medicine for use in the therapy and prevention of liver diseases characterized in containing isoliquiritigenin as the active ingredient.
Claim 28
Dependent Claim 26 words
A medicine for use in the therapy and prevention of liver diseases according to claim 25, wherein 0.1 to 100% by weight of isoliquiritigenin is contained.
Claim 29
Dependent Claim 52 words
A medicine for use in the therapy and prevention of liver diseases according to claim 26, prepared in a formulation such as a tablet, a capsule, a granule, a powder, a fine granule, a pill, a troche, a buccal, a suppository, an ointment, an injection, an emulsion, a suspension, or a syrup.
Claim 30
Dependent Claim 59 words
A medicine for use in the therapy and prevention of liver diseases according to claim 27, further containing at least one additive such as an excipient, a binder, a disintegrator, a lubricant, a preservative, an antioxidant, an isotonizing agent, a buffer, a coating agent, a corrigent, a solution adjuvant, a base, a dispersing agent, a stabilizer, or a colorant.
Claim 31
Dependent Claim 38 words
A medicine for use in the therapy and prevention of liver diseases according to claim 25, wherein said liver diseases are functional disorders of the liver caused by abnormality in the metabolic functions and in the biosyntheti.c functions..
Claim 32
Dependent Claim 28 words
- 30. A medicine for use in the therapy and prevention of liver diseases according to claim 29, wherein 0.1 to 100% by weight of isoliquiritigenin is contained.
Claim 33
Dependent Claim 52 words
A medicine for use in the therapy and prevention of liver diseases according to claim 30, prepared in a formulation such as a tablet, a capsule, a granule, a powder, a fine granule, a pill, a troche, a buccal, a suppository, an ointment, an injection, an emulsion, a suspension, or a syrup.
Claim 34
Dependent Claim 59 words
A medicine for use in the therapy and prevention of liver diseases according to claim 31, further containing at least one additive such as an excipient, a binder, a disintegrator, a lubricant, a preservative, an antioxidant, an isotonizing agent, a buffer, a coating agent, a corrigent, a solution adjuvant, a base, a dispersing agent, a stabilizer, or a colorant.
Claim 35
Dependent Claim 30 words
A medicine for use in the therapy and prevention of kidney diseases according to claim 25, wherein said liver diseases are fatty liver or chronic hepatitis developed from fatty liver.
Claim 36
Dependent Claim 26 words
A medicine for use in the therapy and prevention of kidney diseases according to claim 33, wherein 0.1 to 100% by weight of isoliquiritigenin is contained.
Claim 37
Dependent Claim 52 words
A medicine for use in the therapy and prevention of liver diseases according to claim 34, prepared in a formulation such as a tablet, a capsule, a granule, a powder, a fine granule, a pill, a troche, a buccal, a suppository, an ointment, an injection, an emulsion, a suspension, or a syrup.
Claim 38
Dependent Claim 59 words
A medicine for use in the therapy and prevention of liver diseases according to claim 35, further containing at least one additive such as an excipient, a binder, a disintegrator, a lubricant, a preservative, an antioxidant, an isotonizing agent, a buffer, a coating agent, a corrigent, a solution adjuvant, a base, a dispersing agent, a stabilizer, or a colorant.
Claim 39
Dependent Claim 34 words
A medicine for use in the therapy and prevention of liver diseases according to claim 25, wherein said liver diseases are viral hepatitis caused by virus infection or chronic hepatitis developed from such hepatitis.
Claim 40
Dependent Claim 26 words
A medicine for use in the therapy and prevention of liver diseases according to claim 37, wherein 0.1 to 100% by weight of isoliquiritigenin is contained.
Claim 41
Dependent Claim 52 words
A medicine for use in the therapy and prevention of liver diseases according to claim 38, prepared in a formulation such as a tablet, a capsule, a granule, a powder, a fine granule, a pill, a troche, a buccal, a suppository, an ointment, an injection, an emulsion, a suspension, or a syrup.
Claim 42
Dependent Claim 60 words
A medicine for use in the therapy and prevention of liver diseases according to claim 39, further containing at least one additive such as an excipient, a binder, a disintegrator, a lubricant, a preservative, an antioxidant, an isotonizing agent, a buffer, a coatin q agent, a corrigent, a solution adjuvant, a base, a dispersing agent, a stabilizer, or a colorant.
Claim 43
Dependent Claim 28 words
A medicine for use in the therapy and prevention of complications resulting from diseases of the kidney and the liver characterized in containing isoliquiritigenin as the active ingredient.
Claim 44
Dependent Claim 28 words
A medicine for use in the therapy and prevention of complications resulting from diseases of the kidney and the liver characterized in containing isoliquiritigenin as the active ingredient.
Claim 45
Dependent Claim 32 words
A medicine for use in the therapy and prevention of complicated diseases of the kidney and the liver according to claim 41, wherein 0.1 to 100% by weight of isoliquiritigenin is contained.
Claim 46
Dependent Claim 58 words
A medicine for use in the therapy and prevention of complicated diseases of the kidney and the liver according to claim 42, prepared in a formulation such as a tablet, a capsule, a granule, a powder, a fine granule, a pill, a troche, a buccal, a suppository, an ointment, an injection, an emulsion, a suspension, or a syrup.
Claim 47
Dependent Claim 65 words
A medicine for use in the therapy and prevention of complicated diseases of the kidney and the liver according to claim 43, further containing at least one additive such as an excipient, a binder, a disintegrator, a lubricant, a preservative, an antioxidant, an isotonizing agent, a buffer, a coating agent, a corrigent, a solution adjuvant, a base, a dispersing agent, a stabilizer, or a colorant.
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Dependent Claim 29 words
(Added) Use of isoliquiritigenin in the preparation of a medicine for the therapy and prevention of kidney diseases, liver diseases, or complicated diseases of the kidney and the liver.
Claim 137
Dependent Claim 29 words
(Added) Use of isoliquiritigenin in the preparation of a medicine for the therapy and prevention of kidney diseases, liver diseases, or complicated diseases of the kidney and the liver.
Claim 138
Dependent Claim 14 words
(Added) Use of isoliquiritigenin according to Claim 45, wherein said diseases are kidney diseases.
Claim 139
Dependent Claim 40 words
(Added) Use of isoliquiritigenin according to Claim 46, wherein said kidney diseases are at least one of acute nephritis caused by functional disorders of kidney caused by abnormality in the metabolic functions, and chronic nephritis developed from such acute nephritis.
Claim 140
Dependent Claim 19 words
(Added) Use of isoliquiritigenin according to Claim 47, wherein said abnormality in the metabolic functions is caused by drugs.
Claim 141
Dependent Claim 45 words
(Added) Use of isoliquiritigenin according to Claim 46, wherein said kadney diseases are at least one of a group of functional disorders of the kidney consisting of acute nephritis caused by the intermediary of the immunological mechanism, and chronic nephritis developed from such acute nephritis.
Claim 142
Dependent Claim 43 words
(Added) Use of isoiquiritigenin according to Claim 46, wherein said kidney diseases are at least one of a group of functional disorders of the kidney consisting of acute nephritis caused by bacteria and virus infection, and chronic nephritis developed form such acute nephritis.
Claim 143
Dependent Claim 31 words
(Added) Use of isoliquiritigenin according to Claim 46, wherein said kidney diseases are functional disorders of at least one kidney portion such as the glomerulus, the renal tubule, or the lupus.
Claim 144
Dependent Claim 14 words
(Added) use of isoliquirittgenin according to Claim 45, wherein said diseases are liver diseases.
Claim 145
Dependent Claim 30 words
(Added) Use of isoliquiritigenin according to Claim 52, wherein said liver diseases are functional disorders of the liver caused by abnormality in the metabolic functions and in the biosynthetic functions.
Claim 146
Dependent Claim 24 words
(Added) Use of isoliquiritigenin according to Claim 53, wherein said abnormality in the metabolic functions and in the biosynthetic functions is caused by drugs.
Claim 147
Dependent Claim 22 words
(Added) Use of isoliquiritigenin according to Claim 52, wherein said liver diseases are fatty liver or chronic hepatitis developed from fatty liver.
Claim 148
Dependent Claim 26 words
(Added) Use of isoliquiritigenin according to Claim 52, wherein said liver diseases are viral hepatitis caused by virus infection or chronic hepatitis developed from such hepatitis.
Claim 149
Dependent Claim 20 words
(Added) Use of isoliquiritigenin according to Claim 45, wherein said diseases are complicated diseases of the kidney and the liver.
Claim 150
Dependent Claim 42 words
(Added) A method for the therapy and prevention of kidne diseases, liver diseases, or complicated diseases of the kidney and the liver, comprising administering a mammal with a medicine containing a therapeutically or prophylactically effective amount of isoliquiritigenin as an active ingredient.
Claim 151
Dependent Claim 42 words
(Added) A method for the therapy and prevention of kidne diseases, liver diseases, or complicated diseases of the kidney and the liver, comprising administering a mammal with a medicine containing a therapeutically or prophylactically effective amount of isoliquiritigenin as an active ingredient.

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