EP0268463A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Zinc based ceramics
Assignee: University of Dayton
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Filing: 1987-11-18
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Granted: —
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Expires: 2007-11-18
Abstract
Abstract A bioceramic is provided comprising about 10 to 50 wt. % zinc oxide or zinc sulfate or mixtures thereof, about 30 to 40 wt. % calcium oxide and about 10 to 40 wt. % phosphorus pentoxide. A surgical cement composition is also provided comprising the bioceramic and a setting agent, said bioceramic comprising zinc oxide, calcium oxide and phosphorus pentoxide. The bioceramic is also useful as a drug delivery device.
Inventors
- 👤 Praphulla K. Bajpai
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 02:44
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/02; A61L27/12; A61L24/00; A61L24/0047; A61L24/0073; A61L24/0084; C; C04; C04B; C04B35/00; C04B35/01; C04B35/447; C04B35/453; A61F; A61F2310/00; A61F2310/00005; A61F2310/00179; A61F2310/00293
Claims Analysis
Total Claims: 22
Claim 1
Independent Claim
34 words
A bioceramic comprising about 10 to 50% by weight zinc oxide or zinc sulfate or mixtures thereof, about 30 to 40% by weight calcium oxide and about 10 to 40% by weight phosphorus pentoxide.
Claim 2
Dependent Claim
34 words
A bioceramic comprising about 10 to 50% by weight zinc oxide or zinc sulfate or mixtures thereof, about 30 to 40% by weight calcium oxide and about 10 to 40% by weight phosphorus pentoxide.
Claim 3
Dependent Claim
22 words
A bioceramic according to claim 1, characterized in that said bioceramic comprises said zinc oxide, said calcium oxide and said phosphorus pentoxide.
Claim 4
Dependent Claim
21 words
A bioceramic according to claim 2, characterized in that said ceramic has a particle size of about 1 to 400 microns.
Claim 5
Dependent Claim
39 words
A porous resorbable ceramic according to claim 3, characterized in that said ceramic comprises about 30 to 50% by weight zinc oxide, about 30 to 40% by weight calcium oxide and about 20 to 40% by weight phosphorus pentoxide.
Claim 6
Dependent Claim
46 words
A surgical cement composition comprising a powdered bioceramic and a setting agent, said bioceramic comprising about 10 to 50 wt % zinc oxide or zinc sulfate or mixtures thereof, about 30 to 40 wt % calcium oxide and about 10 to 40 wt. % phosphorus pentoxide.
Claim 7
Dependent Claim
46 words
A surgical cement composition comprising a powdered bioceramic and a setting agent, said bioceramic comprising about 10 to 50 wt % zinc oxide or zinc sulfate or mixtures thereof, about 30 to 40 wt % calcium oxide and about 10 to 40 wt. % phosphorus pentoxide.
Claim 8
Dependent Claim
24 words
A surgical cement composition according to claim 5, characterized in that said bioceramic comprises said zinc oxide, said calcium oxide and said phosphorus pentoxide.
Claim 9
Dependent Claim
35 words
A surgical cement composition according to claim 6, characterized in that said setting agent is selected from the group consisting of amines, amino acids, polyfunctional carboxylic acids, polymers reactive with said bioceramic and mixtures thereof.
Claim 10
Dependent Claim
28 words
A surgical cement composition according to claim 7, characterized in that said amine is selected from the group consisting of carbodiimides; N,N-dimethyl-p-toluidine; N,N-diethyl-p-toluidine; N,N-dimethylaniline; N,N-diethylaniline and mixtures thereof.
Claim 11
Dependent Claim
40 words
A surgical cement composition according to claim 7, characterized in that said amino acid is selected from the group consisting of alanine, arginine, asparagine, cysteine, glutamine, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, proline, serine, threonine, valine and mixtures thereof.
Claim 12
Dependent Claim
38 words
A surgical cement composition according to claim 7, characterized in that said polyfunctional carboxylic acid is selected from the group consisting of aconitic, alpha-ketoglutaric, citraconic, citric, fumaric, glutaconic, itaconic, maleic, malic, pyruvic, oxalic, succinic, tartaric and mixtures thereof.
Claim 13
Dependent Claim
23 words
A surgical cement composition according to claim 7, characterized in that said bioceramic has a particle size of about 1 to 400 microns.
Claim 14
Dependent Claim
18 words
A surgical cement composition according to claim 11, characterized in that said cement further comprises a calcium salt.
Claim 15
Dependent Claim
27 words
A surgical cement composition according to claim 7, characterized in that said polymer is selected from the group consisting of polylactic acid, polyacrylic acid, and polymethacrylic acid.
Claim 16
Dependent Claim
34 words
A surgical cement composition according to claim 5, characterized in that the ratio of said resorbable ceramic to said setting agent based on the weight of said cement composition is about 1:1 to 3:1.
Claim 17
Dependent Claim
41 words
An implant comprising about 10 to 50% by weight zinc oxide or zinc sulfate or mixtures thereof, about 30 to 40% by weight calcium oxide and about 10 to 40% by weight phosphorus pentoxide, said implant being essentially non-toxic and bioabsorbable.
Claim 18
Dependent Claim
41 words
An implant comprising about 10 to 50% by weight zinc oxide or zinc sulfate or mixtures thereof, about 30 to 40% by weight calcium oxide and about 10 to 40% by weight phosphorus pentoxide, said implant being essentially non-toxic and bioabsorbable.
Claim 19
Dependent Claim
22 words
An implant according to claim 15, characterized in that said implant comprises said zinc oxide, said calcium oxide and said phosphorus pentoxide.
Claim 20
Dependent Claim
84 words
An implant according to claim 16, characterized in that said implant is formed by the process comprising the steps of: mixing said oxides and compressing said mixture, calcining said mixture at about 700 to 1300°C for about 24 to 36 hours, powdering said calcined mixture and sieving said mixture to obtain particles of a size from about 1 to 50 microns, mixing said mixture with a binder and compressing at a pressure of about 2000 to 20,000 pounds total load and sintering said mixture.
Claim 21
Dependent Claim
23 words
An implant according to claim 17, characterized in that after sintering, said implant has a pore size of about 1 to 400 microns.
Claim 22
Dependent Claim
37 words
An implant according to claim 18, characterized in that said implant comprises about 30 to 50% by weight zinc oxide, about 30 to 40% by weight calcium oxide and about 20 to 40% by weight phosphorus pentoxide.
References Cited (Backward Citations)
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